Birla Institute of Technology, Mesra
Dr. Shashwati Ghosh Sachan
Associate Professor, Bioengineering and Biotechnology
M.Sc., Ph.D. 		Contact Address
Permanent Address 31 Ganga Green City, Ganga Nagar, Meerut - 250001, Uttar Pradesh, India
Local Address DI/44 Birla Institute of Technology, Mesra, Ranchi - 835215, Jharkhand, India
Phone (Office) 06512276223
Phone Residence 9431184658
Email Id ssachan@bitmesra.ac.in
Joined Institute on : 12-Jul-2007
  Work Experience
 
Teaching : 16 Years

Research : 16 Years
  Research Areas
 
  • Microbial Biotransformation
  • Bioremediation
  Publications
 
  1. Hussain A, Ghosh Sachan S (2023) Fish Epidermal Mucus as a Source of Diverse Therapeutical Compounds International Journal of Peptide Research and Therapeutics doi.org/10.1007/s10989-023-10505-6
  2. Sunanda, Varsha, Prajakti, S. Chattopadhyay, S. Ghosh Sachan (2023) Biodegradation of polycyclic aromatic hydrocarbons and the impact of various genes for their enhanced degradation doi.org/10.1093/lambio/ovac062
  3. Sunanda, Ghosh Sachan S. (2023) Nanobioremediation of pesticides by immobilization technique: a review. International Journal of Environmental Science and Technology, 20: 3455-3466 doi.org/10.1007/s13762-021-03759-4
  4. Sunanda, Misra M, Ghosh Sachan S (2022) Nanobioremediation of heavy metals: Perspectives and challenges. Journal of Basic Microbiology, 62: 428-443 doi.org/10.1002/jobm.202100384 
  5. Singh A, Ghosh Sachan S, Mukhopadhyay K (2022) Enhanced vanillin production from eugenol by Bacillus cereus NCIM-5727 Bioprocess and Biosystems Engineering 45: 1811-1824
  6. Misra M, Chattopadhyay S, Sachan A, Ghosh Sachan S (2021) Microbially synthesized nanoparticles and their applications in environmental clean up, Environmental Technology Reviews DOI: 10.1080/21622515.2021.2011431
  7. Akansha K, Yadav AN, Kumar, M, Chakraborty D, Ghosh Sachan S. Decolorization and degradation of reactive orange 16 by Bacillus stratosphericus SCA1007. Folia Microbiologica (2021). doi.org/10.1007/s12223-021-00914-9
  8. Kumari R, Ghosh Sachan S, Sachan A (2021) Exploring triclosan degradation potential of Citrobacter freundii KS2003 International Journal of Environmental Science and Technology doi.org/10.1007/s13762-021-03305-2
  9. Sharma R, Ghosh Sachan S, Sharma SR (2020) In vitro analysis of gallstone formation in the presence of bacteria, Indian Journal of Gastroenterology 39: 473-480
  10. Singh A, Ghosh Sachan S, Mukhopadhyay K, Kumar M, Sachan A (2020) A rapid and simple ultra high performance liquid chromatography method for the simultaneous determination of methoxyphenol derivatives involved in the eugenol catabolic pathway, Journal of Separation Science 43:877-885
  11. Akansha K, Chakraborty D, Ghosh Sachan S (2019) Decolorization and degradation of methyl orange by Bacillus stratosphericus SCA1007, Biocatalysis and Agricultural Biotechnology 18: 101044
  12. Singh A, Mukhopadhyay K, Ghosh Sachan S (2018) Biotransformation of eugenol to vanillin by a novel strain Bacillus safensis SMS1003, Biocatalysis and Biotransformation, DOI: 10.1080/10242422.2018.1544245
  13. Kumari R, Ghosh Sachan S (2018) Bioconversion of toxic micropollutant triclosan to 2,4-dichlorophenol using a wastewater isolate Pseudomonas aeruginosa KS2002, International Journal of Environmental Science and Technology, DOI 10.1007/s13762-018-2129-5
  14. Kumar P, Kumari P, Ghosh Sachan S, Poddar R (2018) Mutational analysis of phenolic acid decarboxylase from Enterobacter sp. Px6-4. towards enhancement of binding affinity: A computational approach, Computational Biology and Chemistry 76: 245-255
  15. Kumar P, Ghosh Sachan S, Poddar R (2017) Mutational analysis of microbial hydroxycinnamoyl-CoA hydratase-lyase (HCHL) towards enhancement of binding affinity: A computational approach, Journal of Molecular Graphics and Modelling 77: 94-105.
  16. Yadav AN, Ghosh Sachan S, Verma P, Saxena AK (2016) Bioprospecting of plant growth promoting psychrotrophic Bacilli from cold desert of north western Indian Himalayas, Indian Journal of Experimental Biology 54: 142-150.
  17. Mishra S, Kullu M, Sachan A, Vidyarthi AS, Ghosh Sachan S (2016) Bioconversion of ferulic acid to vanillic acid by Paenibacillus lactis SAMS-2001, Annals of Microbiology DOI 10.1007/s13213-015-1175-1 2016,  66: 875-882.
  18. Yadav AN, Ghosh Sachan S, Verma P, Saxena AK (2015) Prospecting cold deserts of north western himalayas for microbial diversity and plant growth promoting attributes, Journal of Bioscience and Bioengineering 119: 683-393.
  19. Yadav AN, Ghosh Sachan S, Verma P, Kaushik R, Saxena AK (2015) Cold active hydrolytic enzymes production by psychrotrophic Bacilli isolated from three sub-glacial lakes of NW Indian Himalayas, Journal of Basic Microbiology 56: 294-307.
  20. Yadav AN, Ghosh Sachan S, Verma P, Saxena AK, Tyagi SP, Kaushik R (2015) Culturable diversity and functional annotation of psychrotrophic bacteria from cold desert of Leh Ladakh (India), World Journal of Microbiology and Biotechnology 31: 95-108. 
  21. Mishra A, Ghosh Sachan S, Pandey DM (2015) Maize Rhizosphere Microbial Population In Soils Of Jharkhand, International Journal Of Pharmacy And Pharmaceutical Sciences 7: 218-222.
  22. Sharma R, Soy S, Kumar C, Ghosh Sachan S, Sharma S R (2015) Analysis of gallstone composition and structure in Jharkhand region, Indian Journal of Gastroenterology 34: 29-37.
  23. Panjiar N, Ghosh Sachan S, Sachan A (2015) Screening of bioemulsifier producing microorganisms isolated from oil contaminated sites, Annals of Microbiology 65: 753-764.
  24. Mishra S, Sachan A, Vidyarthi AS, Ghosh Sachan S (2014) Microbial production of 4-vinyguaiacol from ferulic acid by Bacillus cereus SAS-3006, Biocatalysis and Biotransformation 32: 259-266
  25. Mishra S, Sachan A, Vidyarthi AS, Ghosh Sachan S (2014) Transformation of ferulic acid to 4-vinyl guaiacol as a major metabolite: a microbial approach, Reviews in Environmental Science and Bio/Technology 13: 377-385.
  26. Mishra S, Sachan A, Sachan Ghosh S (2013) Production of natural value-added compounds: An insight into eugenol biotransformation pathway, Journal of Industrial Microbiology and Biotechnology. 40: 545-550.
  27. Sachan A, Ghosh S, Mitra A (2010) Transforming p-coumaric acid into p-hydroxybenzoic acid by the mycelial culture of a white rot fungus Schizophyllum commune, African Journal of Microbiology Research 4: 267-273.
  28. Ghosh S, Sachan A, Sen S K, Mitra A (2007) Microbial transformation of ferulic acid to vanillic acid by Streptomyces sannanensis MTCC 6637, Journal of Industrial Microbiology and Biotechnology 34: 131-138.
  29. Sachan A, Ghosh S, Sen S K, Mitra A (2006) Co-production of caffeic acid and p-hydroxybenzoic acid from p-coumaric acid by Streptomyces caeruleus MTCC 6638, Applied Microbiology and Biotechnology 16: 1-8.
  30. Sachan A, Ghosh S, Mitra A (2006) Biotransformation of p-coumaric acid by Paecilomyces variotii, Letters in Applied Microbiology 42: 35-41.
  31. Ghosh S, Sachan A, Mitra A (2006) Formation of vanillic acid from ferulic acid by Paecilomyces variotii MTCC 6581, Current Science 90: 825-829.
  32. Mukherjee G, Sachan A, Ghosh S, Mitra A (2006) Conversion of sinapic acid to syringic acid by a filamentous fungus Paecilomyces variotii, Journal of General and Applied Microbiology 52:131-135.
  33. Ghosh S, Sachan A, Mitra A (2005) Degradation of ferulic acid by a basidiomycetes Schizophyllum commune, World Journal of Microbiology and Biotechnology 21: 385-388.
  34. Sachan A, Ghosh S, Mitra A (2004) An efficient isocratic separation of hydroxycinnamates and their corresponding benzoates from microbial and plant sources by high performance liquid chromatography, Biotechnology and Applied Biochemistry 40: 197-200.
  35. Dey G, Sachan A, Ghosh S, Mitra A (2003) Detection of major phenolic acids from dried mesocarpic husk of mature coconut by thin layer chromatography, Industrial Crops and Products 18: 171-1                                                                                                                                                                                                        Book Chapters

 

  1. Sunanda & Ghosh Sachan, S. (2023). Health impacts of pesticides on farm applicators. In: Current Developments in Biotechnology and Bioengineering, Pesticides: Human Health, Environmental Impacts and Management J. Singh, A. Pandey, S. Singh, V. K. Garg and P. C. Ramamurthy (eds.), Elsevier, 277-304. ISBN: 978-0-323-91900-5
  2. S. Pandey, I. Shreshtha, S. Ghosh Sachan (2021) Pullulan: Biosynthesis, production and applications. In: Microbial exopolysaccaharides as novel and significant biomaterials. AK Nadda et al (eds.), Springer Nature Switzerland AG e-ISBN: 978-3-030-75289-7
  3. M. Misra, A. Sachan and S. Ghosh Sachan (2021) Role of fungal endophytes in the green synthesis of nanoparticles and the mechanism In: Fungi Bio-Prospects in Sustainable Agriculture, Environment and Nano-technology Volume 3: Fungal Metabolites and Nano-technology. V. K. Sharma et al. (eds.), Academic Press, 489-504 ISBN: 978-0-12-821734-4
  4. M. Misra, S. Ghosh Sachan and S. Chattopadhyay (2021) Remediation of heavy metals from wastewater treatment plants using bacteria and algae In: New Trends in Removal of Heavy Metals from Industrial Wastewater. M. Shah et al. (eds.), Elsevier, 525-550 ISBN: 978-0-12-822965-1
  5. A. Hussain, R. Kumari, S. Ghosh Sachan and A. Sachan (2021) Biological wastewater treatment technology: Advancement and drawbacks In: Microbial Ecology of Wastewater Treatment Plants. M. Shah and S. Rodriguez-Couto (eds.), Elsevier, 175-190 ISBN: 978-0-12-822503-5
  6. P. Kumar and S. Ghosh Sachan (2021) Exploring microbes as bioremediation tools for the degradation of pesticides In: Advanced Oxidation Processes for Effluent Treatment plants. M. Shah (ed.), Elsevier, 51-67 ISBN: 978-0-12-821011-6
  7. P. Kumar, A. Singh, A. Sachan and S. Ghosh Sachan (2021) Molecular Tools for Microbial Diversity Analysis In: Wastewater Treatment Cutting-Edge Molecular Tools, Techniques and Applied Aspects. M. Shah et al. (eds.), Elsevier, 55-64 ISBN: 978-0-12-821881-5
  8. K. Akansha, S. Majumder, M. Misra and S. Ghosh Sachan (2021) Role of Microorganisms in Performance Optimization of Wastewater Treatment Plants In: Wastewater Treatment Cutting-Edge Molecular Tools, Techniques and Applied Aspects. M. Shah et al. (eds.), Elsevier, 67-87 ISBN: 978-0-12-821881-5
  9. M. Misra, A. Sachan, S. Ghosh Sachan (2020) Current Aspects and Applications of Biofertilizers for Sustainable Agriculture. In: Plant Microbiomes for Sustainable Agriculture, Sustainable Development and Biodiversity, A. N. Yadav et al. (eds.), Springer Nature Switzerland AG, ISBN 978-3-030-38452-4, e-ISBN 978-3-030-38453-1 
  10. M. Misra, K. Akansha, A. Sachan, S. Ghosh Sachan (2020) Removal of Dyes from Industrial Effluents by Application of Combined Biological and Physico-chemical Treatment Approaches In: Combined Application of Physico-Chemical & Microbiological Processes for Industrial Effluent Treatment Plant, M. Shah, A. Banerjee (eds.), Springer Nature Singapore, ISBN 978-981-15-0496-9, e-ISBN 978-981-15-0497-6 
  11. A Singh, R Kumari,  AN Yadav, S Mishra, A Sachan, S Ghosh Sachan (2020) Tiny Microbes, Big Yields: Microorganisms for Enhancing Food Crop Production Sustainable Development. In: Trends of Microbial Biotechnology for Sustainable Agriculture and Biomedicine Systems: Diversity and Functional Perspectives, Rastegari AA, Yadav AN, Yadav N (eds), Elsevier, USA , ISBN: 9780128205266 e-ISBN: 9780128205273
  12. R Kumari, A Singh, AN Yadav, S Mishra, A Sachan, S Ghosh Sachan (2020) Probiotics, prebiotics and synbiotics: Current status and future uses for human health. In: Trends of Microbial Biotechnology for Sustainable Agriculture and Biomedicine Systems: Perspectives for Human Health, Rastegari AA, Yadav AN, Yadav N (eds), Elsevier, USA , ISBN: 978-0-12-820528-0
  13. R Kumari, S Ghosh Sachan, A Sachan (2019) Environmental and Human Exposure to Antimicrobial Agent Triclosan: A Review. In: In vitro Plant Breeding towards Novel Agronomic Traits: Biotic and Abiotic Stress Tolerance, M Kumar et al (eds), Springer Nature Singapore Pte Ltd., ISBN 978-981-32-9824-8 (eBook)
  14. S Ghosh Sachan, A Sachan, A Mitra, S Mishra, M Kullu, A S Vidyarthi (2018) Production of natural vanilla from ferulic acid using biotransformation tools (2018) Recent advances in Microbiology Vol. III, NC Gautam et al. (eds.), Nova Science Publisher, USA,  ISBN: 978-1-53614-058-3
  15. AN Yadav, P Verma, S Ghosh Sachan, K Kaushik, AK Saxena (2018) Psychrotrophic Microbiome: Molecular Diversity and Beneficial Role in Plant Growth Promotion and Soil Health. In: Panpatte DG, Jhala YK, Shelat HN, Vyas RV (eds), Microorganisms for Green Revolution, Vol-2, Microbes for sustainable agro-ecosystem, Springer Singapore, Singapore, pp 197-240. Doi:10.1007/978-981-10-7146-1_11
  16. N Panjiar, S Ghosh Sachan, A Sachan (2017) Biosurfactants: A Multifunctional Microbial Metabolite. In: Microbial Applications Vol.2; pp. 213-229; Springer International Publishing AG 2017 V.C. Kalia (ed.), ISBN 978-3-319-52668-3, ISBN 978-3-319-52669-0 (eBook); DOI 10.1007/978-3-319-52669-0_12
  17. S Mishra, N Panjiar, A Sachan, AS Vidyarthi, S Ghosh Sachan (2017) Ferulic Acid Decarboxylase from Bacillus cereus SAS-3006: Purification and Properties. In: Applications of Biotechnology for Sustainable Development; pp. 169-179; SpringerNature; K. Mukhopadhyay et al. (eds.), ISBN 978-981-10-5537-9, ISBN 978-981-10-5538-6 (eBook); DOI 10.1007/978-981-10-5538-6_20
  18. N Panjiar, S Ghosh Sachan, A Sachan (2017) Biosurfactant production by Pseudomonas fluorescens NCIM 2100 forming Stable Oil-in-Water Emulsions. In: Applications of Biotechnology for Sustainable Development; pp. 97-107; SpringerNature; K. Mukhopadhyay et al. (eds.), ISBN 978-981-10-5537-9, ISBN 978-981-10-5538-6 (eBook); DOI 10.1007/978-981-10-5538-6_13
  19. A Mishra, S Ghosh Sachan, VK Nigam, DM Pandey (2016) Application of bioinformatics in biofertilizer technology. In: Recent Trends in Biofertilizers; pp. 146-154; IK International Publishing House Pvt. Ltd. BR Pati and SM Mandal (eds.) ISBN 978-93-84588-65-6

 

  1.   
  Member of Professional Bodies
 
  •  Life Member of The Indian Society for Technical Education, India
  • Life member of Association of Microbiologist, Mesra, India
  Current Sponsored Projects
 
  • Co-Principal Investigator: CSIR sponsored project ‘Bioprocess Development for efficient Triclosan Degradation’, July 2016-June 2019 (Completed)
  • Principal Investigator: DST-SERB sponsored project 'Biotransformation of eugenol into value-added methoxyphenols' , September 2014-March 2018 (Completed)
  • Bioremediation of synthetic dyes using microorganisms, Seed Money Scheme, BIT Mesra, November 2015-October 2016 (Completed)
  • Co-Developer: MHRD sponsored project ‘Developing suitable pedagogical methods for various classes, intellectual calibers and research in e-learning’ (National Mission Project on Education through ICT), Ministry of Human Resource Development Government of India & IIT, Kharagpur; Course name: Enzyme Technology, March 2009-March 2016 (Completed)
  • Principal Investigator: UGC-MRP sponsored project 'Production of natural flavour compounds from ferulic acid by microbial transformation'  February 2010-July 2013 (Completed)