• Professor (Since August 2021), Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India
• Associate Professor (July 2016 to August 2021), Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India
• Assistant Professor (Jun 2007 to June 2016), Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India 
• Lecturer (Feb 2004 to May 2007), Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India 
• Assistant Professor (Jul 2002 to Jan 2004), Sanjivani College of Pharmaceutical Sciences, Ketri-333503 (RJ), India 
• Assistant Professor (Apr 1999 to Jun 2002), JKKMMRF College of Pharmacy, Komarapalayam-638183 (TN), India
• Tutor (Nov 1996 to Aug 1997), JKKMMRF College of Pharmacy, Komarapalayam-638183 (TN), India

Expertise

• Organic Synthesis and Medicinal Chemistry
• Molecular Modeling and Drug Design

Research Area:

• Antitubercular: Mycobactin bioynthesis inhibitors
• CNS: Monoamine oxidase inhibitors
• Anticancer: HDAC inhibitors, RR inhibitors, CDK inhibitors & CYP inhibitors
• Antivirals: Protease inhibitors (DenV & ChikV) , Fusion inhibitors (DenV)  

• 1997-1999, Junior Research Fellowship, University Grants Commission, Government of India
• 2015, Travel Grant from DBT (DBT/CTEP/02/201501300)- "International Multidisciplinary Symposium on Drug Research and Development" organized by Anadolu University Ataturk Culture & Arts Centre, Eskisehir, Turkey, 15-17 October, 2015 

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• Registered Pharmacist (17905 A2), Tamilnadu Pharmacy Council, Vadapalani, Chennai-600026 (TN), India
• APTI Life Member (TN/LM-187), H.Q: No.620 D, 35th Cross, 2nd Block, Rajajinagar, Bengaluru-560 010 (KA), India

Co-Principal Investigator

Title: Aptamer-based Diagnostic Kit for Detection of Corona Virus Infection (CoVapt)

Scheme & Agency: Science & Engineering Research Board, DST,  Govt. of India, India

File No.: CVD/2020/000311 dt. 17th July 2020

Amount Sanctioned: 15,74,672/-

Duration: One year (2020-2021)

Principal Investigator

Scheme & Agency: Newton Bhabha PhD Placement Programme (2019-2020), Department of Biotechnlogy (DBT), Govt of India, India

File No.: BT/IN/NBPP/20/2019-20 dt. 4th March 2020

Amount Sanctioned: 17,38,235/-

Duration: Four Months (2020-2021)

Principal Investigator

Title: Design & Development of Inhibitors of DENV Methyltransferase for the Treatment of Dengue Viral Infection

Scheme & Agency: Research Promotion Scheme (RPS), All India Council for Technical Education (AICTE), Govt of India, India

File No.: 8-70/RIFD/RPS/POICY-1/2016-17 dt. 4th August 2017

Amount Sanctioned: 17,38,235/-

Duration: Three years (2017-2020)

Co-Principal Investigator

Title: Design and Synthesis of Substrate Based Peptide Inhibitors of DENV Protease for the Treatment of Dengue Viral Infections

Principal Investigator: Dr. Barij Nayan Sinha & Co-Principal Investigator: Dr. B. Sarkar

Scheme & Agency: EMR (Individual Centric), Science & Engineering Research Board, DST,  Govt. of India, India

File No.: EMR/2016/005711

Amount Sanctioned: 45,60,400/-

Duration: Three years (2017-2020)

Principal Investigator

Title: Phenyloxazoline Synthetase Inhibitors as Antitubercular Agents (POSIAA)

Co-Principal Investigator: Dr. Abhimanyu Dev

Scheme & Agency: EMR (Individual Centric), Science & Engineering Research Board, DST,  Govt. of India, India

File No.: EMR/2016/000675

Amount Sanctioned: 53,73,450/-

Duration: Three years (2016-2019)

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Design & Synthesis of potent dual inhibitors of Cdk-4 and tubulin as anticancer agents

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: An Indo-UK Project sponsored by University Grants Commission (UGC), Govt. of India, India

Amount Sanctioned: 30,88,800/-

Duration: Two years (2013-2015)

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Structure-based discovery of antivirals for the treatment of Chikungunya virus infections (Anti-Chick)

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: New-Indigo Eranet, An Indo-German Project sponsored by Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India

Amount Sanctioned: 34,62,000/-

Duration: (Two Years) 2011-2013

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Structure-based design of Dengue virus protease inhibitors

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: An Indo-German Project sponsored by Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India

Amount Sanctioned: 24,51,800/-

Duration: (3 Years) 2011-2014

Co-principle Investigator

Title: Grid-based Virtual Screening for TB (Grid-ViSiT)

Principle Investigator: K. K. Patnaik, Dept. of Comp. Sci. Engg., BIT, Mesra

Scheme & Agency: Research Promotion Scheme (RPS) sponsored by All IndiaCouncil for Technical Education (AICTE), Govt. of India, India

Amount Sanctioned: Rs. 6,50,000/-

Duration: (Two Years) 2008-2010

Book

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents, Edited by Venkatesan Jayaprakash, Daniele Castagnolo, Yusuf Ozkat, CRC Press, 2019 (ISBN: 978-1138541245)

Venkatesan Jayaprakash, Barij Nayan Sinha, Anti-tubercular Drug Design Exploring Mycobactin Biosynthetic Pathway, Designing molecules that mimics hydroxyphenyl oxazoline portion of mycobactin, LAP Lambert Academic Publication, Germany, 2013 (ISBN:978-3-659-43995-7)

Book Chapter

Venkatesan Jayaprakash, Ajay Kumar Timiri, Barij Nayan Sinha, "Studies on Inhibitors of Dengue Virus Protease", Advances in Studies on Enzyme Inhibitors As Drugs: Anticancer and Antiviral Drugs, Vol. I, Editor, S. P. Gupta, Nova Science Publisher Inc., New York, 2017(ISBN:978-1-53610-504-9)

GRANTED

• Indian Patent No. 455777 - Title: 3-(2-hydroxyphenyl)-5-phenyl-4, 5-dihydro-1h-pyrazole derivatives, and method of preparing the same3-(2-hydroxyphenyl)-5-phenyl-4, 5-dihydro-1h-pyrazole derivatives, and method of preparing the same

PUBLISHED

• Application No. 325/KOL/2014 A; Title: 2-(4,6-diaminopyrimidin-2-ylthio)-N-aryl acetamide derivatives, their synthesis, antiviral activity and methods thereof
• Application No. 191/KOL/2014 A; Title: 4-(1,3-dioxoisoindolin-2-yl)-benzenesulfonamide derivatives, their synthesis, antiviral activity and methods thereof
• Application No. 811/KOL/2013; Title: Arylmethylidene heterocyclics as novel antiviral agents against chikungunya viral infection
• Application No. 349/CHE/2011; Title: Dihydropyrimidine Derivatives as pharmacologically active agents

Editor: Journal of Pharmaceutical Chemistry (eISSN: 2349-5731)

Associate Editor: Frontiers in Antibiotic: Antibiotic Development (eISSN: 2813-2467)

Editorial Board Member: PHARMBIT (ISSN: 0973-6204)