Birla Institute of Technology, Mesra
   
Venkatesan Jayaprakash PhD
Associate Professor, Pharmaceutical Sciences and Tech
M. Pharm., Ph.D.
Contact Address
Permanent Address 26/46, Ragavendra Street, Komarapalayam, Namakkal-638183 (TN) India
Local Address DI/29, Inner Campus, Birla Institute of Technology, Mesra, Ranchi-835215 (JH) India
Phone (Office) 2275290
Phone Residence 0651-2275555
Email Id venkatesanj@bitmesra.ac.in
Joined Institute on : 16-Feb-2004
  Work Experience
 
Teaching : 20 Years

Research : 16 Years

  Professional Background
  • Associate Professor (Since July 2016), Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India
  • Assistant Professor (Jun 2007 to June 2016), Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India 
  • Lecturer (Feb 2004 to May 2007), Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India 
  • Assisstant Professor (Jul 2002 to Jan 2004), Sanjivani College of Pharmaceutical Sciences, Ketri-333503 (RJ), India 
  • Assistant Professor (Apr 1999 to Jun 2002), JKKMMRF College of Pharmacy, Komarapalayam-638183 (TN), India
  • Tutor (Nov 1996 to Aug 1997), JKKMMRF College of Pharmacy, Komarapalayam-638183 (TN), India
  Research Areas
 

Expertise

  • Organic Synthesis and Medicinal Chemistry
  • Molecular Modeling and Drug Design

Research Area:

  • Antitubercular: Mycobactin bioynthesis inhibitors
  • CNS: Monoamine oxidase inhibitors
  • Anticancer: HDAC inhibitors, RR inhibitors, CDK inhibitors & CYP inhibitors
  • Antivirals: Protease inhibitors (DenV & ChikV) , Fusion inhibitors (DenV)  
  Award and Honours
 
  • 1997-1999, Junior Research Fellowship, University Grants Commission, Government of India
  • 2015, Travel Grant from DBT (DBT/CTEP/02/201501300)- "International Multidisciplinary Symposium on Drug Research and Development" organized by Anadolu University Ataturk Culture & Arts Centre, Eskisehir, Turkey, 15-17 October, 2015 
   Publications
 
Scopus
Scopus Author ID: 23995556000
EXPORT DATE:24 Jan 2021
ORCID: http://orcid.org/0000-0002-9724-4153

h-index: 23

Jana, P., Shyam, M., Singh, S., Jayaprakash, V., Dev, A.
Biodegradable polymers in drug delivery and oral vaccination
(2021) European Polymer Journal, 142, art. no. 110155, . 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096819580&doi=10.1016%2fj.eurpolymj.2020.110155&partnerID=40&md5=c1ab3bf87fba53e5684a250f5d59ad49

DOI: 10.1016/j.eurpolymj.2020.110155
ISSN: 00143057
CODEN: EUPJA

Mary, S.J.J., Siddique, M.U.M., Pradhan, S., Jayaprakash, V., James, C.
Quantum chemical insight into molecular structure, NBO analysis of the hydrogen-bonded interactions, spectroscopic (FT–IR, FT–Raman), drug likeness and molecular docking of the novel anti COVID-19 molecule 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide - dimer
(2021) Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 244, art. no. 118825, . Cited 3 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089907515&doi=10.1016%2fj.saa.2020.118825&partnerID=40&md5=7644506eb1462a3fec89fa38a8099b85

DOI: 10.1016/j.saa.2020.118825
ISSN: 13861425
CODEN: SAMCA

Brucoli, F., Bhakta, S., Jayaprakash, V., Shyam, M., Shilkar, D., Verma, H., Dev, A., Sinha, B.N.
The mycobactin biosynthesis pathway: A prospective therapeutic target in the battle against tuberculosis
(2021) Journal of Medicinal Chemistry, . 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099111485&doi=10.1021%2facs.jmedchem.0c01176&partnerID=40&md5=607ef4c80847a87c80db87aedcba7764

DOI: 10.1021/acs.jmedchem.0c01176
ISSN: 00222623
CODEN: JMCMA

Siddique, M.U.M., Ansari, A., Sinha, B.N., Jayaprakash, V.
Comparative Computational Studies on Selective CytochromeP450 1B1 Inhibitors
(2020) International Journal Bioautomation, 24 (3), pp. 213-224. 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098881434&doi=10.7546%2fIJBA.2020.24.3.000537&partnerID=40&md5=7f7e590b564164a3fd7addea01ab11cb

DOI: 10.7546/IJBA.2020.24.3.000537
ISSN: 13141902

Jadav, S.S., Badavath, V.N., Ganesan, R., Ganta, N.M., Besson, D., Jayaprakash, V.
Biological evaluation of 2-aminothiazole hybrid as antimalarial and antitrypanosomal agents: Design and synthesis
(2020) Anti-Infective Agents, 18 (2), pp. 101-108. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086321572&doi=10.2174%2f2211352516666181016122537&partnerID=40&md5=2842333e3c84c0e9c29ff1a12bb0a292

DOI: 10.2174/2211352516666181016122537
ISSN: 22113525

Bose, P., Siddique, M.U.M., Acharya, R., Jayaprakash, V., Sinha, B.N., Lapenna, A., Pattanayak, S.P.
Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway
(2020) Clinical and Experimental Pharmacology and Physiology, 47 (1), pp. 143-157. Cited 3 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074574552&doi=10.1111%2f1440-1681.13184&partnerID=40&md5=f4f0ca2cbe2d57a0d2e97ca7588a3522

DOI: 10.1111/1440-1681.13184
ISSN: 03051870
CODEN: CEXPB

Yasmin, S., Cerchia, C., Badavath, V.N., Laghezza, A., Dal Piaz, F., Mondal, S.K., Atl?, Ö., Baysal, M., Vadivelan, S., Shankar, S., Siddique, M.U.M., Pattnaik, A.K., Singh, R.P., Loiodice, F., Jayaprakash, V., Lavecchia, A.
A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects
(2020) ChemMedChem, . 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094201128&doi=10.1002%2fcmdc.202000564&partnerID=40&md5=ce11c2c13350dca05ff9649f4bda1f9a

DOI: 10.1002/cmdc.202000564
ISSN: 18607179
CODEN: CHEMG

Sonawane, V.R., Siddique, M.U.M., Gatchie, L., Williams, I.S., Bharate, S.B., Jayaprakash, V., Sinha, B.N., Chaudhuri, B.
Corrigendum to “CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance” (European Journal of Pharmaceutical Sciences (2019) 131 (177–194), (S0928098719300697), (10.1016/j.ejps.2019.02.016))
(2019) European Journal of Pharmaceutical Sciences, 136, art. no. 104960, . 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067510909&doi=10.1016%2fj.ejps.2019.104960&partnerID=40&md5=2936f0f036ced26a7d8012b7a7040f4a

DOI: 10.1016/j.ejps.2019.104960
ISSN: 09280987
CODEN: EPSCE

Abdelnabi, R., Geraets, J.A., Ma, Y., Mirabelli, C., Flatt, J.W., Domanska, A., Delang, L., Jochmans, D., Kumar, T.A., Jayaprakash, V., Sinha, B.N., Leyssen, P., Butcher, S.J., Neyts, J.
A novel druggable interprotomer pocket in the capsid of rhino-and enteroviruses
(2019) PLoS Biology, 17 (6), art. no. e3000281, . Cited 11 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067818589&doi=10.1371%2fjournal.pbio.3000281&partnerID=40&md5=f1ef2f8cd91ad35bc1feb427f96364d9

DOI: 10.1371/journal.pbio.3000281
ISSN: 15449173
CODEN: PBLIB

Sonawane, V.R., Siddique, M.U.M., Gatchie, L., Williams, I.S., Bharate, S.B., Jayaprakash, V., Sinha, B.N., Chaudhuri, B.
CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance
(2019) European Journal of Pharmaceutical Sciences, 131, pp. 177-194. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061959780&doi=10.1016%2fj.ejps.2019.02.016&partnerID=40&md5=cea0d75ff0f6baf0f2aadeeb1e1d2803

DOI: 10.1016/j.ejps.2019.02.016
ISSN: 09280987
CODEN: EPSCE

Sonawane, V., Mohd Siddique, M.U., Jadav, S.S., Sinha, B.N., Jayaprakash, V., Chaudhuri, B.
Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy
(2019) European Journal of Medicinal Chemistry, 165, pp. 115-132. Cited 8 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060116430&doi=10.1016%2fj.ejmech.2019.01.011&partnerID=40&md5=d486c0671004870f13cad8d25305e663

DOI: 10.1016/j.ejmech.2019.01.011
ISSN: 02235234
CODEN: EJMCA

Mohd Siddique, M.U., Barbhuiya, T.K., Sinha, B.N., Jayaprakash, V.
Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1
(2019) European Journal of Medicinal Chemistry, 163, pp. 28-36. Cited 3 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057327708&doi=10.1016%2fj.ejmech.2018.11.039&partnerID=40&md5=7af5488ab12303e79ed6f0306dab0019

DOI: 10.1016/j.ejmech.2018.11.039
ISSN: 02235234
CODEN: EJMCA

Shyam, M., Dev, A., Sinha, B.N., Jayaprakash, V.
Scaffold based search on the desferithiocin archetype
(2019) Mini-Reviews in Medicinal Chemistry, 19 (19), pp. 1564-1576. 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076337412&doi=10.2174%2f1389557519666190301151151&partnerID=40&md5=5d33a775424a221a1ac0d1eb4e3eff9d

DOI: 10.2174/1389557519666190301151151
ISSN: 13895575
CODEN: MMCIA

Molla, A., Ranjan, S., Rao, M.S., Dar, A.H., Shyam, M., Jayaprakash, V., Hussain, S.
Borax Catalysed Domino Synthesis of Highly Functionalised Spirooxindole and Chromenopyridine Derivatives: X-Ray Structure, Hirshfeld Surface Analysis and Molecular Docking Studies
(2018) ChemistrySelect, 3 (30), pp. 8669-8677. Cited 8 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051709266&doi=10.1002%2fslct.201801867&partnerID=40&md5=66a48c787691c4a4e74459514b70bb7c

DOI: 10.1002/slct.201801867
ISSN: 23656549

Siddique, M.U.M., Sinha, B.N., Jayaprakash, V.
Comparative shape and electrostatic study of highly potent and selective CYP1B1 inhibitor: Assessment of active site of CYP1B1 by binding mode analysis using site map tool
(2018) Indian Journal of Pharmaceutical Education and Research, 52 (1), pp. 159-165. 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047495474&doi=10.5530%2fijper.52.1.18&partnerID=40&md5=21eb753da35986193a644b19a753ab91

DOI: 10.5530/ijper.52.1.18
ISSN: 00195464

Bagchi, S., Rathee, P., Jayaprakash, V., Banerjee, S.
Farnesyl transferase inhibitors as potential anticancer agents
(2018) Mini-Reviews in Medicinal Chemistry, 18 (19), pp. 1611-1623. Cited 11 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055202698&doi=10.2174%2f1389557518666180801110342&partnerID=40&md5=9cfe378cb13d6ff0d15399172d9a9831

DOI: 10.2174/1389557518666180801110342
ISSN: 13895575
CODEN: MMCIA

Choudhury, M., Viswanathan, V., Timiri, A.K., Sinha, B.N., Jayaprakash, V., Velmurugan, D.
Crystal structures and Hirshfeld surface analyses of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]- N -(pyridin-2-yl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]- N -(pyrazin-2-yl)acetamide
(2018) Acta Crystallographica Section E: Crystallographic Communications, 74, pp. 718-723. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046728109&doi=10.1107%2fS2056989018005704&partnerID=40&md5=19afe7a1e0d9bb88de5cdacfbb35af50

DOI: 10.1107/S2056989018005704
ISSN: 20569890

Nath, C., Badavath, V.N., Thakur, A., Ucar, G., Acevedo, O., Mohd Siddique, M.U., Jayaprakash, V.
Curcumin-based pyrazoline analogues as selective inhibitors of human monoamine oxidase A
(2018) MedChemComm, 9 (7), pp. 1164-1171. Cited 13 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050517566&doi=10.1039%2fc8md00196k&partnerID=40&md5=825007b32887e2e6c43a04947101fede

DOI: 10.1039/c8md00196k
ISSN: 20402503
CODEN: MCCEA

Jadav, S.S., Sinha, B.N., Hilgenfeld, R., Jayaprakash, V.
Computer-aided structure based drug design approaches for the discovery of new anti-CHIKV agents
(2017) Current Computer-Aided Drug Design, 13 (4), pp. 346-361. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038628214&doi=10.2174%2f1573409913666170309145308&partnerID=40&md5=a8b830e588d0f1f4af66248e3215427e

DOI: 10.2174/1573409913666170309145308
ISSN: 15734099

Yasmin, S., Capone, F., Laghezza, A., Piaz, F.D., Loiodice, F., Vijayan, V., Devadasan, V., Mondal, S.K., Atll, Ö., Baysal, M., Pattnaik, A.K., Jayaprakash, V., Lavecchia, A.
Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes
(2017) Scientific Reports, 7 (1), art. no. 14453, . Cited 12 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032638225&doi=10.1038%2fs41598-017-14776-0&partnerID=40&md5=80e1ca6c281f0e4237c1f9a9ef49ae54

DOI: 10.1038/s41598-017-14776-0
ISSN: 20452322

Graser-Loescher, G., Schoenhuber, A., Ciglenec, C., Eberl, S., Krupitza, G., Mader, R.M., Jadav, S.S., Jayaprakash, V., Fritzer-Szekeres, M., Szekeres, T., Saiko, P.
Thiosemicarbazone derivatives, thiazolyl hydrazones, effectively inhibit leukemic tumor cell growth: Down-regulation of ribonucleotide reductase activity and synergism with arabinofuranosylcytosine
(2017) Food and Chemical Toxicology, 108, pp. 53-62. Cited 5 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85025589698&doi=10.1016%2fj.fct.2017.07.029&partnerID=40&md5=cc71849765b2fc34d2678a5f96a62d6e

DOI: 10.1016/j.fct.2017.07.029
ISSN: 02786915
CODEN: FCTOD

Yasmin, S., Jayaprakash, V.
Thiazolidinediones and PPAR orchestra as antidiabetic agents: From past to present
(2017) European Journal of Medicinal Chemistry, 126, pp. 879-893. Cited 31 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006054934&doi=10.1016%2fj.ejmech.2016.12.020&partnerID=40&md5=48c94c2d22d56fc4fa4920d6577ade45

DOI: 10.1016/j.ejmech.2016.12.020
ISSN: 02235234
CODEN: EJMCA

Choudhury, M., Viswanathan, V., Timiri, A.K., Sinha, B.N., Jayaprakash, V., Velmurugan, D.
Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(2,4-dimethylphenyl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(3-methoxyphenyl)acetamide Choudhury Manisha
(2017) Acta Crystallographica Section E: Crystallographic Communications, 73, pp. 996-1000. Cited 3 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85023192428&doi=10.1107%2fS2056989017008143&partnerID=40&md5=1ebde24eeb62f45b30771e787c73911f

DOI: 10.1107/S2056989017008143
ISSN: 20569890

Badavath, V.N., Nath, C., Ganta, N.M., Ucar, G., Sinha, B.N., Jayaprakash, V.
Design, synthesis and MAO inhibitory activity of 2-(arylmethylidene)-2,3-dihydro-1-benzofuran-3-one derivatives
(2017) Chinese Chemical Letters, 28 (7), pp. 1528-1532. Cited 13 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017447980&doi=10.1016%2fj.cclet.2017.02.009&partnerID=40&md5=e7697d27d879104c651603d8c19976c6

DOI: 10.1016/j.cclet.2017.02.009
ISSN: 10018417
CODEN: CCLEE

Subasri, S., Kumar, T.A., Sinha, B.N., Jayaprakash, V., Viswanathan, V., Velmurugan, D.
Crystal structures of N-(4-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide and N-(3-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide
(2017) Acta Crystallographica Section E: Crystallographic Communications, 73, pp. 467-471. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017322361&doi=10.1107%2fS2056989017003243&partnerID=40&md5=7ce94a54e5606bed3fd923ea8586252a

DOI: 10.1107/S2056989017003243
ISSN: 20569890

Subasri, S., Kumar, T.A., Sinha, B.N., Jayaprakash, V., Viswanathan, V., Velmurugan, D.
Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(naphthalen-1-yl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide
(2017) Acta Crystallographica Section E: Crystallographic Communications, 73, pp. 306-309. Cited 2 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011593492&doi=10.1107%2fS2056989017001293&partnerID=40&md5=2da48eb87f3f3aa2f86ac5659b6a8c5a

DOI: 10.1107/S2056989017001293
ISSN: 20569890

Kasthuri, J.K., Singh Jadav, S., Thripuram, V.D., Gundabolu, U.R., Ala, V.B., Kolla, J.N., Jayaprakash, V., Ahsan, M.J., Bollikolla, H.B.
Synthesis, Characterization, Docking and Study of Inhibitory Action of Some Novel C-Alkylated Chalcones on 5-LOX Enzyme
(2017) ChemistrySelect, 2 (28), pp. 8771-8778. Cited 3 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041833046&doi=10.1002%2fslct.201700517&partnerID=40&md5=7672d87bc53e298bcf65d4ce3f2d2fb3

DOI: 10.1002/slct.201700517
ISSN: 23656549

Mohd Siddique, M.U., McCann, G.J.P., Sonawane, V.R., Horley, N., Gatchie, L., Joshi, P., Bharate, S.B., Jayaprakash, V., Sinha, B.N., Chaudhuri, B.
Quinazoline derivatives as selective CYP1B1 inhibitors
(2017) European Journal of Medicinal Chemistry, 130, pp. 320-327. Cited 24 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014286174&doi=10.1016%2fj.ejmech.2017.02.032&partnerID=40&md5=c841e3f8f5ebf7f1418d411b590e3fe5

DOI: 10.1016/j.ejmech.2017.02.032
ISSN: 02235234
CODEN: EJMCA

Badavath, V.N., Jadav, S.S., Pastorino, B., De Lamballerie, X., Sinha, B.N., Jayaprakash, V.
Synthesis and antiviral activity of 2-aryl-4H-chromen-4-one derivatives against Chikungunya virus
(2016) Letters in Drug Design and Discovery, 13 (10), pp. 1019-1024. Cited 7 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995900405&doi=10.2174%2f1570180813666160711163349&partnerID=40&md5=b77a4230865831d3b528e62e34e166ea

DOI: 10.2174/1570180813666160711163349
ISSN: 15701808
CODEN: LDDDA

Mule, S.N.R., Nurbhasha, S., Kolla, J.N., Jadav, S.S., Jayaprakash, V., Bhavanam, L.R., Bollikolla, H.B.
Synthesis, biological screening and molecular docking studies of novel 4,6-pyrimidine derivatives as EGFR-TK inhibitors
(2016) Medicinal Chemistry Research, 25 (11), pp. 2534-2546. Cited 8 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981293966&doi=10.1007%2fs00044-016-1668-x&partnerID=40&md5=7c6325e1096f10ba49b6811396ae8dd4

DOI: 10.1007/s00044-016-1668-x
ISSN: 10542523
CODEN: MCREE

Mathew, B., Haridas, A., Uçar, G., Baysal, I., Adeniyi, A.A., Soliman, M.E.S., Joy, M., Mathew, G.E., Lakshmanan, B., Jayaprakash, V.
Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors
(2016) International Journal of Biological Macromolecules, 91, pp. 680-695. Cited 56 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84974851890&doi=10.1016%2fj.ijbiomac.2016.05.110&partnerID=40&md5=6638de2299a24ef1d7a875450c08b358

DOI: 10.1016/j.ijbiomac.2016.05.110
ISSN: 01418130
CODEN: IJBMD

Thakur, A., Dan, N., Bhakat, S., Jayaprakash, V., Banerjee, S.
5' adenosine monophosphate-activated protein kinase modulators as anticancer agents
(2016) Anti-Cancer Agents in Medicinal Chemistry, 16 (8), pp. 961-972. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981489379&doi=10.2174%2f1871520616666160211124240&partnerID=40&md5=db73c9a32d875d1dc7935c80ab96204f

DOI: 10.2174/1871520616666160211124240
ISSN: 18715206

Mathew, B., Haridas, A., Suresh, J., Mathew, G.E., Uçar, G., Jayaprakash, V.
Monoamine oxidase inhibitory action of chalcones: A Mini Review
(2016) Central Nervous System Agents in Medicinal Chemistry, 16 (2), pp. 120-136. Cited 48 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973649627&doi=10.2174%2f1871524915666151002124443&partnerID=40&md5=1d7201c08cdd39f0c2c8b2a8a2a25cc8

DOI: 10.2174/1871524915666151002124443
ISSN: 18715249

Mathew, B., Mathew, G.E., Uçar, G., Baysal, I., Suresh, J., Mathew, S., Haridas, A., Jayaprakash, V.
Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives
(2016) Chemistry and Biodiversity, pp. 1046-1052. Cited 32 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983032366&doi=10.1002%2fcbdv.201500367&partnerID=40&md5=483057f31e08503caf990904b105f9b5

DOI: 10.1002/cbdv.201500367
ISSN: 16121872
CODEN: CBHIA

Mathew, B., Mathew, G.E., Suresh, J., Ucar, G., Sasidharan, R., Anbazhagan, S., Vilapurathu, J.K., Jayaprakash, V.
Monoamine oxidase inhibitors: Perspective design for the treatment of depression and neurological disorders
(2016) Current Enzyme Inhibition, 12 (2), pp. 115-122. Cited 23 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981742462&doi=10.2174%2f1573408012666160402001715&partnerID=40&md5=024e9efd2f7156e1ff363c41ea89e73f

DOI: 10.2174/1573408012666160402001715
ISSN: 15734080

Timiri, A.K., Sinha, B.N., Jayaprakash, V.
Progress and prospects on DENV protease inhibitors
(2016) European Journal of Medicinal Chemistry, 117, pp. 125-143. Cited 25 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84963808195&doi=10.1016%2fj.ejmech.2016.04.008&partnerID=40&md5=31ad389e52b923dfd90c41b22655685f

DOI: 10.1016/j.ejmech.2016.04.008
ISSN: 02235234
CODEN: EJMCA

Badavath, V.N., Baysal, I., Ucar, G., Sinha, B.N., Jayaprakash, V.
Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis
(2016) ACS Medicinal Chemistry Letters, 7 (1), pp. 56-61. Cited 35 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955480132&doi=10.1021%2facsmedchemlett.5b00326&partnerID=40&md5=a5210867b5f00cca49abf19c1eaa8142

DOI: 10.1021/acsmedchemlett.5b00326
ISSN: 19485875
CODEN: AMCLC

Yasmin, S., Jayaprakash, V.
Design, in silico docking and predictive ADME properties of some thiazolidine-2, 4-diones derivatives as PPARγ modulators
(2016) International Journal of Pharmacy and Pharmaceutical Sciences, 8 (5), pp. 143-150. 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964854585&partnerID=40&md5=34d3bfacc358c082834bb37e6083b960

ISSN: 09751491

Badavath, V.N., Ucar, G., Sinha, B.N., Mondal, S.K., Jayaprakash, V.
Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis-II
(2016) ChemistrySelect, 1 (18), pp. 5879-5884. Cited 10 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85023183371&doi=10.1002%2fslct.201600914&partnerID=40&md5=78d9f555de409baaa328eee6c846acf7

DOI: 10.1002/slct.201600914
ISSN: 23656549

Subasri, S., Timiri, A.K., Barji, N.S., Jayaprakash, V., Vijayan, V., Velmurugan, D.
Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(3-nitrophenyl)acetamide monohydrate and N-(2-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide
(2016) Acta Crystallographica Section E: Crystallographic Communications, 72, pp. 1171-1175. Cited 3 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983002477&doi=10.1107%2fS2056989016011658&partnerID=40&md5=f8c3a2d4766e7649865956758e6fd715

DOI: 10.1107/S2056989016011658
ISSN: 20569890

Badavath, V.N., Baysal, I., Uçar, G., Mondal, S.K., Sinha, B.N., Jayaprakash, V.
Monoamine Oxidase Inhibitory Activity of Ferulic Acid Amides: Curcumin-Based Design and Synthesis
(2016) Archiv der Pharmazie, 349 (1), pp. 9-19. Cited 14 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955328643&doi=10.1002%2fardp.201500317&partnerID=40&md5=921a7c3699f1e9f009c3ad4f75c15177

DOI: 10.1002/ardp.201500317
ISSN: 03656233
CODEN: ARPMA

Mathew, B., Haridas, A., Uçar, G., Baysal, I., Joy, M., Mathew, G.E., Lakshmanan, B., Jayaprakash, V.
Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors
(2016) ChemMedChem, pp. 1161-1171. Cited 45 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973622864&doi=10.1002%2fcmdc.201600122&partnerID=40&md5=909dfae534294988f971c68077143be0

DOI: 10.1002/cmdc.201600122
ISSN: 18607179
CODEN: CHEMG

Mohd Siddique, M.U., McCann, G.J.P., Sonawane, V., Horley, N., Williams, I.S., Joshi, P., Bharate, S.B., Jayaprakash, V., Sinha, B.N., Chaudhuri, B.
Biphenyl urea derivatives as selective CYP1B1 inhibitors
(2016) Organic and Biomolecular Chemistry, 14 (38), pp. 8931-8936. Cited 16 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84989162902&doi=10.1039%2fc6ob01506a&partnerID=40&md5=e002e72762872d691d8628ebd8f4836f

DOI: 10.1039/c6ob01506a
ISSN: 14770520
CODEN: OBCRA

Hatti, I., Sreenivasulu, R., Jadav, S.S., Jayaprakash, V., Kumar, C.G., Raju, R.R.
Synthesis, cytotoxic activity and docking studies of new 4-aza-podophyllotoxin derivatives
(2015) Medicinal Chemistry Research, 24 (8), pp. 3305-3313. Cited 49 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937813494&doi=10.1007%2fs00044-015-1375-z&partnerID=40&md5=36cf8b608d04f7cfff69cc1dd5049cd4

DOI: 10.1007/s00044-015-1375-z
ISSN: 10542523
CODEN: MCREE

Timiri, A.K., Subasri, S., Kesherwani, M., Vishwanathan, V., Sinha, B.N., Velmurugan, D., Jayaprakash, V.
Synthesis and molecular modelling studies of novel sulphonamide derivatives as dengue virus 2 protease inhibitors
(2015) Bioorganic Chemistry, 62, art. no. 1832, pp. 74-82. Cited 19 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84938489701&doi=10.1016%2fj.bioorg.2015.07.005&partnerID=40&md5=ddd0fc413e40dd8f3624a60b5a7d5b98

DOI: 10.1016/j.bioorg.2015.07.005
ISSN: 00452068
CODEN: BOCMB

Jadav, S.S., Kaptein, S., Timiri, A., De Burghgraeve, T., Badavath, V.N., Ganesan, R., Sinha, B.N., Neyts, J., Leyssen, P., Jayaprakash, V.
Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus e protein inhibitors
(2015) Bioorganic and Medicinal Chemistry Letters, 25 (8), pp. 1747-1752. Cited 26 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84940003248&doi=10.1016%2fj.bmcl.2015.02.059&partnerID=40&md5=21b420ee4b17e248144171c2a24e0ee2

DOI: 10.1016/j.bmcl.2015.02.059
ISSN: 0960894X
CODEN: BMCLE

Jadav, S.S., Sinha, B.N., Hilgenfeld, R., Pastorino, B., De Lamballerie, X., Jayaprakash, V.
Thiazolidone derivatives as inhibitors of chikungunya virus
(2015) European Journal of Medicinal Chemistry, 89, pp. 172-178. Cited 34 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908447953&doi=10.1016%2fj.ejmech.2014.10.042&partnerID=40&md5=d08cb96cf588abb87370e68ac7d1c2c2

DOI: 10.1016/j.ejmech.2014.10.042
ISSN: 02235234
CODEN: EJMCA

Badavath, V.N., Sinha, B.N., Jayaprakash, V.
Design, in-silico docking and predictive adme properties of novel pyrazoline derivatives with selective human MAO inhibitory activity
(2015) International Journal of Pharmacy and Pharmaceutical Sciences, 7 (12), pp. 277-282. Cited 5 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949754723&partnerID=40&md5=ee4f51d0ec247eefe88177a789c71d75

ISSN: 09751491

Jadav, S.S., Kumar, A., Ahsan, M.J., Jayaprakash, V.
Ebola virus: Current and future perspectives
(2015) Infectious Disorders - Drug Targets, 15 (1), pp. 20-31. Cited 9 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930890909&doi=10.2174%2f1871526515666150320162259&partnerID=40&md5=72c3f76329c049bd0f9d9484d259fbdb

DOI: 10.2174/1871526515666150320162259
ISSN: 18715265

Alavala, R.R., Kulandaivelu, U., Bonagiri, P., Boyapati, S., Jayaprakash, V., Subramaniam, A.T.
Synthesis and antiviral activity of dihydropyrimidines – ciprofloxacin mannich bases against various viral strains
(2015) Anti-Infective Agents, 13 (2), pp. 154-165. Cited 2 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960959402&doi=10.2174%2f221135251302151029111113&partnerID=40&md5=93eab7a54794aec17397372549b090ba

DOI: 10.2174/221135251302151029111113
ISSN: 22113525

Bhakat, S., Delang, L., Kaptein, S., Neyts, J., Leyssen, P., Jayaprakash, V.
Reaching beyond HIV/HCV: Nelfinavir as a potential starting point for broad-spectrum protease inhibitors against dengue and chikungunya virus
(2015) RSC Advances, 5 (104), pp. 85938-85949. Cited 10 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944754654&doi=10.1039%2fc5ra14469h&partnerID=40&md5=55dd0787ce16341332e22eacaae94c16

DOI: 10.1039/c5ra14469h
ISSN: 20462069
CODEN: RSCAC

Jadav, S.S., Sinha, B.N., Pastorino, B., De Lamballerie, X., Hilgenfeld, R., Jayaprakash, V.
Identification of pyrazole derivative as an antiviral agent against chikungunya through HTVS
(2015) Letters in Drug Design and Discovery, 12 (4), pp. 292-301. Cited 13 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84926452429&doi=10.2174%2f1570180811666141001005402&partnerID=40&md5=a3145287a7a264ce36ba18087b880db5

DOI: 10.2174/1570180811666141001005402
ISSN: 15701808
CODEN: LDDDA

Nayak, B.V., Ciftci-Yabanoglu, S., Bhakat, S., Timiri, A.K., Sinha, B.N., Ucar, G., Soliman, M.E.S., Jayaprakash, V.
Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones
(2015) Bioorganic Chemistry, 58, pp. 72-80. Cited 30 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919725488&doi=10.1016%2fj.bioorg.2014.11.008&partnerID=40&md5=2d5b0aa8c3a5a1706e7eb272304d8256

DOI: 10.1016/j.bioorg.2014.11.008
ISSN: 00452068
CODEN: BOCMB

Bhakat, S., Karubiu, W., Jayaprakash, V., Soliman, M.E.S.
A perspective on targeting non-structural proteins to combat neglected tropical diseases: Dengue, West Nile and Chikungunya viruses
(2014) European Journal of Medicinal Chemistry, 87, pp. 677-702. Cited 29 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908030336&doi=10.1016%2fj.ejmech.2014.10.010&partnerID=40&md5=97cd4a41ea96e045e9282fa738d3a655

DOI: 10.1016/j.ejmech.2014.10.010
ISSN: 02235234
CODEN: EJMCA

Rathinavelusamy, P., Mazumder, P.M., Sasmal, D., Jayaprakash, V.
Evaluation of in silico, in vitro α-amylase inhibition potential and antidiabetic activity of Pterospermum acerifolium bark
(2014) Pharmaceutical Biology, 52 (2), pp. 199-207. Cited 5 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891786739&doi=10.3109%2f13880209.2013.823551&partnerID=40&md5=b666448d88e80eb7f0da886a06ad599d

DOI: 10.3109/13880209.2013.823551
ISSN: 13880209
CODEN: PHBIF

Bojanapu, A., Subramaniam, A.T., Munusamy, J., Dhanapal, K., Chennakesavalu, J., Sellappan, M., Jayaprakash, V.
Validation and method development of tadalafil in bulk and tablet dosage form by RP-HPLC
(2014) Drug Research, 65 (2), pp. 82-85. Cited 4 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923567123&doi=10.1055%2fs-0034-1372608&partnerID=40&md5=be8b8fbad6b611fb466177b362ec8458

DOI: 10.1055/s-0034-1372608
ISSN: 21949379
CODEN: DRSGA

Paramaguru, R., Mazumder, P.M., Sasmal, D., Jayaprakash, V.
Antidiabetic activity of pterospermum acerifolium flowers and glucose uptake potential of bioactive fraction in l6 muscle cell lines with its HPLC fingerprint
(2014) BioMed Research International, 2014, art. no. 459376, . Cited 6 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84911191808&doi=10.1155%2f2014%2f459376&partnerID=40&md5=5c3c8d65034e8f5d01ca2d797c58e6b1

DOI: 10.1155/2014/459376
ISSN: 23146133

Subasri, S., Kumar, T.A., Sinha, B.N., Jayaprakash, V., Velmurugan, D.
2-[(4,6-Diaminopyrimidin-2-yl)sulfanyl]-N-(2-methylphenyl)acetamide
(2014) Acta Crystallographica Section E: Structure Reports Online, 70 (8), pp. o850. Cited 5 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905482191&doi=10.1107%2fS1600536814015256&partnerID=40&md5=e29c17ff1b6753cc53961ded4ff38606

DOI: 10.1107/S1600536814015256
ISSN: 16005368

Kulandaivelu, U., Chilakamari, L.M., Jadav, S.S., Rao, T.R., Jayaveera, K.N., Shireesha, B., Hauser, A.-T., Senger, J., Marek, M., Romier, C., Jung, M., Jayaprakash, V.
Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8
(2014) Bioorganic Chemistry, 57, pp. 116-120. Cited 6 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907930844&doi=10.1016%2fj.bioorg.2014.08.005&partnerID=40&md5=addc698a913a5703be843f09c776e7ba

DOI: 10.1016/j.bioorg.2014.08.005
ISSN: 00452068
CODEN: BOCMB

Vishnu Nayak, B., Ciftci-Yabanoglu, S., Jadav, S.S., Jagrat, M., Sinha, B.N., Ucar, G., Jayaprakash, V.
Monoamine oxidase inhibitory activity of 3,5-biaryl-4,5-dihydro-1H- pyrazole-1-carboxylate derivatives
(2013) European Journal of Medicinal Chemistry, 69, pp. 762-767. Cited 43 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884919003&doi=10.1016%2fj.ejmech.2013.09.010&partnerID=40&md5=1acaed512fe8635e1929968ee79f56bc

DOI: 10.1016/j.ejmech.2013.09.010
ISSN: 02235234
CODEN: EJMCA

Mahapatra, M., Kulandaivelu, U., Saiko, P., Graser, G., Szekeres, T., Andrei, G., Snoeck, R., Balzarini, J., Jayaprakash, V.
Methyl-2-arylidene hydrazinecarbodithioates: Synthesis and biological activity
(2013) Chemical Papers, 67 (6), pp. 650-656. Cited 6 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879690639&doi=10.2478%2fs11696-013-0346-4&partnerID=40&md5=e502c3e2dc145df4115dda13c6e2cc17

DOI: 10.2478/s11696-013-0346-4
ISSN: 03666352
CODEN: CHPAE

Kulandaivelu, U., Shireesha, B., Mahesh, C., Vidyasagar, J.V., Rao, T.R., Jayaveera, K.N., Saiko, P., Graser, G., Szekeres, T., Jayaprakash, V.
Synthesis antimicrobial and anticancer activity of N′- arylmethylidene-piperazine-1-carbothiohydrazide
(2013) Medicinal Chemistry Research, 22 (6), pp. 2802-2808. Cited 8 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879688615&doi=10.1007%2fs00044-012-0279-4&partnerID=40&md5=b9e13aad327c498cb3b50d0181fd9633

DOI: 10.1007/s00044-012-0279-4
ISSN: 10542523
CODEN: MCREE

Ferreras, J.A., Gupta, A., Amin, N.D., Basu, A., Sinha, B.N., Worgall, S., Jayaprakash, V., Quadri, L.E.N.
Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis
(2011) Bioorganic and Medicinal Chemistry Letters, 21 (21), pp. 6533-6537. Cited 9 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054786404&doi=10.1016%2fj.bmcl.2011.08.052&partnerID=40&md5=767c5af2e4e19c6b0f2396b5969f09c4

DOI: 10.1016/j.bmcl.2011.08.052
ISSN: 0960894X
CODEN: BMCLE

Jagrat, M., Behera, J., Yabanoglu, S., Ercan, A., Ucar, G., Sinha, B.N., Sankaran, V., Basu, A., Jayaprakash, V.
Pyrazoline based MAO inhibitors: Synthesis, biological evaluation and SAR studies
(2011) Bioorganic and Medicinal Chemistry Letters, 21 (14), pp. 4296-4300. Cited 41 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959891957&doi=10.1016%2fj.bmcl.2011.05.057&partnerID=40&md5=5a3d68f80688cdf129775ee7895a6b7b

DOI: 10.1016/j.bmcl.2011.05.057
ISSN: 0960894X
CODEN: BMCLE

Kulandaivelu, U., Padmini, V.G., Suneetha, K., Shireesha, B., Vidyasagar, J.V., Rao, T.R., Jayaveera, K.N., Basu, A., Jayaprakash, V.
Synthesis, antimicrobial and anticancer activity of new thiosemicarbazone derivatives
(2011) Archiv der Pharmazie, 344 (2), pp. 84-90. Cited 29 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79551696597&doi=10.1002%2fardp.201000201&partnerID=40&md5=9624489b34c5407af3ecc226fe9376b3

DOI: 10.1002/ardp.201000201
ISSN: 03656233
CODEN: ARPMA

Saiko, P., Graser, G., Giessrigl, B., Lackner, A., Grusch, M., Krupitza, G., Basu, A., Sinha, B.N., Jayaprakash, V., Jaeger, W., Fritzer-Szekeres, M., Szekeres, T.
A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C)
(2011) Biochemical Pharmacology, 81 (1), pp. 50-59. Cited 11 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-78549281372&doi=10.1016%2fj.bcp.2010.09.006&partnerID=40&md5=374e13a8f66e471c7c310764436028f4

DOI: 10.1016/j.bcp.2010.09.006
ISSN: 00062952
CODEN: BCPCA

Jayaprakash, V., Yabanoglu, S., Sinha, B.N., Ucar, G.
Pyrazoline-based mycobactin analogues as dual inhibitors of MAO/cholinesterase [MAO ve kolinesteraz dual i?nhibitörü pirazolin-bazli mikobaktin analoglari]]
(2010) Turkish Journal of Biochemistry, 35 (2), pp. 91-98. Cited 15 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954755639&partnerID=40&md5=2bc3178d3678011bdc01242d93556af2

ISSN: 1303829X

Chetan, B., Bunha, M., Jagrat, M., Sinha, B.N., Saiko, P., Graser, G., Szekeres, T., Raman, G., Rajendran, P., Moorthy, D., Basu, A., Jayaprakash, V.
Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity
(2010) Bioorganic and Medicinal Chemistry Letters, 20 (13), pp. 3906-3910. Cited 51 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954315435&doi=10.1016%2fj.bmcl.2010.05.020&partnerID=40&md5=4a4b4a85395b8eea308dc518d1d7afc1

DOI: 10.1016/j.bmcl.2010.05.020
ISSN: 0960894X
CODEN: BMCLE

Mishra, N., Oraon, A., Dev, A., Jayaprakash, V., Basu, A., Pattnaik, A.K., Tripapthi, S.N., Akhtar, M., Ahmad, S., Swaroop, S., Basu, M.
Anticonvulsant activity of Benkara malabarica (Linn.) root extract: In vitro and in vivo investigation
(2010) Journal of Ethnopharmacology, 128 (2), pp. 533-536. Cited 15 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77649342571&doi=10.1016%2fj.jep.2010.01.042&partnerID=40&md5=e142e73960c84d7e718d8b639c051da8

DOI: 10.1016/j.jep.2010.01.042
ISSN: 03788741
CODEN: JOETD

Chakrabarty, S., Jasmine, Bhadaliya, C., Sinha, B.N., Mahesh, A., Bai, H., Blond, S.Y., Jayaprakash, V.
Inhibitors of human histone deacetylase: Synthesis and enzyme assay of hydroxamates with piperazine linker
(2010) Archiv der Pharmazie, 343 (3), pp. 167-172. Cited 5 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77949376273&doi=10.1002%2fardp.200900117&partnerID=40&md5=673a49362823d4348c5924aab33a7323

DOI: 10.1002/ardp.200900117
ISSN: 03656233
CODEN: ARPMA

Karuppasamy, M., Mahapatra, M., Yabanoglu, S., Ucar, G., Sinha, B.N., Basu, A., Mishra, N., Sharon, A., Kulandaivelu, U., Jayaprakash, V.
Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies
(2010) Bioorganic and Medicinal Chemistry, 18 (5), pp. 1875-1881. Cited 42 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77349110399&doi=10.1016%2fj.bmc.2010.01.043&partnerID=40&md5=0653a9f13c6411b63ac4265a63a12704

DOI: 10.1016/j.bmc.2010.01.043
ISSN: 09680896
CODEN: BMECE

Sahoo, A., Yabanoglu, S., Sinha, B.N., Ucar, G., Basu, A., Jayaprakash, V.
Towards development of selective and reversible pyrazoline based MAO-inhibitors: Synthesis, biological evaluation and docking studies
(2010) Bioorganic and Medicinal Chemistry Letters, 20 (1), pp. 132-136. Cited 59 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-72149094342&doi=10.1016%2fj.bmcl.2009.11.015&partnerID=40&md5=93817683a5dc694fd3b5196c396c2fa3

DOI: 10.1016/j.bmcl.2009.11.015
ISSN: 0960894X
CODEN: BMCLE

Mishra, N., Basu, A., Jayaprakash, V., Sharon, A., Basu, M., Patnaik, K.K.
Structure based virtual screening of GSK-3β: Importance of protein flexibility and induced fit
(2009) Bioorganic and Medicinal Chemistry Letters, 19 (19), pp. 5582-5585. Cited 7 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-70049111237&doi=10.1016%2fj.bmcl.2009.08.042&partnerID=40&md5=1c2264150497634fac066ad40a6848bc

DOI: 10.1016/j.bmcl.2009.08.042
ISSN: 0960894X
CODEN: BMCLE

Basu, A., Jasu, K., Jayaprakash, V., Mishra, N., Ojha, P., Bhattacharya, S.
Development of CoMFA and CoMSIA models of cytotoxicity data of anti-HIV-1-phenylamino-1H-imidazole derivatives
(2009) European Journal of Medicinal Chemistry, 44 (6), pp. 2400-2407. Cited 36 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-64249142581&doi=10.1016%2fj.ejmech.2008.09.043&partnerID=40&md5=53ab804277bababe033bdf36fc25127c

DOI: 10.1016/j.ejmech.2008.09.043
ISSN: 02235234
CODEN: EJMCA

Jayaprakash, V., Sinha, B.N., Ucar, G., Ercan, A.
Pyrazoline-based mycobactin analogues as MAO-inhibitors
(2008) Bioorganic and Medicinal Chemistry Letters, 18 (24), pp. 6362-6368. Cited 54 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-56249144473&doi=10.1016%2fj.bmcl.2008.10.084&partnerID=40&md5=0e39c962a4a7107a28ed6830560ee654

DOI: 10.1016/j.bmcl.2008.10.084
ISSN: 0960894X
CODEN: BMCLE

Dewangan, P., Verma, S.M., Basu, A., Venkatesan, J.
Multidimensional consensus QSAR: A step towards integrating CoMFA, CoMSIA with traditional QSAR methodologies
(2008) Letters in Drug Design and Discovery, 5 (8), pp. 494-502. Cited 1 time.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-58049199411&doi=10.2174%2f157018008786898563&partnerID=40&md5=f61881f2ea2035e9ba2a424ae817c0cd

DOI: 10.2174/157018008786898563
ISSN: 15701808

Krishnan, K., Prathiba, K., Jayaprakash, V., Basu, A., Mishra, N., Zhou, B., Hu, S., Yen, Y.
Synthesis and Ribonucleotide reductase inhibitory activity of thiosemicarbazones
(2008) Bioorganic and Medicinal Chemistry Letters, 18 (23), pp. 6248-6250. Cited 31 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-55549087863&doi=10.1016%2fj.bmcl.2008.09.097&partnerID=40&md5=9d80bde005cd5d89f30407de2dc2f604

DOI: 10.1016/j.bmcl.2008.09.097
ISSN: 0960894X
CODEN: BMCLE

Stirrett, K.L., Ferreras, J.A., Jayaprakash, V., Sinha, B.N., Ren, T., Quadri, L.E.N.
Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis
(2008) Bioorganic and Medicinal Chemistry Letters, 18 (8), pp. 2662-2668. Cited 50 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-41849151739&doi=10.1016%2fj.bmcl.2008.03.025&partnerID=40&md5=f3a649388a47041a219bfae8a5e94f44

DOI: 10.1016/j.bmcl.2008.03.025
ISSN: 0960894X
CODEN: BMCLE

Venkatesan, J., Pandeya, S., Selvakumar, D.
Synthesis and biological evaluation of 4,6-diaryl substituted-4,5-dihydro- 2-amino pyrimidines
(2007) Indian Journal of Pharmaceutical Sciences, 69 (4), pp. 586-589. Cited 7 times.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-36048969267&doi=10.4103%2f0250-474x.36954&partnerID=40&md5=bfb992c3dddd43e502d887363a86392c

DOI: 10.4103/0250-474x.36954
ISSN: 0250474X
CODEN: IJSID

Venkatesan, J., Pandeya, S.N., Selvakumar, D., Babuthandapani, A.
Synthesis and biological evaluation of 4,6-diaryl substituted- 4,5-dihydro pyrimidinyl-2-ureas
(2005) Indian Drugs, 42 (7), pp. 447-452. 
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955458150&partnerID=40&md5=2ba54ac207a617a92407adfd48b4f6bf

ISSN: 0019462X
CODEN: INDRB

 

 

 

  Member of Professional Bodies
 

 

  • Registered Pharmacist (17905 A2), Tamilnadu Pharmacy Council, Vadapalani, Chennai-600026 (TN), India
  • APTI Life Member (TN/LM-187), H.Q: No.620 D, 35th Cross, 2nd Block, Rajajinagar, Bengaluru-560 010 (KA), India
  Current Sponsored Projects
 

Co-Principal Investigator

Title: Aptamer-based Diagnostic Kit for Detection of Corona Virus Infection (CoVapt)

Scheme & Agency: Science & Engineering Research Board, DST,  Govt. of India, India

File No.: CVD/2020/000311 dt. 17th July 2020

Amount Sanctioned: 15,74,672/-

Duration: One year (2020-2021)

Principal Investigator

Scheme & Agency: Newton Bhabha PhD Placement Programme (2019-2020), Department of Biotechnlogy (DBT), Govt of India, India

File No.: BT/IN/NBPP/20/2019-20 dt. 4th March 2020

Amount Sanctioned: 17,38,235/-

Duration: Four Months (2020-2021)

Principal Investigator

Title: Design & Development of Inhibitors of DENV Methyltransferase for the Treatment of Dengue Viral Infection

Scheme & Agency: Research Promotion Scheme (RPS), All India Council for Technical Education (AICTE), Govt of India, India

File No.: 8-70/RIFD/RPS/POICY-1/2016-17 dt. 4th August 2017

Amount Sanctioned: 17,38,235/-

Duration: Three years (2017-2020)

Co-Principal Investigator

Title: Design and Synthesis of Substrate Based Peptide Inhibitors of DENV Protease for the Treatment of Dengue Viral Infections

Principal Investigator: Dr. Barij Nayan Sinha & Co-Principal Investigator: Dr. B. Sarkar

Scheme & Agency: EMR (Individual Centric), Science & Engineering Research Board, DST,  Govt. of India, India

File No.: EMR/2016/005711

Amount Sanctioned: 45,60,400/-

Duration: Three years (2017-2020)

Principal Investigator

Title: Phenyloxazoline Synthetase Inhibitors as Antitubercular Agents (POSIAA)

Co-Principal Investigator: Dr. Abhimanyu Dev

Scheme & Agency: EMR (Individual Centric), Science & Engineering Research Board, DST,  Govt. of India, India

File No.: EMR/2016/000675

Amount Sanctioned: 53,73,450/-

Duration: Three years (2016-2019)

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Design & Synthesis of potent dual inhibitors of Cdk-4 and tubulin as anticancer agents

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: An Indo-UK Project sponsored by University Grants Commission (UGC), Govt. of India, India

Amount Sanctioned: 30,88,800/-

Duration: Two years (2013-2015)

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Structure-based discovery of antivirals for the treatment of Chikungunya virus infections (Anti-Chick)

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: New-Indigo Eranet, An Indo-German Project sponsored by Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India

Amount Sanctioned: 34,62,000/-

Duration: (Two Years) 2011-2013

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Structure-based design of Dengue virus protease inhibitors

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: An Indo-German Project sponsored by Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India

Amount Sanctioned: 24,51,800/-

Duration: (3 Years) 2011-2014

Co-principle Investigator

Title: Grid-based Virtual Screening for TB (Grid-ViSiT)

Principle Investigator: K. K. Patnaik, Dept. of Comp. Sci. Engg., BIT, Mesra

Scheme & Agency: Research Promotion Scheme (RPS) sponsored by All IndiaCouncil for Technical Education (AICTE), Govt. of India, India

Amount Sanctioned: Rs. 6,50,000/-

Duration: (Two Years) 2008-2010

  Text and Reference Books
 

Book

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents, Edited by Venkatesan Jayaprakash, Daniele Castagnolo, Yusuf Ozkat, CRC Press, 2019 (ISBN: 978-1138541245)

Venkatesan Jayaprakash, Barij Nayan Sinha, Anti-tubercular Drug Design Exploring Mycobactin Biosynthetic Pathway, Designing molecules that mimics hydroxyphenyl oxazoline portion of mycobactin, LAP Lambert Academic Publication, Germany, 2013 (ISBN:978-3-659-43995-7)

Book Chapter

Venkatesan Jayaprakash, Ajay Kumar Timiri, Barij Nayan Sinha, "Studies on Inhibitors of Dengue Virus Protease", Advances in Studies on Enzyme Inhibitors As Drugs: Anticancer and Antiviral Drugs, Vol. I, Editor, S. P. Gupta, Nova Science Publisher Inc., New York, 2017(ISBN:978-1-53610-504-9)

  Patent
 
  • Application No. 325/KOL/2014 A; Title: 2-(4,6-diaminopyrimidin-2-ylthio)-N-aryl acetamide derivatives, their synthesis, antiviral activity and methods thereof
  • Application No. 191/KOL/2014 A; Title: 4-(1,3-dioxoisoindolin-2-yl)-benzenesulfonamide derivatives, their synthesis, antiviral activity and methods thereof
  • Application No. 811/KOL/2013; Title: Arylmethylidene heterocyclics as novel antiviral agents against chikungunya viral infection
  • Application No. 349/CHE/2011; Title: Dihydropyrimidine Derivatives as pharmacologically active agents
  Member, Editorial Board
 

Editor: Journal of Pharmaceutical Chemistry (ISSN: 2349-5731)

Editorial Board Member: PHARMBIT (ISSN: 0973-6204)