Birla Institute of Technology, Mesra
   
DR. VENKATESAN JAYAPRAKASH
Associate Professor , Pharmaceutical Sciences and Tech
M. Pharm., Ph.D.
Contact Address
Residence Address 26/46, Ragavendra Street, Komarapalayam, Namakkal-638183 (TN) India
Permanent Address DI/29, Inner Campus, Birla Institute of Technology, Mesra, Ranchi-835215 (JH) India
Phone (Office) 2275290
Phone Residence 0651-2275555
Email Id venkatesanj@bitmesra.ac.in
   Joined Institute on : 15-Feb-2004

  Work Experience
 
Teaching : 15 Years

Research : 15 Years


  Professional Background
 
  • Associate Professor (Since July 2016), Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India
  • Assistant Professor (Jun 2007 to June 2016), Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India 
  • Lecturer (Feb 2004 to May 2007), Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215 (JH), India 
  • Assisstant Professor (Jul 2002 to Jan 2004), Sanjivani College of Pharmaceutical Sciences, Ketri-333503 (RJ), India 
  • Assistant Professor (Apr 1999 to Jun 2002), JKKMMRF College of Pharmacy, Komarapalayam-638183 (TN), India
  • Tutor (Nov 1996 to Aug 1997), JKKMMRF College of Pharmacy, Komarapalayam-638183 (TN), India

  Research Areas
 
Expertise
  • Organic Synthesis and Medicinal Chemistry
  • Molecular Modeling and Drug Design

Research Area:

  • Antitubercular: Mycobactin bioynthesis inhibitors
  • CNS: Monoamine oxidase inhibitors
  • Anticancer: HDAC inhibitors, RR inhibitors, CDK inhibitors & CYP inhibitors
  • Antivirals: Protease inhibitors (DenV & ChikV) , Fusion inhibitors (DenV)  


   Publications
 

Scopus (Updated on 25 Jan 2019)

Scopus Author ID: 23995556000

ORCID ID: http://orcid.org/0000-0002-9724-4153

 

Total Citations: 766

Author h-index: 17 

 

Sonawane, V., Mohd Siddique, M. U., Gatchie, L., Williams, I. S., Bharate, S. B., Jayaprakash, V., Sinha, B. N., Chaudhuri, B.

CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficeintly reverse B[a]P toxicity and cisplatin resistance

(2019) European Journal of Pharmaceutical Sciences, 131, 177-194.

 

DOI: https://doi.org/10.1016/j.ejps.2019.02.016

Share Link: https://authors.elsevier.com/c/1YdPi3J1dIUlnP

 

Sonawane, V., Mohd Siddique, M.U., Jadav, S.S., Sinha, B.N., Jayaprakash, V., Chaudhuri, B.

Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy

(2019) European Journal of Medicinal Chemistry, 165, pp. 115-132. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060116430&doi=10.1016%2fj.ejmech.2019.01.011&partnerID=40&md5=d486c0671004870f13cad8d25305e663

 

DOI: 10.1016/j.ejmech.2019.01.011           

Share Link: https://authors.elsevier.com/a/1YQ3BoqiQ0Q5A

 

Mohd Siddique, M.U., Barbhuiya, T.K., Sinha, B.N., Jayaprakash, V.

Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1

(2019) European Journal of Medicinal Chemistry, pp. 28-36. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057327708&doi=10.1016%2fj.ejmech.2018.11.039&partnerID=40&md5=7af5488ab12303e79ed6f0306dab0019

 

DOI: 10.1016/j.ejmech.2018.11.039.          

Share Link: https://authors.elsevier.com/a/1Y8gB_55HFPGrM

 

Molla, A., Ranjan, S., Rao, M.S., Dar, A.H., Shyam, M., Jayaprakash, V., Hussain, S.

Borax Catalysed Domino Synthesis of Highly Functionalised Spirooxindole and Chromenopyridine Derivatives: X-Ray Structure, Hirshfeld Surface Analysis and Molecular Docking Studies

(2018) ChemistrySelect, 3 (30), pp. 8669-8677. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051709266&doi=10.1002%2fslct.201801867&partnerID=40&md5=66a48c787691c4a4e74459514b70bb7c

 

DOI: 10.1002/slct.201801867

 

Bagchi, S., Rathee, P., Jayaprakash, V., Banerjee, S.

Farnesyl transferase inhibitors as potential anticancer agents

(2018) Mini-Reviews in Medicinal Chemistry, 18 (19), pp. 1611-1623. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055202698&doi=10.2174%2f1389557518666180801110342&partnerID=40&md5=9cfe378cb13d6ff0d15399172d9a9831

 

DOI: 10.2174/1389557518666180801110342

 

Siddique, M.U.M., Sinha, B.N., Jayaprakash, V.

Comparative shape and electrostatic study of highly potent and selective CYP1B1 inhibitor: Assessment of active site of CYP1B1 by binding mode analysis using site map tool

(2018) Indian Journal of Pharmaceutical Education and Research, 52 (1), pp. 159-165. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047495474&doi=10.5530%2fijper.52.1.18&partnerID=40&md5=21eb753da35986193a644b19a753ab91

 

DOI: 10.5530/ijper.52.1.18

 

Choudhury, M., Viswanathan, V., Timiri, A.K., Sinha, B.N., Jayaprakash, V., Velmurugan, D.

Crystal structures and Hirshfeld surface analyses of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]- N -(pyridin-2-yl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]- N -(pyrazin-2-yl)acetamide

(2018) Acta Crystallographica Section E: Crystallographic Communications, 74, pp. 718-723. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046728109&doi=10.1107%2fS2056989018005704&partnerID=40&md5=19afe7a1e0d9bb88de5cdacfbb35af50

 

DOI: 10.1107/S2056989018005704

 

Nath, C., Badavath, V.N., Thakur, A., Ucar, G., Acevedo, O., Mohd Siddique, M.U., Jayaprakash, V.

Curcumin-based pyrazoline analogues as selective inhibitors of human monoamine oxidase A

(2018) MedChemComm, 9 (7), pp. 1164-1171. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050517566&doi=10.1039%2fc8md00196k&partnerID=40&md5=825007b32887e2e6c43a04947101fede

 

DOI: 10.1039/c8md00196k

 

Jadav, S.S., Sinha, B.N., Hilgenfeld, R., Jayaprakash, V.

Computer-aided structure based drug design approaches for the discovery of new anti-CHIKV agents

(2017) Current Computer-Aided Drug Design, 13 (4), pp. 346-361. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038628214&doi=10.2174%2f1573409913666170309145308&partnerID=40&md5=a8b830e588d0f1f4af66248e3215427e

 

DOI: 10.2174/1573409913666170309145308

 

Yasmin, S., Capone, F., Laghezza, A., Piaz, F.D., Loiodice, F., Vijayan, V., Devadasan, V., Mondal, S.K., Atll, Ö., Baysal, M., Pattnaik, A.K., Jayaprakash, V., Lavecchia, A.

Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes

(2017) Scientific Reports, 7 (1), art. no. 14453, . Cited 1 time.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032638225&doi=10.1038%2fs41598-017-14776-0&partnerID=40&md5=80e1ca6c281f0e4237c1f9a9ef49ae54

 

DOI: 10.1038/s41598-017-14776-0

 

Graser-Loescher, G., Schoenhuber, A., Ciglenec, C., Eberl, S., Krupitza, G., Mader, R.M., Jadav, S.S., Jayaprakash, V., Fritzer-Szekeres, M., Szekeres, T., Saiko, P.

Thiosemicarbazone derivatives, thiazolyl hydrazones, effectively inhibit leukemic tumor cell growth: Down-regulation of ribonucleotide reductase activity and synergism with arabinofuranosylcytosine

(2017) Food and Chemical Toxicology, 108, pp. 53-62. Cited 2 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85025589698&doi=10.1016%2fj.fct.2017.07.029&partnerID=40&md5=cc71849765b2fc34d2678a5f96a62d6e

 

DOI: 10.1016/j.fct.2017.07.029

 

Yasmin, S., Jayaprakash, V.

Thiazolidinediones and PPAR orchestra as antidiabetic agents: From past to present

(2017) European Journal of Medicinal Chemistry, 126, pp. 879-893. Cited 16 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006054934&doi=10.1016%2fj.ejmech.2016.12.020&partnerID=40&md5=48c94c2d22d56fc4fa4920d6577ade45

 

DOI: 10.1016/j.ejmech.2016.12.020

 

Subasri, S., Kumar, T.A., Sinha, B.N., Jayaprakash, V., Viswanathan, V., Velmurugan, D.

Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(naphthalen-1-yl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide

(2017) Acta Crystallographica Section E: Crystallographic Communications, 73, pp. 306-309. Cited 1 time.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011593492&doi=10.1107%2fS2056989017001293&partnerID=40&md5=2da48eb87f3f3aa2f86ac5659b6a8c5a

 

DOI: 10.1107/S2056989017001293

 

Choudhury, M., Viswanathan, V., Timiri, A.K., Sinha, B.N., Jayaprakash, V., Velmurugan, D.

Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(2,4-dimethylphenyl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(3-methoxyphenyl)acetamide Choudhury Manisha

(2017) Acta Crystallographica Section E: Crystallographic Communications, 73, pp. 996-1000. Cited 2 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85023192428&doi=10.1107%2fS2056989017008143&partnerID=40&md5=1ebde24eeb62f45b30771e787c73911f

 

DOI: 10.1107/S2056989017008143

 

Badavath, V.N., Nath, C., Ganta, N.M., Ucar, G., Sinha, B.N., Jayaprakash, V.

Design, synthesis and MAO inhibitory activity of 2-(arylmethylidene)-2,3-dihydro-1-benzofuran-3-one derivatives

(2017) Chinese Chemical Letters, 28 (7), pp. 1528-1532. Cited 4 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017447980&doi=10.1016%2fj.cclet.2017.02.009&partnerID=40&md5=e7697d27d879104c651603d8c19976c6

 

DOI: 10.1016/j.cclet.2017.02.009

 

Subasri, S., Kumar, T.A., Sinha, B.N., Jayaprakash, V., Viswanathan, V., Velmurugan, D.

Crystal structures of N-(4-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide and N-(3-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide

(2017) Acta Crystallographica Section E: Crystallographic Communications, 73, pp. 467-471. Cited 1 time.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017322361&doi=10.1107%2fS2056989017003243&partnerID=40&md5=7ce94a54e5606bed3fd923ea8586252a

 

DOI: 10.1107/S2056989017003243

 

Mohd Siddique, M.U., McCann, G.J.P., Sonawane, V.R., Horley, N., Gatchie, L., Joshi, P., Bharate, S.B., Jayaprakash, V., Sinha, B.N., Chaudhuri, B.

Quinazoline derivatives as selective CYP1B1 inhibitors

(2017) European Journal of Medicinal Chemistry, 130, pp. 320-327. Cited 15 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014286174&doi=10.1016%2fj.ejmech.2017.02.032&partnerID=40&md5=c841e3f8f5ebf7f1418d411b590e3fe5

 

DOI: 10.1016/j.ejmech.2017.02.032

 

Kasthuri, J.K., Singh Jadav, S., Thripuram, V.D., Gundabolu, U.R., Ala, V.B., Kolla, J.N., Jayaprakash, V., Ahsan, M.J., Bollikolla, H.B.

Synthesis, Characterization, Docking and Study of Inhibitory Action of Some Novel C-Alkylated Chalcones on 5-LOX Enzyme

(2017) ChemistrySelect, 2 (28), pp. 8771-8778. Cited 2 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041833046&doi=10.1002%2fslct.201700517&partnerID=40&md5=7672d87bc53e298bcf65d4ce3f2d2fb3

 

DOI: 10.1002/slct.201700517

 

Badavath, V.N., Jadav, S.S., Pastorino, B., De Lamballerie, X., Sinha, B.N., Jayaprakash, V.

Synthesis and antiviral activity of 2-aryl-4H-chromen-4-one derivatives against Chikungunya virus

(2016) Letters in Drug Design and Discovery, 13 (10), pp. 1019-1024. Cited 2 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995900405&doi=10.2174%2f1570180813666160711163349&partnerID=40&md5=b77a4230865831d3b528e62e34e166ea

 

DOI: 10.2174/1570180813666160711163349

 

Mule, S.N.R., Nurbhasha, S., Kolla, J.N., Jadav, S.S., Jayaprakash, V., Bhavanam, L.R., Bollikolla, H.B.

Synthesis, biological screening and molecular docking studies of novel 4,6-pyrimidine derivatives as EGFR-TK inhibitors

(2016) Medicinal Chemistry Research, 25 (11), pp. 2534-2546. Cited 4 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981293966&doi=10.1007%2fs00044-016-1668-x&partnerID=40&md5=7c6325e1096f10ba49b6811396ae8dd4

 

DOI: 10.1007/s00044-016-1668-x

 

Mathew, B., Haridas, A., Uçar, G., Baysal, I., Adeniyi, A.A., Soliman, M.E.S., Joy, M., Mathew, G.E., Lakshmanan, B., Jayaprakash, V.

Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors

(2016) International Journal of Biological Macromolecules, 91, pp. 680-695. Cited 22 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84974851890&doi=10.1016%2fj.ijbiomac.2016.05.110&partnerID=40&md5=6638de2299a24ef1d7a875450c08b358

 

DOI: 10.1016/j.ijbiomac.2016.05.110

 

Thakur, A., Dan, N., Bhakat, S., Jayaprakash, V., Banerjee, S.

5' adenosine monophosphate-activated protein kinase modulators as anticancer agents

(2016) Anti-Cancer Agents in Medicinal Chemistry, 16 (8), pp. 961-972. Cited 1 time.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981489379&doi=10.2174%2f1871520616666160211124240&partnerID=40&md5=db73c9a32d875d1dc7935c80ab96204f

 

DOI: 10.2174/1871520616666160211124240

 

Mathew, B., Haridas, A., Suresh, J., Mathew, G.E., Uçar, G., Jayaprakash, V.

Monoamine oxidase inhibitory action of chalcones: A Mini Review

(2016) Central Nervous System Agents in Medicinal Chemistry, 16 (2), pp. 120-136. Cited 19 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973649627&doi=10.2174%2f1871524915666151002124443&partnerID=40&md5=1d7201c08cdd39f0c2c8b2a8a2a25cc8

 

DOI: 10.2174/1871524915666151002124443

 

Mathew, B., Mathew, G.E., Uçar, G., Baysal, I., Suresh, J., Mathew, S., Haridas, A., Jayaprakash, V.

Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives

(2016) Chemistry and Biodiversity, pp. 1046-1052. Cited 9 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983032366&doi=10.1002%2fcbdv.201500367&partnerID=40&md5=483057f31e08503caf990904b105f9b5

 

DOI: 10.1002/cbdv.201500367

 

Mathew, B., Mathew, G.E., Suresh, J., Ucar, G., Sasidharan, R., Anbazhagan, S., Vilapurathu, J.K., Jayaprakash, V.

Monoamine oxidase inhibitors: Perspective design for the treatment of depression and neurological disorders

(2016) Current Enzyme Inhibition, 12 (2), pp. 115-122. Cited 7 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981742462&doi=10.2174%2f1573408012666160402001715&partnerID=40&md5=024e9efd2f7156e1ff363c41ea89e73f

 

DOI: 10.2174/1573408012666160402001715

 

Timiri, A.K., Sinha, B.N., Jayaprakash, V.

Progress and prospects on DENV protease inhibitors

(2016) European Journal of Medicinal Chemistry, 117, pp. 125-143. Cited 14 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84963808195&doi=10.1016%2fj.ejmech.2016.04.008&partnerID=40&md5=31ad389e52b923dfd90c41b22655685f

 

DOI: 10.1016/j.ejmech.2016.04.008

 

Badavath, V.N., Baysal, I., Ucar, G., Sinha, B.N., Jayaprakash, V.

Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis

(2016) ACS Medicinal Chemistry Letters, 7 (1), pp. 56-61. Cited 21 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955480132&doi=10.1021%2facsmedchemlett.5b00326&partnerID=40&md5=a5210867b5f00cca49abf19c1eaa8142

 

DOI: 10.1021/acsmedchemlett.5b00326

 

Yasmin, S., Jayaprakash, V.

Design, in silico docking and predictive ADME properties of some thiazolidine-2, 4-diones derivatives as PPARγ modulators

(2016) International Journal of Pharmacy and Pharmaceutical Sciences, 8 (5), pp. 143-150. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964854585&partnerID=40&md5=34d3bfacc358c082834bb37e6083b960

 

 

Badavath, V.N., Ucar, G., Sinha, B.N., Mondal, S.K., Jayaprakash, V.

Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis-II

(2016) ChemistrySelect, 1 (18), pp. 5879-5884. Cited 3 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85023183371&doi=10.1002%2fslct.201600914&partnerID=40&md5=78d9f555de409baaa328eee6c846acf7

 

DOI: 10.1002/slct.201600914

 

Badavath, V.N., Baysal, I., Uçar, G., Mondal, S.K., Sinha, B.N., Jayaprakash, V.

Monoamine Oxidase Inhibitory Activity of Ferulic Acid Amides: Curcumin-Based Design and Synthesis

(2016) Archiv der Pharmazie, 349 (1), pp. 9-19. Cited 9 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955328643&doi=10.1002%2fardp.201500317&partnerID=40&md5=921a7c3699f1e9f009c3ad4f75c15177

 

DOI: 10.1002/ardp.201500317

 

Subasri, S., Timiri, A.K., Barji, N.S., Jayaprakash, V., Vijayan, V., Velmurugan, D.

Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(3-nitrophenyl)acetamide monohydrate and N-(2-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide

(2016) Acta Crystallographica Section E: Crystallographic Communications, 72, pp. 1171-1175. Cited 3 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983002477&doi=10.1107%2fS2056989016011658&partnerID=40&md5=f8c3a2d4766e7649865956758e6fd715

 

DOI: 10.1107/S2056989016011658

 

Mohd Siddique, M.U., McCann, G.J.P., Sonawane, V., Horley, N., Williams, I.S., Joshi, P., Bharate, S.B., Jayaprakash, V., Sinha, B.N., Chaudhuri, B.

Biphenyl urea derivatives as selective CYP1B1 inhibitors

(2016) Organic and Biomolecular Chemistry, 14 (38), pp. 8931-8936. Cited 12 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84989162902&doi=10.1039%2fc6ob01506a&partnerID=40&md5=e002e72762872d691d8628ebd8f4836f

 

DOI: 10.1039/c6ob01506a

 

Mathew, B., Haridas, A., Uçar, G., Baysal, I., Joy, M., Mathew, G.E., Lakshmanan, B., Jayaprakash, V.

Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors

(2016) ChemMedChem, pp. 1161-1171. Cited 16 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973622864&doi=10.1002%2fcmdc.201600122&partnerID=40&md5=909dfae534294988f971c68077143be0

 

DOI: 10.1002/cmdc.201600122

 

Hatti, I., Sreenivasulu, R., Jadav, S.S., Jayaprakash, V., Kumar, C.G., Raju, R.R.

Synthesis, cytotoxic activity and docking studies of new 4-aza-podophyllotoxin derivatives

(2015) Medicinal Chemistry Research, 24 (8), pp. 3305-3313. Cited 18 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937813494&doi=10.1007%2fs00044-015-1375-z&partnerID=40&md5=36cf8b608d04f7cfff69cc1dd5049cd4

 

DOI: 10.1007/s00044-015-1375-z

 

Timiri, A.K., Subasri, S., Kesherwani, M., Vishwanathan, V., Sinha, B.N., Velmurugan, D., Jayaprakash, V.

Synthesis and molecular modelling studies of novel sulphonamide derivatives as dengue virus 2 protease inhibitors

(2015) Bioorganic Chemistry, 62, art. no. 1832, pp. 74-82. Cited 11 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84938489701&doi=10.1016%2fj.bioorg.2015.07.005&partnerID=40&md5=ddd0fc413e40dd8f3624a60b5a7d5b98

 

DOI: 10.1016/j.bioorg.2015.07.005

 

Jadav, S.S., Kaptein, S., Timiri, A., De Burghgraeve, T., Badavath, V.N., Ganesan, R., Sinha, B.N., Neyts, J., Leyssen, P., Jayaprakash, V.

Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus e protein inhibitors

(2015) Bioorganic and Medicinal Chemistry Letters, 25 (8), pp. 1747-1752. Cited 12 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84940003248&doi=10.1016%2fj.bmcl.2015.02.059&partnerID=40&md5=21b420ee4b17e248144171c2a24e0ee2

 

DOI: 10.1016/j.bmcl.2015.02.059

 

Badavath, V.N., Sinha, B.N., Jayaprakash, V.

Design, in-silico docking and predictive adme properties of novel pyrazoline derivatives with selective human MAO inhibitory activity

(2015) International Journal of Pharmacy and Pharmaceutical Sciences, 7 (12), pp. 277-282. Cited 3 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949754723&partnerID=40&md5=ee4f51d0ec247eefe88177a789c71d75

 

 

Jadav, S.S., Kumar, A., Ahsan, M.J., Jayaprakash, V.

Ebola virus: Current and future perspectives

(2015) Infectious Disorders - Drug Targets, 15 (1), pp. 20-31. Cited 3 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930890909&doi=10.2174%2f1871526515666150320162259&partnerID=40&md5=72c3f76329c049bd0f9d9484d259fbdb

 

DOI: 10.2174/1871526515666150320162259

 

Jadav, S.S., Sinha, B.N., Pastorino, B., De Lamballerie, X., Hilgenfeld, R., Jayaprakash, V.

Identification of pyrazole derivative as an antiviral agent against chikungunya through HTVS

(2015) Letters in Drug Design and Discovery, 12 (4), pp. 292-301. Cited 8 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84926452429&partnerID=40&md5=29fd5a88a269bc5455614d488232a79a

 

 

Bhakat, S., Delang, L., Kaptein, S., Neyts, J., Leyssen, P., Jayaprakash, V.

Reaching beyond HIV/HCV: Nelfinavir as a potential starting point for broad-spectrum protease inhibitors against dengue and chikungunya virus

(2015) RSC Advances, 5 (104), pp. 85938-85949. Cited 5 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944754654&doi=10.1039%2fc5ra14469h&partnerID=40&md5=55dd0787ce16341332e22eacaae94c16

 

DOI: 10.1039/c5ra14469h

 

Alavala, R.R., Kulandaivelu, U., Bonagiri, P., Boyapati, S., Jayaprakash, V., Subramaniam, A.T.

Synthesis and antiviral activity of dihydropyrimidines – ciprofloxacin mannich bases against various viral strains

(2015) Anti-Infective Agents, 13 (2), pp. 154-165. Cited 1 time.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960959402&partnerID=40&md5=c1447d473911069026dbc3500d908216

 

 

Nayak, B.V., Ciftci-Yabanoglu, S., Bhakat, S., Timiri, A.K., Sinha, B.N., Ucar, G., Soliman, M.E.S., Jayaprakash, V.

Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones

(2015) Bioorganic Chemistry, 58, pp. 72-80. Cited 19 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919725488&doi=10.1016%2fj.bioorg.2014.11.008&partnerID=40&md5=2d5b0aa8c3a5a1706e7eb272304d8256

 

DOI: 10.1016/j.bioorg.2014.11.008

 

Bhakat, S., Karubiu, W., Jayaprakash, V., Soliman, M.E.S.

A perspective on targeting non-structural proteins to combat neglected tropical diseases: Dengue, West Nile and Chikungunya viruses

(2014) European Journal of Medicinal Chemistry, 87, pp. 677-702. Cited 22 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908030336&doi=10.1016%2fj.ejmech.2014.10.010&partnerID=40&md5=97cd4a41ea96e045e9282fa738d3a655

 

DOI: 10.1016/j.ejmech.2014.10.010

 

Rathinavelusamy, P., Mazumder, P.M., Sasmal, D., Jayaprakash, V.

Evaluation of in silico, in vitro α-amylase inhibition potential and antidiabetic activity of Pterospermum acerifolium bark

(2014) Pharmaceutical Biology, 52 (2), pp. 199-207. Cited 3 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891786739&doi=10.3109%2f13880209.2013.823551&partnerID=40&md5=b666448d88e80eb7f0da886a06ad599d

 

DOI: 10.3109/13880209.2013.823551

 

Bojanapu, A., Subramaniam, A.T., Munusamy, J., Dhanapal, K., Chennakesavalu, J., Sellappan, M., Jayaprakash, V.

Validation and method development of tadalafil in bulk and tablet dosage form by RP-HPLC

(2014) Drug Research, 65 (2), pp. 82-85. Cited 3 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923567123&doi=10.1055%2fs-0034-1372608&partnerID=40&md5=be8b8fbad6b611fb466177b362ec8458

 

DOI: 10.1055/s-0034-1372608

 

Paramaguru, R., Mazumder, P.M., Sasmal, D., Jayaprakash, V.

Antidiabetic activity of pterospermum acerifolium flowers and glucose uptake potential of bioactive fraction in l6 muscle cell lines with its HPLC fingerprint

(2014) BioMed Research International, 2014, art. no. 459376, . Cited 4 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84911191808&doi=10.1155%2f2014%2f459376&partnerID=40&md5=5c3c8d65034e8f5d01ca2d797c58e6b1

 

DOI: 10.1155/2014/459376

 

Subasri, S., Kumar, T.A., Sinha, B.N., Jayaprakash, V., Velmurugan, D.

2-[(4,6-Diaminopyrimidin-2-yl)sulfanyl]-N-(2-methylphenyl)acetamide

(2014) Acta Crystallographica Section E: Structure Reports Online, 70 (8), pp. o850. Cited 4 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905482191&doi=10.1107%2fS1600536814015256&partnerID=40&md5=e29c17ff1b6753cc53961ded4ff38606

 

DOI: 10.1107/S1600536814015256

 

Jadav, S.S., Sinha, B.N., Hilgenfeld, R., Pastorino, B., De Lamballerie, X., Jayaprakash, V.

Thiazolidone derivatives as inhibitors of chikungunya virus

(2014) European Journal of Medicinal Chemistry, 89, pp. 172-178. Cited 21 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908447953&doi=10.1016%2fj.ejmech.2014.10.042&partnerID=40&md5=d08cb96cf588abb87370e68ac7d1c2c2

 

DOI: 10.1016/j.ejmech.2014.10.042

 

Kulandaivelu, U., Chilakamari, L.M., Jadav, S.S., Rao, T.R., Jayaveera, K.N., Shireesha, B., Hauser, A.-T., Senger, J., Marek, M., Romier, C., Jung, M., Jayaprakash, V.

Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8

(2014) Bioorganic Chemistry, 57, pp. 116-120. Cited 4 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907930844&doi=10.1016%2fj.bioorg.2014.08.005&partnerID=40&md5=addc698a913a5703be843f09c776e7ba

 

DOI: 10.1016/j.bioorg.2014.08.005

 

Vishnu Nayak, B., Ciftci-Yabanoglu, S., Jadav, S.S., Jagrat, M., Sinha, B.N., Ucar, G., Jayaprakash, V.

Monoamine oxidase inhibitory activity of 3,5-biaryl-4,5-dihydro-1H- pyrazole-1-carboxylate derivatives

(2013) European Journal of Medicinal Chemistry, 69, pp. 762-767. Cited 30 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884919003&doi=10.1016%2fj.ejmech.2013.09.010&partnerID=40&md5=1acaed512fe8635e1929968ee79f56bc

 

DOI: 10.1016/j.ejmech.2013.09.010

 

Mahapatra, M., Kulandaivelu, U., Saiko, P., Graser, G., Szekeres, T., Andrei, G., Snoeck, R., Balzarini, J., Jayaprakash, V.

Methyl-2-arylidene hydrazinecarbodithioates: Synthesis and biological activity

(2013) Chemical Papers, 67 (6), pp. 650-656. Cited 2 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879690639&doi=10.2478%2fs11696-013-0346-4&partnerID=40&md5=e502c3e2dc145df4115dda13c6e2cc17

 

DOI: 10.2478/s11696-013-0346-4

 

Kulandaivelu, U., Shireesha, B., Mahesh, C., Vidyasagar, J.V., Rao, T.R., Jayaveera, K.N., Saiko, P., Graser, G., Szekeres, T., Jayaprakash, V.

Synthesis antimicrobial and anticancer activity of N′- arylmethylidene-piperazine-1-carbothiohydrazide

(2013) Medicinal Chemistry Research, 22 (6), pp. 2802-2808. Cited 6 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879688615&doi=10.1007%2fs00044-012-0279-4&partnerID=40&md5=b9e13aad327c498cb3b50d0181fd9633

 

DOI: 10.1007/s00044-012-0279-4

 

Ferreras, J.A., Gupta, A., Amin, N.D., Basu, A., Sinha, B.N., Worgall, S., Jayaprakash, V., Quadri, L.E.N.

Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis

(2011) Bioorganic and Medicinal Chemistry Letters, 21 (21), pp. 6533-6537. Cited 6 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054786404&doi=10.1016%2fj.bmcl.2011.08.052&partnerID=40&md5=767c5af2e4e19c6b0f2396b5969f09c4

 

DOI: 10.1016/j.bmcl.2011.08.052

 

Jagrat, M., Behera, J., Yabanoglu, S., Ercan, A., Ucar, G., Sinha, B.N., Sankaran, V., Basu, A., Jayaprakash, V.

Pyrazoline based MAO inhibitors: Synthesis, biological evaluation and SAR studies

(2011) Bioorganic and Medicinal Chemistry Letters, 21 (14), pp. 4296-4300. Cited 34 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959891957&doi=10.1016%2fj.bmcl.2011.05.057&partnerID=40&md5=5a3d68f80688cdf129775ee7895a6b7b

 

DOI: 10.1016/j.bmcl.2011.05.057

 

Kulandaivelu, U., Padmini, V.G., Suneetha, K., Shireesha, B., Vidyasagar, J.V., Rao, T.R., Jayaveera, K.N., Basu, A., Jayaprakash, V.

Synthesis, antimicrobial and anticancer activity of new thiosemicarbazone derivatives

(2011) Archiv der Pharmazie, 344 (2), pp. 84-90. Cited 20 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-79551696597&doi=10.1002%2fardp.201000201&partnerID=40&md5=9624489b34c5407af3ecc226fe9376b3

 

DOI: 10.1002/ardp.201000201

 

Saiko, P., Graser, G., Giessrigl, B., Lackner, A., Grusch, M., Krupitza, G., Basu, A., Sinha, B.N., Jayaprakash, V., Jaeger, W., Fritzer-Szekeres, M., Szekeres, T.

A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C)

(2011) Biochemical Pharmacology, 81 (1), pp. 50-59. Cited 11 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-78549281372&doi=10.1016%2fj.bcp.2010.09.006&partnerID=40&md5=374e13a8f66e471c7c310764436028f4

 

DOI: 10.1016/j.bcp.2010.09.006

 

Jayaprakash, V., Yabanoglu, S., Sinha, B.N., Ucar, G.

Pyrazoline-based mycobactin analogues as dual inhibitors of MAO/cholinesterase [MAO ve kolinesteraz dual i?nhibitörü pirazolin-bazli mikobaktin analoglari]]

(2010) Turkish Journal of Biochemistry, 35 (2), pp. 91-98. Cited 11 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954755639&partnerID=40&md5=2bc3178d3678011bdc01242d93556af2

 

 

Chetan, B., Bunha, M., Jagrat, M., Sinha, B.N., Saiko, P., Graser, G., Szekeres, T., Raman, G., Rajendran, P., Moorthy, D., Basu, A., Jayaprakash, V.

Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity

(2010) Bioorganic and Medicinal Chemistry Letters, 20 (13), pp. 3906-3910. Cited 40 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954315435&doi=10.1016%2fj.bmcl.2010.05.020&partnerID=40&md5=4a4b4a85395b8eea308dc518d1d7afc1

 

DOI: 10.1016/j.bmcl.2010.05.020

 

Mishra, N., Oraon, A., Dev, A., Jayaprakash, V., Basu, A., Pattnaik, A.K., Tripapthi, S.N., Akhtar, M., Ahmad, S., Swaroop, S., Basu, M.

Anticonvulsant activity of Benkara malabarica (Linn.) root extract: In vitro and in vivo investigation

(2010) Journal of Ethnopharmacology, 128 (2), pp. 533-536. Cited 11 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-77649342571&doi=10.1016%2fj.jep.2010.01.042&partnerID=40&md5=e142e73960c84d7e718d8b639c051da8

 

DOI: 10.1016/j.jep.2010.01.042

 

Karuppasamy, M., Mahapatra, M., Yabanoglu, S., Ucar, G., Sinha, B.N., Basu, A., Mishra, N., Sharon, A., Kulandaivelu, U., Jayaprakash, V.

Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies

(2010) Bioorganic and Medicinal Chemistry, 18 (5), pp. 1875-1881. Cited 39 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-77349110399&doi=10.1016%2fj.bmc.2010.01.043&partnerID=40&md5=0653a9f13c6411b63ac4265a63a12704

 

DOI: 10.1016/j.bmc.2010.01.043

 

Chakrabarty, S., Jasmine, Bhadaliya, C., Sinha, B.N., Mahesh, A., Bai, H., Blond, S.Y., Jayaprakash, V.

Inhibitors of human histone deacetylase: Synthesis and enzyme assay of hydroxamates with piperazine linker

(2010) Archiv der Pharmazie, 343 (3), pp. 167-172. Cited 5 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-77949376273&doi=10.1002%2fardp.200900117&partnerID=40&md5=673a49362823d4348c5924aab33a7323

 

DOI: 10.1002/ardp.200900117

 

Sahoo, A., Yabanoglu, S., Sinha, B.N., Ucar, G., Basu, A., Jayaprakash, V.

Towards development of selective and reversible pyrazoline based MAO-inhibitors: Synthesis, biological evaluation and docking studies

(2010) Bioorganic and Medicinal Chemistry Letters, 20 (1), pp. 132-136. Cited 55 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-72149094342&doi=10.1016%2fj.bmcl.2009.11.015&partnerID=40&md5=93817683a5dc694fd3b5196c396c2fa3

 

DOI: 10.1016/j.bmcl.2009.11.015

 

Mishra, N., Basu, A., Jayaprakash, V., Sharon, A., Basu, M., Patnaik, K.K.

Structure based virtual screening of GSK-3β: Importance of protein flexibility and induced fit

(2009) Bioorganic and Medicinal Chemistry Letters, 19 (19), pp. 5582-5585. Cited 7 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-70049111237&doi=10.1016%2fj.bmcl.2009.08.042&partnerID=40&md5=1c2264150497634fac066ad40a6848bc

 

DOI: 10.1016/j.bmcl.2009.08.042

 

Basu, A., Jasu, K., Jayaprakash, V., Mishra, N., Ojha, P., Bhattacharya, S.

Development of CoMFA and CoMSIA models of cytotoxicity data of anti-HIV-1-phenylamino-1H-imidazole derivatives

(2009) European Journal of Medicinal Chemistry, 44 (6), pp. 2400-2407. Cited 33 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-64249142581&doi=10.1016%2fj.ejmech.2008.09.043&partnerID=40&md5=53ab804277bababe033bdf36fc25127c

 

DOI: 10.1016/j.ejmech.2008.09.043

 

Jayaprakash, V., Sinha, B.N., Ucar, G., Ercan, A.

Pyrazoline-based mycobactin analogues as MAO-inhibitors

(2008) Bioorganic and Medicinal Chemistry Letters, 18 (24), pp. 6362-6368. Cited 48 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-56249144473&doi=10.1016%2fj.bmcl.2008.10.084&partnerID=40&md5=0e39c962a4a7107a28ed6830560ee654

 

DOI: 10.1016/j.bmcl.2008.10.084

 

Dewangan, P., Verma, S.M., Basu, A., Venkatesan, J.

Multidimensional consensus QSAR: A step towards integrating CoMFA, CoMSIA with traditional QSAR methodologies

(2008) Letters in Drug Design and Discovery, 5 (8), pp. 494-502. Cited 1 time.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-58049199411&doi=10.2174%2f157018008786898563&partnerID=40&md5=f61881f2ea2035e9ba2a424ae817c0cd

 

DOI: 10.2174/157018008786898563

 

Krishnan, K., Prathiba, K., Jayaprakash, V., Basu, A., Mishra, N., Zhou, B., Hu, S., Yen, Y.

Synthesis and Ribonucleotide reductase inhibitory activity of thiosemicarbazones

(2008) Bioorganic and Medicinal Chemistry Letters, 18 (23), pp. 6248-6250. Cited 26 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-55549087863&doi=10.1016%2fj.bmcl.2008.09.097&partnerID=40&md5=9d80bde005cd5d89f30407de2dc2f604

 

DOI: 10.1016/j.bmcl.2008.09.097

 

Stirrett, K.L., Ferreras, J.A., Jayaprakash, V., Sinha, B.N., Ren, T., Quadri, L.E.N.

Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis

(2008) Bioorganic and Medicinal Chemistry Letters, 18 (8), pp. 2662-2668. Cited 47 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-41849151739&doi=10.1016%2fj.bmcl.2008.03.025&partnerID=40&md5=f3a649388a47041a219bfae8a5e94f44

 

DOI: 10.1016/j.bmcl.2008.03.025

 

Venkatesan, J., Pandeya, S., Selvakumar, D.

Synthesis and biological evaluation of 4,6-diaryl substituted-4,5-dihydro- 2-amino pyrimidines

(2007) Indian Journal of Pharmaceutical Sciences, 69 (4), pp. 586-589. Cited 7 times.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-36048969267&partnerID=40&md5=d3ab65893db75e5329b184ebc5d125ef

 

 

Venkatesan, J., Pandeya, S.N., Selvakumar, D., Babuthandapani, A.

Synthesis and biological evaluation of 4,6-diaryl substituted- 4,5-dihydro pyrimidinyl-2-ureas

(2005) Indian Drugs, 42 (7), pp. 447-452. 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955458150&partnerID=40&md5=2ba54ac207a617a92407adfd48b4f6bf

 

  Member of Professional Bodies
 

  • Registered Pharmacist (17905 A2), Tamilnadu Pharmacy Council, Vadapalani, Chennai-600026 (TN), India
  • APTI Life Member (TN/LM-187), H.Q: No.620 D, 35th Cross, 2nd Block, Rajajinagar, Bengaluru-560 010 (KA), India

  Current Sponsored Projects
 

Research Grants

 

Co-Principal Investigator

Title: Design and Synthesis of Substrate Based Peptide Inhibitors of DENV Protease for the Treatment of Dengue Viral Infections

Principal Investigator: Dr. Barij Nayan Sinha & Co-Principal Investigator: Dr. B. Sarkar

Scheme & Agency: EMR (Individual Centric), Science & Engineering Research Board, DST,  Govt. of India, India

File No.: EMR/2016/005711

Amount Sanctioned: 45,60,400/-

Duration: Three years (2017-2020)

 

Principal Investigator

Title: Phenyloxazoline Synthetase Inhibitors as Antitubercular Agents (POSIAA)

Co-Principal Investigator: Dr. Abhimanyu Dev

Scheme & Agency: EMR (Individual Centric), Science & Engineering Research Board, DST,  Govt. of India, India

File No.: EMR/2016/000675

Amount Sanctioned: 53,73,450/-

Duration: Three years (2016-2019)

 

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Design & Synthesis of potent dual inhibitors of Cdk-4 and tubulin as anticancer agents

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: An Indo-UK Project sponsored by University Grants Commission (UGC), Govt. of India, India

Amount Sanctioned: 30,88,800/-

Duration: Two years (2013-2015)

 

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Structure-based discovery of antivirals for the treatment of Chikungunya virus infections (Anti-Chick)

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: New-Indigo Eranet, An Indo-German Project sponsored by Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India

Amount Sanctioned: 34,62,000/-

Duration: (Two Years) 2011-2013

 

Research Group Member & Co-supervisor for the scholar enrolled under the project

Title: Structure-based design of Dengue virus protease inhibitors

Principle Investigator: Prof. B. N. Sinha

Scheme & Agency: An Indo-German Project sponsored by Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India

Amount Sanctioned: 24,51,800/-

Duration: (3 Years) 2011-2014

 

Co-principle Investigator

Title: Grid-based Virtual Screening for TB (Grid-ViSiT)

Principle Investigator: K. K. Patnaik, Dept. of Comp. Sci. Engg., BIT, Mesra

Scheme & Agency: Research Promotion Scheme (RPS) sponsored by All IndiaCouncil for Technical Education (AICTE), Govt. of India, India

Amount Sanctioned: Rs. 6,50,000/-

Duration: (Two Years) 2008-2010

 

Travel Grants

 

Travel Grant from DBT (DBT/CTEP/02/201501300)- "International Multidisciplinary Symposium on Drug Research and Development" organized by Anadolu University Ataturk Culture & Arts Centre, Eskisehir, Turkey, 15-17 October, 2015

 


  Text and Refrence Books
 

Book

Venkatesan Jayaprakash, Barij Nayan Sinha, Anti-tubercular Drug Design Exploring Mycobactin Biosynthetic Pathway, Designing molecules that mimics hydroxyphenyl oxazoline portion of mycobactin, LAP Lambert Academic Publication, Germany, 2013 (ISBN:978-3-659-43995-7)

Book Chapter

Venkatesan Jayaprakash, Ajay Kumar Timiri, Barij Nayan Sinha, "Studies on Inhibitors of Dengue Virus Protease", Advances in Studies on Enzyme Inhibitors As Drugs: Anticancer and Antiviral Drugs, Vol. I, Editor, S. P. Gupta, Nova Science Publisher Inc., New York, 2017(ISBN:978-1-53610-504-9)


  Patent
 
  • Application No. 325/KOL/2014 A; Title: 2-(4,6-diaminopyrimidin-2-ylthio)-N-aryl acetamide derivatives, their synthesis, antiviral activity and methods thereof
  • Application No. 191/KOL/2014 A; Title: 4-(1,3-dioxoisoindolin-2-yl)-benzenesulfonamide derivatives, their synthesis, antiviral activity and methods thereof
  • Application No. 811/KOL/2013; Title: Arylmethylidene heterocyclics as novel antiviral agents against chikungunya viral infection
  • Application No. 349/CHE/2011; Title: Dihydropyrimidine Derivatives as pharmacologically active agents

  Fellow
 
  • 1997-1999, Junior Research Fellowship, University Grants Commission, Government of India

  Member, Editorial Board
 

Editor: Journal of Pharmaceutical Chemistry (ISSN: 2349-5731)

Editorial Board Member: PHARMBIT (ISSN: 0973-6204)