Birla Institute of Technology, Mesra

Faculty Image

Dr. Shubha Rani Sharma

Joined Institute on : 1-Sep-2008

  • Assistant Professor
  • Bioengineering and Biotechnology
  • M.Sc., Ph.D.
Contact Address

Dept of Bioengineering & Biotechnology, BIT Mesra, Ranchi

4D, Kedar Enclave, Anantpur 1st street, Doranda, Ranchi

  • Phone Office - 9939139806
  • Phone Residence - 9835336661
  • Email - srsharma@bitmesra.ac.in
Work Experience

Teaching : 15 Years

Research : 17 Years

Professional Background

 

(i) Worked as Research Associate cum Tutor in Dept of Biotechnology, Birla Institute of Technology, Mesra, Ranchi for the period Sept 2008 – August 2009.

(ii) Worked as Scientist in Dept of Biotechnology, Birla Institute of Technology, Mesra, Ranchi for the period Sept 2009– Dec 2009.

(iii) Presently working as an Assistant Professor in Dept of Biotechnology, Birla Institute of Technology, Mesra, Ranchi from Jan 2010 till date.

Research Areas

Microbiology, Thermophiles, exopolysaccharides, Medical Microbiology, Gallstone & Gallbladder research, Microbiome research.

Award and Honours
  1. Selected in All India level Test Combined Entrance Examination (CEE) for M.Sc.  (Biotechnology) organized by Jawaharlal Nehru University, New Delhi.
  2. Department of Biotechnology (DBT) Scholarship (May 2000- 2002) awarded for pursuing Master’s     Program in Biotechnology.
  3. NET / JRF (CSIR) qualified in Dec 2002.
  4. 99.16 percentile score in GATE ( Graduate Aptitude Test In Engineering ) in 2003.
  5. Selected for PhD programme in Dept. of Biotechnology in IIT Kharagpur.
  6. Invited as a speaker at NIT Rourkela for National conference on Bioengineering (Bioengineering-2018),  December 14-15, 2018.
  7. Awarded International travel grant as a Speaker for KSBB-AFOB Conference 2025 , at South Korea (ROK) (23 September, 2025 to 27 September, 2025)" 
Publications
  1. Kumari N, Deb D, Sharma B, Sharma R, Sharma SR. Techniques for Gallstone Analysis: From Traditional Methods to Present Day Cutting-Edge Technologies- A Panoramic Review. Crit Rev Anal Chem. 2025 Nov 13:1-16. doi: 10.1080/10408347.2025.2586048. 
  2. Kaissar FZ, Bouacem K, Benine ML, Mechri S, Sharma SR, Singh VK, Bakli M, Lebouachera SEI, Emiliani G. Bacillus Pectinases as Key Biocatalysts for a Circular Bioeconomy: From Green Extraction to Process Optimization and Industrial Scale-Up. BioTech (Basel). 2025 Sep 19;14(3):74. doi: 10.3390/biotech14030074. 
  3. Karmakar, S., Beck, M. M., & Sharma, S. R. (2025). Exploring the Global Diversity of Biosurfactants Produced by Thermophilic Bacteria. Geomicrobiology Journal, 1–10. https://doi.org/10.1080/01490451.2025.2563881
  4. Sharma B, Shukla R, Nagar A, Ekka N, Kapoor VK, Behari A, Sharma SR. A comparative analysis of gallstones from gallbladder cancer patients and cholelithiasis patients unveiling the association between gallstones and gallbladder cancer. Med Oncol. 2025 Feb 4;42(3):65. doi: 10.1007/s12032-025-02614-7. [IF:2.8]
  5. Deo, R., Lakra, U., Ojha, M., Nigam, V. K., & Sharma, S. R. (2025). Exopolysaccharides in microbial interactions: signalling, quorum sensing, and community dynamics. Natural Product Research, 1–16. https://doi.org/10.1080/14786419.2024.2405867 [IF:1.9]
  6. Lakra, U., Kumar, V., Dhan, S., Nigam, V. K., & Sharma, S. R. (2024). Characterization and evaluation of biosurfactant produced from a thermophilc bacillus licheniformis. Bioremediation Journal, 29(1), 25-41. [IF:2.4]
  7. Lakra U, Lincoln Singh Munda V, Nigam VK, & Sharma SR (2023). Optimisation, characterization, and biological evaluation of novel exopolysaccharide from Bacillus licheniformis (BITSL006). Natural Product Research, 1–10. Advance online publication. https://doi.org/10.1080/14786419.2023.2265041 [IF: 2.5]
  8. Soy S, Lakra U, Prakash P, Suravajhala P, Nigam VK, Sharma SR, Bayal N. 2023. Exploring microbial diversity in hot springs of Surajkund, India through 16S rRNA analysis and thermozyme characterization from endogenous isolates. Scientific Reports 13,14221. [IF: 4.6]
  9. Lakra, Usha, and Shubha Rani Sharma. 2023, Production of exopolysaccharides from Bacillus licheniformis, a thermophilic bacterium from hot spring of Jharkhand. Natural Product Research, 1-10. [IF: 2.5]
  10. Soy S, Sharma SR & Nigam VK (2022) Bio-fabrication of thermozyme-based nano- biosensors: their components and present scenario. J Mater Sci: Mater Electron 33, 5523–5533. [IF:2.478]
  11. Snehi Soy, Vinod Kumar Nigam & Shubha Rani Sharma (2021) Enhanced production and biochemical characterization of a thermostable amylase from thermophilic bacterium Geobacillus icigianus BITSNS038, Journal of Taibah University for Science, 15:1, 730-745 [IF:2.688]
  12. Soy S, Nigam VK, Sharma SR2019. Cellulolytic, amylolytic and xylanolytic potential of thermophilic isolates of Surajkund hot spring. J Biosci 44:124. [IF-2.795]
  13. Sharma B, Sethi B, Kumar S, Poddar R, Prashad A, Sharma SR. Exploration of molecular interactions between Scoparone and associated compounds with Constitutive androstane receptor (CAR) leading to gallstone prevention: An In-silico investigation. Journal of Biomolecular Structure and Dynamics. 2023 42(2), 960–976. [IF: 5.235]
  14. Sharma B, Sharma SR. Evaluation of gallstone classification and their diagnosis through serum parameters as emerging tools in treatment: a narrative review. Postgraduate Medicine. 2022 Jul 29:1-0. [IF: 4.379]
  15. Sharma B, Sharma SR. Microstructural and heavy metal analysis of gallstones prevalent in Jharkhand and its implications in the treatment. Postgraduate Medicine. 2022 Nov 8:1-6. [IF:4.379]
  16. Kaur R, Arora N, Rawat SS, Keshri AK, Sharma SR, Mishra A, Singh G, Prasad A. Vaccine for a neglected tropical disease Taenia solium cysticercosis: fight for eradication against all odds. Expert Rev Vaccines. 2021 Nov; 20(11):1447-1458. doi: 10.1080/14760584.2021.1967750. [IF- 5.683]
  17. Rajani Sharma, Shashwati Ghosh Sachan & Shubha Rani Sharma, 2020, In vitro analysis of gallstone formation in the presence of bacteria, Indian J Gastroenterol. 39(5):473-480. [IF: 2]
  18. Rajani Sharma, Snehi Soy, Chandan Kumar, Shashwati Ghosh Sachan & Shubha Rani Sharma, 2015, “Analysis of gallstone composition and structure in Jharkhand region,” Indian J Gastroenterol. 34(1), 29-37. Scopus
  19. Rajani Sharma, Ujwal Kumar, Nawal Kishore Jha, Shashwati Ghosh Sachan and Shubha Rani Sharma, 2014, “Consumption of heme iron: A major factor in pigment gallstone formation”, IJBR, 5 (01), 34-37.
  20. Rajani Sharma, Shashwati Ghosh Sachan, Shubha Rani Sharma, 2014, “Preponderance of gallstones in females”, WJPPS 2(6), 5871-5877.
  21. Rajani Sharma, Shashwati Ghosh Sachan, Shubha Rani Sharma, 2013, “Urease Positive and Slime Producing Bacterial Activity: Results in Gallstone Precipitation and Solidification”, Arch Clin Infect Dis. (4): e17090. Scopus
  22. Rajani Sharma, Ansul Kumar, Nawal Kishore Jha, Shashwati Ghosh Sacchan, Ambrish Sharan Vidyarthi, Shubha Rani Sharma, 2012, “Probing into the prevalence and factors of gallstones formation in Jharkhand region in India” IJABPT, 3(3):36-41.
  23. Shamim Nezami, Katrin Joseph, Anam Ahsan, LVS Aparna, Shubha Rani Sharma, Santosh Kumar  Jha, 2016.  Screening of commercially important halophilic microbial community for bioactive compounds. IJPCBS, 6(3): 309-321.
  24. Kartar Singh, Milli Ghosh, Shubha Rani Sharma (2015), Water surface boundary detection algorithm using landsat 8 OLI Data, IEEE J. Sel. Topics Appl. Earth Observ. in Remote Sens, 9: 363-368 [IF: 4.715]
  25. Kartar Singh, Milli Ghosh, Shubha Rani Sharma, Pawan Kumar, (2014) Blue-red-NIR model for chlorophyll- retrieval in hypersaline-alkaline water using landsat ETM+ sensor, IEEE J. Sel. Topics Appl. Earth Observ. in Remote Sens, 7: 3553-3559 [IF: 4.715]
  26. Poddar R, Sharma SR, Andrews JT, & Sen P (2008). Correlation between glucose concentration and reduced scattering coefficients in turbid media using optical coherence tomography. Current Science, 95(3), 340–344. [IF: 1.169]
  27. Raju Poddar, S. R. Sharma, K. Bose, P. Sen and J. T. Andrews, A Study of Longitudinal Laser Modes of a Semiconductor Laser Using Optical Coherence Tomography, American Journal of Physics, 2006, Vol. 74 (7), 569-571, 2006. [IF: 0.835]
  28. Raju Poddar, Shubha R. Sharma, Pratima Sen and J. T. Andrews, Effect of glucose concentration on scattering coefficients in blood like Turbid Media using diffuse reflectance, International Journal of Biotechnology & Biochemistry (IJBB), Vol. 2 (1), 34 – 40, 2006.
  29. S.R Sharma, Raju Poddar P. Sen and J.T. Andrews, Effect of Vitamin C on Collagen biosynthesis and degree of Birefringence measurements using Polarization sensitive optical coherence tomography (PS-OCT), African Journal of Biotechnology, Vol. 7 (12), 2049-2054, 2007.
Member of Professional Bodies

Life Member of Association of Microbiologist, India(AMI)

Life Member of BSRI, India

Current Sponsored Projects
  1. Received a CSIR project in June 2023, entitled “Optimization of Production and Commercial Application of Xylanase from Thermophilic Bacteria of Surajkund Hotspring” with Sanction No. 60/125/23/EMR-II for a period of 3 years as PI.
  2. Received an Indo Japan Project funded by Japanese funding Agency JSPS in March 2024, entitledThe role of oxysterol in gallbladder cancer development” with Grant Number 23KK0715. for a period of 4 years as Indian PI.
  3. Received a Council of Science, Technology & Innovation (Dept of Higher & Technical Education), Jharkhand project in June 2025, entitledDesigning of drinking water system for the removal of groundwater fluoride using biochar derived from agro-industrial wastefor a period of 2 years as Co-PI.
  4. Received a Council of Science, Technology & Innovation (Dept of Higher & Technical Education), Jharkhand project in June 2025, entitledDevelopment of microbial biosurfactant based formulations as means of bioremediation and protection against phytopathogen of paddy in Jharkhandfor a period of 2 years as Co-PI. 
Text and Reference Books

Book:

Gallstone Formation, Diagnosis, Treatment and Prevention: 1st Edition - April 1, 2024 Editors: Rajani Sharma, Shubha Rani Sharma, Ram Prasad.  Paperback ISBN: 9780443160981

Book Chapters : 

 

S.No.

Title

Author’s Name

Publisher

Year of Publication

Citations

1.

Case study of gallbladder diseases and microbiome

Chinmay Patade, Bhavna Sharma, Sneha Kumari, Rajani Sharma, Shubha Rani Sharma

Academic Press

2025

 

2.

Historic perspective of gallstones

Bhavna Sharma, Rajani Sharma, Ram Prasad, Shubha Rani Sharma

Academic Press

Elsevier

2024

 

3.

Orchestration of the Plant Microbiome for Enhanced Agriculture In

book: Sustainable Agriculture Reviews 60, Microbial Processes in Agriculture

Sharma S and Sharma R

Springer Nature

2023

 

4.

A comprehensive review on nanopesticides and nanofertilizers—A boon for agriculture

Bhavna Sharma, Usha Lakra, Rajani Sharma, Shubha Rani Sharma

Academic Press

2022

1

5.

Conducting Polymers as Efficient Materials for Tissue Engineering

Srijita Sen, Trishna Bal, Aditya Dev Rajora, Shreya Sharma, Shubha Rani Sharma, Neelima Sharma

CRC press

2022

-

6.

Microbial Aspect in Wastewater Management: Biofilm.

Sharma R., Sharma S.R.

Springer

2022

-

7.

An Insight into Nanosomes: Potential Nanopharmaceutical Delivery System. In Nanopharmaceutical Advanced Delivery Systems

Trishna, B., Sandeep, G., Rajora, A.D., Sharma, S.R. and Hars, H.

Wiley

2021

-

8.

Novel Microbial Compounds as a Boon in Health Management

Shubha Rani Sharma, Rajani Sharma, and Debasish Kar

CRC Press

2020

-

9.

An Insight into Plant Nanobionics and Its Applications

Sharma S.R., Kar D.

Springer

2019

3

10.

Fungal-Mediated Solid Waste Management: A Review.

Jain A, Yadav S, Nigam VK, Sharma SR

Springer

2018

5

11.

Bioremediation of Polythenes and Plastics: A Microbial Approach

Sharma SR 

Springer

2018

12

12.

Application of matrices for the development of next-gen bioreactors from COVID-19 waste management prospects.

Soy S., Kapoor B., Sharma S & Nigam V.

Elsevier

2022

 

13.

Analysis of emerging microbial contaminants through next-generation sequencing

 

Shubha Rani SharmaAvinash SinghNeha SinghAmit PrasadVinod Kumar Nigam

Taylor & Francis

2021

 

14.

Remote Sensing-Based Estimation of Shallow Inland Lake Morphometry: A Case Study of Sambhar Salt Lake, Ramsar Site-464, India

 

Singh K, Lala MGN, Sharma SR, Ashutosh, Chandra G, Prakash A

Springer

2022

 

 

 

Intellectual Property Rights (IPR)

 

S. No.

Inventors and Title

Number and Date

Published/

Granted

1.

A method for efficient production of microbial natural product for wound care

Application no.: 202331081605, Ref. :PAT199/045/23

Published

2.

A method for time-efficient production of microbial natural product using minimal media         

Application no.: 202431002003,

Ref.: PAT199/083/23

Published

Member, Editorial Board