Birla Institute of Technology, Mesra
   
Dr. (MS) S. Ganguly
Professor, Pharmaceutical Sciences and Tech
M. Pharm., Ph.D., FIC, FICS
Contact Address
Permanent Address Flat 416, Kaveri-3, Trivenipuram,Booty More, NH-33, Ranchi-835217
Local Address Department of Pharmaceutical Sciences, BIT, Mesra, Ranchi-835215
Phone (Office) 0651-2276247
Phone Residence 9431327042
Email Id swastikaganguly@bitmesra.ac.in
Joined Institute on : 28-Mar-2001
  Work Experience
 
Teaching : 16 Years

Research : 20 Years

  Research Areas
 

       Synthesis and Evaluation of New Chemical Entities with special reference to heterocyclic moieties :

 

Brief description of work done:

 

Various novel analogs of imidazoles, 2-methylimidazoles and 2-methyl-5-nitroimidazoles have been synthesized, characterized and evaluated for their antibacterial, antifungal, antidiarrheal, anticonvulsant and miscellaneous other activities.1- substituted imidazoles, 2-methylimidazoles and 2-methyl-5-nitroimidazoles have showed interesting activities in the field of antimycobacterial , anti fungal , anticonvulsant and  antihypertensive research.

The benzimidazole scaffold has also been used for synthesis of novel mercaptobenzimidazoles attached to the quinazoline moiety which have been evaluated for their antiulcer activity. It is worth noting that some of the novel benzimidazoles have shown potent antiulcer activities.

Similarly, novel quinazolines have been synthesized which have shown very high activities against influenza virus and herpes viruses.

   

·         Insiilco  Design, Synthesis and Evaluation of antiHIV  agents.

 

Brief description of work done:

 

Three dimensional QSAR as well as docking studies of various HIV-1- RT inhibitors, particularly non nucleoside reverse transcriptase inhibitors have been carried out. Based on the QSAR and modelling studies , various heterocyclic moieties for e.g. tetrahydroquinolines and tetrahydroisoquinolines, N-aminoimidazoles, thiazolidinediones, tetrazoles, , bernzotriazoles, and benzimidazoles have been used as scaffolds for the design and synthesis of novel analogs of these heterocycles which have been evaluated for HIV-1 -RT inhibitory activities along with antimicrobial activities to develop antiHIV agents with broad spectrum chemotherapeutic properties. Some of the N- aminoimidazole analogs have shown interesting activities against the K103N and Y181C resistant strains of HIV.

Encouraging results have also been found with teterahydroquinolines   , tetrahydroisoquinolines and imidazoles as as dual inhibitors, exhibiting both antiHIV and antibacterial properties. Work is also being carried out in the field of HIV integrase inhibitors by modelling, synthesis and evaluation of novel diketo acids.

 

·         Molecular Modeling and Cheminformatics.

 

Brief description of work done:

 

QSAR , modelling  and ADMET studies using various modelling software viz., SYBYL/CoMFA and COMSIA, Schrodinger suite, FlexX, Scigress Explorer Ultra and ADME Works Model Builder for various azoles and tetrahydroquinolines have been carried out to develop predictive and robust models leading to the design of newer azoles with potential antifungal and antiHIV activities.

  Award and Honours
 

 ·   SENIOR RESEARCH FELLOWSHIP by C.S.I.R., New Delhi for 4 years i.e. from 28.07.1994 to 31. 07.1998 and tenable at the Department of Pharmaceutical Sciences, B.I.T., Mesra, Ranchi, Jharkhand.   

·   AL AMEEN COLLEGE OF PHARMACY AWARD for the article entitled “Development of a database for identification of crude drugs”, Indian Journal of Pharmaceutical Education, Jan-March 2005, Vol.39 (1), p 38-41.

·   Fellow of the Institution of Chemists (INDIA).

·   Elected Chartered Chemist of the Institution of Chemists (INDIA).

·   Ph.D. Examiner for Department of Pharmaceutical Sciences, Kakatiya University, Warrangal and Birla Institute of Technology and Science, Pilani, Rajasthan.

·   Examiner and paper setter for various Universities viz., B. R. Ambedkar University, University of Jodhpur

·   Reviewer of International Journals Tetrahedron Letters, European Journal of Medicinal Chemistry, Medicinal Chemistry Research and many national journals.

·   Nominated as an Expert Member of AICTE, 2013.

 

   Publications
 

 Publications of last five years:

LIST OF PUBLICATIONS OF DR.S.GANGULY(2008-2013)

 

International:

  • Biplab Debnath & Swastika Ganguly Synthesis, Biological Evaluation, in Silico Docking and Virtual ADME Studies of Novel Isatin Analogs as Promising Antimicrobial Agents, Antiinfective agents (accepted)
  • Biplab Debnath & Swastika Ganguly (2015): Synthesis of Some Novel (2-Oxo-3-(arylimino) indolin-1-yl)-Naryl acetamides and evaluation as Antimicrobial Agents, Toxicological & Environmental Chemistry, DOI: 10.1080/02772248.2015.1061524
  • Swastika Ganguly, Surbhi Mishra, Ira Sankrityayan and Abhimanyu Dev,“Synthesis, antimicrobial activities and binding mode analysis of some novel N-substituted imidazoles and nitroimidazoles”Indian Journal of Heterocyclic Chemistry, 24,Jan-March 2015, pp373-380.
  • Geeta Yadav and Swastika Ganguly, Synthesis, antiHIV , antimicrobial evaluation and structure activity relationship studies of some novel benzimidazole derivatives , Antiinfective agents, 13,2015, 65-77.Geeta Yadav and Swastika Ganguly, Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: a mini-review , Eur. J. Med. Chem, 97 (2015), 419- 443. DOI 10.1016/j.ejmech.2014.11.053,
  • Geeta Yadav , Swastika Ganguly, S. Murugesan and A. Dev,  Anti-HIV and Antimicrobial Activity in vitro of some New benzimidazole derivatives, International Journal of Research in Pharmaceutical Sciences 5(4),2014.243-249.
  • Radhe Shyam Bahare, Swastika Ganguly, Kiattawee Choowongkomon and Supaporn Seetaha, Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2,4-thiazolidinediones,Daru Journal of Pharmaceutical Sciences, DOI 10.1186/s40199-014-0086-1.
  • Biplab Debnath and Swastika Ganguly, Molecular docking studies and ADME prediction of novel isatin analogs as HIV-1-RT inhibitors with broad spectrum chemo therapeutic properties, Asian Journal of Pharmaceutical and Cinical Research, 2014,  7(5 ), 186-194 .
  • Swastika Ganguly and Biplab Debnath, Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity, Medicinal Chemistry, 2014, 4(8), 558-568.
  • Penta Ashok, Swastika Ganguly and Sankaranarayanan Murugesan, Manzamine alkaloids: isolation, cytotoxicity, antimalarial activity and SAR studies, Drug Discovery Today, 2014,19(11) , 1781-1791.
  • Pravinkumar Sable, Swastika Ganguly, Synthesis of Some Thienopyrimidine Derivatives as Antimicrobial Agents, Ind. Jr. Het. Chem, 2014, 23, 245-246.
  • Swastika Ganguly, Nalini Singh and Arpita Upadhyay, Synthesis, antibacterial activities and binding mode analysis of some novel 1,4 diaryl imidazole thiones , Ind. Jr. Het. Chem., April-June 2014, 23, ,419-423.
  • Pravinkumar N. Sable, Swastika Ganguly and  Pravin D. Chaudhari, An efficient one-pot three-component synthesis and antimicrobial evaluation of tetra substituted thiophene derivatives, Chinese Chemical Letters, 2014, (25), 1099–1103.
  • Jagdish Sahu, Swastika Ganguly and Atul Kaushik, Synthesis and antimicrobial activity of some novel fused heterocyclic 1,2,4-triazolo [3,4-b][1,3,4] thiadiazine derivatives, Journal of Advanced Pharmaceutical Technology & Research, Apr-Jun 2014 , 5 (2) ,90-95.
  • Naresh Panigrahi, Swastika Ganguly, Jagadeesh Panda, Y. Praharsha, Ultrasound Assisted Synthesis and Antimicrobial Evaluation of Novel Thiophene Chalcone Derivatives, Chemical Science Transactions, 2014, 3(3), 1163-1171 .
  • Jagdish K. Sahu ,  Swastika Ganguly , Atul Kaushik, Synthesis of Some Novel Fused Heterocyclic 1,2,4-triazolo [3,4-b][1,3,4] Thiadiazole Derivatives as Possible Antimicrobial Agents, Journal of Applied Pharmaceutical Science,  February, 2014,  4 (02), 081-086,
  • AshokPenta, Subhash Chander,  S.Ganguly,  S.Murugesan,  De novo design and in-silico studies of novel 1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid derivatives as HIV-1 reverse transcriptase inhibitors, Med.Chem.Res,. DOI 10.1007/s00044-014-0945-9.
  • Radhe Shyam Bahare and Swastika Ganguly, Effect of Electronegative Groups on the Antimicrobial activity of 3,5 disubstituted thiazolidine 2,4-diones, Antiinfective agents, 2014, 12, 112-119.
  • Subhashish Banerjee, Swastika Ganguly, Kalyan Kumar Sen, Kiattawee Choowongkomon, Supaporn Seetaha, Synthesis, evaluation and binding mode analysis of some novel triazole derivatives as antimicrobials, Journal of Advanced Pharmaceutical Education and Research 2013, 3 ,494-511.
  • Swastika Ganguly, Patel Hardik Sureshchandra and Abhimanyu Dev,Synthesis , antibacterial and antifungal activities of some novel 1-(4,5-dihydro-3,5-diaryl-1H-pyraol-4-yl)-1H-imidazoles, Indian Journal of Heterocyclic Chemistry, Jan-March 2013, 22, 301-304.
  • Sankaranarayanan Murugesan, Ashok Penta, Kakamanu Kishore Babu,  Swastika Ganguly, Lack of human immunodeficiency virus-1 integrase inhibitory activity of novel 3a, 4, 7, 7a-tetrahydro-1H-isoindole-1, 3(2H)-dione derivatives, Journal of Pharmaceutical Negative Results, 2013, 4(1), 13-18.
  • Ashok Penta, S. Ganguly and S. Murugesan, Design and synthesis of 3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-diones as inhibitors of HIV-1 reverse transcriptase, International Journal of Pharmacy & Pharmaceutical Sciences 2013,  5(3), 659-664.
  • Ashok Penta, S. Ganguly and S. Murugesan, Design, synthesis and evaluation of 2-(1,3-dioxoisoindolin-2-yl)-N-phenylacetamides as Inhibitors of Reverse Transcriptase,Der Pharmacia Chimica 2013, 5(4), 10-19.
  • P.A. Shok, S. Ganguly and S. Murugesan, Review on in-vitro anti-malarial activity of natural -carboline alkaloids, Mini Reviews in Medicinal Chemistry, 13, 2013,  DOI :10.2174/1389557511313120008  
  • Ashok Penta , Swastika Ganguly and Murugesan Sankaran , Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 Reverse Transcriptase,Organic Medicinal Chemistry Letters, 2013, 3:8,1-8
  • Subhashish banerjee, Swastika Ganguly and Kalyan Kumar Sen, A Review on 1,2,4-Triazoles, Journal of Advanced Pharmaceutical Education and Research ,July-Sept 2013 , 3, 101-115.
  • Jagdish K. Sahu,  Swastika Ganguly, Atul Kaushik, Triazoles: A Valuable Insight into the Recent Development and Biological Activities, Chinese Journal of Natural Medicines, 2013, 11(5),456-465
  • Krishnan Suresh Kumar, Swastika Ganguly, K. Vijayapandi and      , “Synthesis, antiviral and cytotoxic investigations of 2-(4-chlorophenyl)-3-substituted quinazolin-4(3H) ones” International Journal of Drug Design, January–March 2012, 3(1),702-712.
  • Rahul Mystry and Swastika Ganguly, “Imidazole as an antiepileptic”, Medicinal Chemistry Research, DOI 10.1007/s00044-009-9191-y
  • Rahul Mishra, Swastika Ganguly, Kalyan Kumar Sethi and Papiya Mitra Mazumder, “Synthesis and Anticonvulsant Activity of Some Novel 2-Methyl Imidazole Derivatives” , Letters in Drug Design and Discovery, 2012, 9,402-408.
  • Swastika Ganguly, B.S. Nagraj and D. Sriram, Synthesis, antimycobacterial activities and docking studies of some novel diarylimidazoles tareted at mycobacterium tuberculosis p-450DM, Indian Journal of Heterocyclic Chemistry, April-June 2012, 21, 321-330.
  • Nagaraj Selvaraj, Swastika Ganguly, Comparative Molecular Similarity Indices Analysis of Some 1-Substituted Imidazole Analogues as Candida Albicans P450 – Demethylase Inhibitors , Med. Chem. Res. DOI 10.1007/s00044-012-0251-3P.
  • Ashok, Kakumanu Kishore Babu, S. Murugesan and S. Ganguly, Design and Docking Studies of Some Novel 1-Phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acids as Inhibitors of Human Immunodeficiency Virus Type-1 Reverse Transcriptase, Asian Journal of Chemistry; 2012, 24( 12),5857-5860.
  • Swastika Ganguly, Radhe Shyam Bahare, Molecular docking studies of some novel thiazolidinedione analogs as HIV-1-RT inhibitors, Med. Chem. Res. DOI 10.1007/s00044-012-0339-9.
  • Isaac, Jinu, Kaity, Santanu, Ganguly, Swastika, Ghosh, Animesh , Microwave induced solid dispersion technology to improve bioavailability of Glipizide" , Journal of Pharmacy and Pharmacology, DOI: 10.1111/j.2042-7158.2012.01595.x.
  • S Banerjee, S. Ganguly and K. K. Sen, Denovo insilico design of triazole analogs as reverse transcriptase inhibitors, Der Pharmacia Lettre, 2012, 4 (6), 1888-1900
  • S.K. Krishnan, S. Ganguly, R. Veerasamy, B. Jan, “Synthesis, antiviral and cytotoxic Investigation of 2-Phenyl-3-Substituted Quinazolin-4(3h)-ones, European Review for Medical and Pharmacological Sciences”, 15, 2011, 673-682.
  • Swastika Ganguly, Vatsal Vijay Vithlani, Anup Kr. Kesharwani, Ritu Kuhu, Baskar L, Papiya Mitramazumder, Ashok Sharon and Abhimanyu Dev, Synthesis , antibacterial   and potential anti-HIV activity of some novel imidazole analogs, Acta Pharm, 2011, 61,187-201
  • Baskar Lakshamanan, Papiya MitraMazumder, D. Sasmal, S. Ganguly and Simon Santosh Jena, In vitro anthelmentic activity of some 1-substituted imidazoles derivatives , Acta parasitologica Globalis, 2011, 2(1), 01-05.
  • Baskar L, Papiya Mitramazumder, D. Sasmal, Swastika Ganguly, Synthesis, antispasmodic and antidiarrheal activities of some 1-substituted imidazole derivatives, Acta Pharm, 2011, 61,227-236.
  • S. Murugesan and Swastika Ganguly, “3D QSAR - Comparative Molecular Similarity Indices Analysis of 2-Heteroarylquinoline-4-amines as Possible Anti-HIV-1 Agents”, International Journal of Drug Design, April- June 2011, 2(2). 442-451.
  • S. Murugesan and Swastika Ganguly, “Synthesis, evaluation and molecular modeling studies of some novel tetrahydroisoquinoline derivatives targeted at the HIV-1 reverse transcriptase”, Der Pharmacia Lettre, 2011, 3 (6), 317-332.
  • S.Murugesan, S. Ganguly and G. Maga, “Synthesis, evaluation and molecular modeling studies of some novel 3-(3, 4-dihydroisoquinolin-2(1H)-yl)-N-(substituted-phenyl) propanamides as HIV-1 non-nucleoside Reverse Transcriptase Inhibitors”, Journal of Chemical Sciences, March 2010, 122(2), 169-176.
  • Avinash Patil, Swastika Ganguly, Sanjay Surana,Synthesis and antiulcer activity of 2-[5-substituted-1-H-benzo (d) imidazol-2-yl sulfinyl] methyl-3-substituted quinazoline-4-(3H)ones”, Journal of Chemical Sciences May 2010, 122( 3), 443–450.
  • L. Baskar, Papiya Mitra Mazumder, D. Sasmal and Swastika Ganguly, “H2-Receptor Antagonistic Activity of some N-Substituted 2-Methyl Imidazoles”Pharmacologyonline, 2009, 3, 56-63.
  • L. Baskar, Papiya Mitra Mazumder, D. Sasmal And S.Ganguly, “Antispasmodic Effects Of Some Nsubstituted 2-Methyl Imidazole Derivatives on Guinea Pig Ileum”, International Journal Of Pharm Tech Research,2(1), Jan-Mar 2010,760-764.
  • Ponnilavarasan.I, Rajasekaran.A, Sivakumar.K.K, Sundaramoorthi.C, Swastika
  • Ganguly, Sivasakthi.R, ‘Synthetic Approach for the Novel Semicarbazones  of
  • Quinazoline ring and its Biological Activity’ Asian Journal of Research in       Chemistry , April-June 2010,  3(2), 1-5.
  • Poonilavarasan Ilangovan, Swastika Ganguly, Vijay Pandi and James P. Stables, “Design and Synthesis of Novel Quinazolinone derivatives as broad spectrum anticonvulsants” Der Pharmacia Lettre2010, 2 (1),13-21.
  • Swastika Ganguly, Sankaran Murugesan, Naru Prasanthi , Onur Alptürk, Brian Herman  and Nicolas Sluis-Cremer, “Synthesis and Anti-HIV-1 Activity of a Novel Series of Aminoimidazole Analogs”, Letters in Drug Design and Discovery 2010, 7( 5), 318-323.
  • Supriyo Saha, Subhasis Banerjee and Swastika Ganguly, “Molecular Docking Studies Of Some Novel Hydroxamic Acid Derivatives”, International Journal of Chem Tech, 2010, .2, (2), 932-936
  • Krishnan Suresh Kumar, Swastika Ganguly, Ravichandran Veerasamyand Erik De Clercq, “ Synthesis, Antiviral activity and Cytotoxicity Evaluation of Schiff bases of some 2-PhenylQuinazoline-4(3)H-ones”,European Journal of Medicinal Chemistry 2010, 45 ,5474-5479.
  • Baskar Lakshmanan, Papiya Mitra Mazumder, Dinakar Sasmal and Swastika Ganguly, “Biologically Active Azoles: Synthesis, Characterization     and antimicrobial Activity of Some 1-substituted imidazolesDer Pharmacia Lettre, 2010, 2(4), 82-89.
  • Baskar Laxmannan, Papiya Mitramazumder,D. Sasmal and S. Ganguly, “Antiulcer activity of 1-substituted imidazoles against gastric ulcers in rats”,Pharmacologyonline,  2010, 3,503-513.
  • Baskar Lakshmanan, Papiya Mitra Mazumder, Dinakar Sasmal and Swastika Ganguly, “Evaluation of antioxidant potential of Some N-1-Substituted Imidazole Derivatives”, Journal of Global Trends in Pharmaceutical Sciences , Oct –Dec 2010, 1(1), 14- 22.
  • S. Ganguly, Gopalakrishnan V. and R. Chandra, “Synthesis and antibacterial activity of some new 1- substituted 2- methyl-4- nitroimidazoles” International Journal of Chemical Sciences 2009, 7(1), 204-210.
  • M. Ganesh,S. Uppatyay, R. Tivari, K. Kamalakannan,G. Rathinavel, S. Ganguly and T. Sivakumar, “Quantitation of Alfuzosin Hydrochloride in Pharmaceutical Formulations by RP-HPLC”, Pak. Jr. Pharm. Scs, 2009, 22(3), 263-266
  • M. Veerapandian, M. Marimuthu, P. Ilangovan, S. Ganguly, Kyu-Sik Yun, Sanghyo Kim, Jeongho An, “Analytical and biological standardization of quinazoline semicarbazones derivatives” Med. Chem. Res. DOI 10.1007/s00044-009-9191-y
  • Avinash Patil , Swastika Ganguly , Sanjay Surana , Sanjay Pekamwar ,  and Abhay Sangamwar, Docking Studies Of Novel 2-[5-Substituted-1-H Benzo   (D)Imidazole-2-Yl Sulfinyl] Methyl 3-Substituted Quinazoline-4(3H)Ones, International Journal of Pharm Tech Research, 1(4), 2009,   1227-1233.
  • Swastika Ganguly  and Naresh Panigrahi, Docking Studies Of Some Novel 1-{2-(Diarylmethoxy)Ethyl]-2-Methyl-5-Nitroimidazole(DAMNI)Analogs”,International Journal of ChemTech Research ,Oct-Dec 2009, Vol.1, No.4, 974-984.
  • Avinash Patil, Swastika Ganguly and Sanjay Surana, “Synthesis and antiulcer activity of novel 2-[5-substituted 1H-benzo(d) imidazole-2-yl sulfinyl) methyl -3-substituted quinazoline-4(3H)ones” Indian Journal of Het. Chem., Oct-Dec 2009, 19, 113-115.
  • Swastika Ganguly,S. Murugesan and Giovanni Maga, “Synthesis, Evaluation And Molecular Modeling Studies Of Some Novel Tetrahydroisoquinoilne Derivatives Targeted At The HIV-1 Reverse Transcriptase” Indian Journal of Het. Chem, April 2009, 18(4), 357-360.
  • S. Ganguly and V. Gopalakrishnan, 3D QSAR studies of DAMNI analogs as possible non nucleoside Reverse transcriptase Inhibitors, E Journal of Chemistry, 2008, 5(S2), 1103-1113.
  • Papiya Mitramazumder, Rana Datta, R.N. Majee and S. Ganguly, Synthesis and antimicrobial activity of some derivatives of aleuritic acid, Indian Journal of Heterocyclic Chemistry, July Sept 2008, 18, 73-76.
  • M. Ganesh, B. Thangabalan, Swastika Ganguly, T. Sivakumar, “Simple extractive colorimetric determination of oxaprozin by acid-dye complexation methods  in solid dosage form” E journal of chemistry, July 2008, 5(3), 593-597
  • Mani Ganesh, Mani Vasudevan, Kaliappan Kamalakannan, Arthanari Saravana Kumar1, Mari Vinoba , Swastika Ganguly , Thangavelu Sivakumar, “Anti-inflammatory and Analgesic Effects of Pongamia glabra Leaf Gall Extract” Pharmacologyonline, , 2008, 1,497-512.
  • M. Ganesh, B. Thangabalan, Rahul Patil, Dinesh Thakur, A.Saravana Kumar, M. Vinoba, Swastika Ganguly, T. Sivakumar, “Validated HPLC Method for Analysis of Oxaprozin in a Formulation Acta Chromatographica, 2008, 20 (2), 165–173
  • M. Ganesh, B. Thangabalan, Swastika Ganguly, T. Sivakumar, “Simple extractive colorimetric determination of oxaprozin by acid-dye complexation methods  in solid dosage form” E journal of chemistry, July 2008, 5(3),593-597.
  • Mani Ganesh, Mani Vasudevan, Kaliappan Kamalakannan, Arthanari Saravana Kumar1, Mari Vinoba , Swastika Ganguly , Thangavelu Sivakumar, “Anti-inflammatory and Analgesic Effects of Pongamia glabra Leaf Gall Extract” Pharmacologyonline, 2008, 1, 497-512.
  • S. Ganguly and V. Gopalakrishnan, 3D QSAR studies of DAMNI analogs as possible non nucleoside Reverse transcriptase Inhibitors, E Journal of Chemistry, 2008, 5(S2), 1103-1113.
  • Papiya Mitramazumder, Rana Datta, R.N. Majee and S. Ganguly, Synthesis and antimicrobial activity of some derivatives of aleuritic acid, Indian Journal of Heterocyclic Chemistry, July Sept, 2008, 18,73-76.
  • Ganguly S. and Razdan B.K., ‘Synthesis of Novel 2-Methylimidazole    Derivatives, Indian Journal of Heterocyclic Chemistry, July-Sept 2007, 17, 87-88.

 

National:

  • Swastika Ganguly, Shweta Sinha and Abhimanyu Dev, “Synthesis and antimicrobial activity of some new bisimidazole analogs Journal of Institution of Chemists, 2012, 84(4), 124-128
  • S. Ganguly, N. Panigrahi, S.N. Cremer and A. Dev, “Microwave Assisted Synthesis and Evaluation Of Some 1-{2-(hydroxyethyl]-2-Methyl-5-Nitroimidazole Analogs” Journal of Institution of Chemists, 2011, 83,65-71.
  • Baskar L, Papita Mitramazumder, D. Sasmal and Swastika Ganguly, “In-vitro      antihistaminic activity of some 1-substituted imidazoles- H2receptor antagonism”, Journal of Pharmaceutical Sciences and Research, 2011, 3(1), 961-965.
  • Swastika Ganguly, Pankaj kr. Gupta, Abhimanyu Dev, “Synthesis and antimicrobial evaluation of some 1-substituted 2-methyl-5-nitroimidazoles”, Pharmbit, Jan-Jun 2010, XXI(1),29-32.
  • S. Ganguly, K.J. Patel and R. Chandra, “Synthesis and Antimicrobial Evaluation of some 1-[5-(p-SubstitutedPhenyl)-2-Mercapto-1H-Imidazol-1-Yl]-3-(Aryl)Thioureas”, Journal of Institution of Chemists (India), 2010, 82(2), 52-58.
  • Swastika Ganguly and S. Murugesan, “Synthesis and in vitro Antimicrobial Activities of Novel Tetrahydroquinoline and Tetrahydroisoquinoline Analogues”, J.Ind. Chem Soc., 2010, 87,1-7.
  • Poonilavarasan Ilangovan, Swastika Ganguly and Vijay Pandi, “Design and Synthesis of Novel Quinazolinone derivatives as broad spectrum anticonvulsant and antimicrobial agents”, Journal of Pharmacy Research, 2010, 3(4), 703-706.
  • Ganguly S, Mishra R, “Comparative Molecular Similarity Indices Analysis of 1- (Naphthylalky1)-1H–imidazole Analogs with Antiepileptic Activity” Journal of Young Pharmacists, Oct-Dec, 2010, 2(4), 388-392.
  • S. Ganguly, P. MitraMazumder, D.Sasmal, G.M. Panpalia, S.Jha, S.G.Panpalia and R.Chandra, ‘Spirulina as a green remedy – An Overview’, Science and  Culture, 2009, 75(1-2), 12-17.
  • Avinash Patil, Swastika Ganguly and Sanjay Surana, “Synthesis and Antiulcer Activity of 2-[ 5-substituted 1-H-benzo(d)imidazole-2-yl sulfinyl methyl ]3-Phenyl Quinazoline-4(3H)one Derivatives” Asian Journal of Chemistry, 2009, 1(2), 1491-1494.
  • S. Ganguly, S. P. Bhatnagar and V. Kaushik, “Development of software for identification of indigenous drugs”, Pharmacognosy Research, 2009, 1(1), 35-37.
  • S. Ganguly, Vishwanathan K and R. Chandra, “Synthesis and Antibacterial activity of some N-substituted -3-(2-methyl-5-nitro-imidazol-1-yl)-propionamides”, Journal of Institution of Chemists (India), (2009), 81(2), 57-62.
  • S. Ganguly and N. Prasanthi, “3D-QSAR Studies of NAIMS Analogs as anti-HIV agents”, Journal of Young Pharmacists, 2009, 1(3), 251-258.
  • Swastika Ganguly and S.P. Bhatnagar, “Development of a Computerized Database for Identification of Indigenous Drugs”, Pharmacognosy Magazine, 2008, 4(14), 65-71.
  • S. Ganguly and S. Banerjee, “3D-QSAR Studies of Imidazole Derivatives as   Candida Albicans P450 – Demethylase Inhibitors” Asian Journal of       Chemistry, 2008, 20(6), 4595-4608.
  • M.Ganesh, K. Kamalakrishnan, Rahul Patil, Satish Upadhyay, Anand Srivastava, T.Sivakumar and Swastika Ganguly, “A validated UV Spectrophotometric method for the determination of letrozole in bulk and solid dosage form”, Rasayan Journal of Chemistry, 2008, 1(1),55-58.
  • M. Ganesh, B. Thangabalan, Dinesh Thakur, K. Srinivasan, Swastika Ganguly and T. Sivakumar, “UV Spectrophotometric Determination of Oxaprozin in   Pure and Pharmaceutical Formulation”, Asian Journal of Chemistry, 2008, 20(7),  5451-54.
  • S. Ganguly and S, Murugesan, “Docking studies of novel tetrahydroquinoline and tetrahydroisoquinoline analogues into the non-nucleoside inhibitor binding site of HIV-1 RT”,  Rasayan Journal of Chemistry, 2008, 1(2), 251-257.
  • Avinash Patil, Swastika Ganguly and Sanjay Surana, “A Systematic Review of Benzimidazole Derivatives as an antiulcer agent”, Rasayan Journal of Chemistry, 2008, 1(3), 447-460.
  • Swastika Ganguly, P. Partani and S. Samanta, “Solid Phase Organic Synthesis (SPOS) - An Overview”. Pharmbit, Jan-Jun 2008, Vol XVIII(1), 12-16.
  • Swastika Ganguly, Amresh Kumar and Ramesh Chandra, “Synthesis and antifungal evaluation of 1-substituted azoles”, Pharmbit, July-Dec.2008, XVIII(2), 105-107.
  • M. Ganesh, P. Sunitha, A. Saravanakumar, K. Srinivasan, M. Vinoba, S. Ganguly and T. Sivakumar, “ A validated RP=HPLC method for simultaneous estimation of acetaminophen and methacarbamol in tablets”, Asian Journal of Chemistry, 2008, 20(8), 6501-6504.
  • Sumit Mishra, Gurdeep Singh, Usha Jha and Swastika Ganguly, “Long term leaching studies on Coal combustion residues from Balco Captive Power Plant, Korba” Journal of Indian Chemical society, April 2008, 85,pp. 429- 433.
  • S.Ganguly and S. Banerjee, “Synthesis, Antifungal activity and Molecular Modeling Studies of Some Novel 1-Substituted 2-methylimidazole Analogs”, Journal of Indian Council of Chemists, 2007, 24(1), 178-181.
  • S. Ganguly and K. Somakala, “Synthesis and Screening of N-(Aryl)-2-(2-Methyl-4-Nitro-1H-Imidazol-1-yl-) Acetamides for Antibacterial Activity” Journal of Institution of Chemists (India), 2007, 79(6), 33-38.
  • S. Ganguly and S, Murugesan, “Molecular Dynamics – A versatile tool for Drug Design”, Pharmbit, Jan-Jun 2007, XV(1), 43-47.

 

Presentations:

  • Jacob K, S.; Ganguly, S. Molecular Docking Studies of Novel Pyrazole Analogs as Possible HIV-1-RT Inhibitors. In Proceedings of the 18th Int. Electron. Conf. Synth. Org. Chem., 1 - 30 November 2014; Sciforum Electronic Conference Series, Vol. 18, 2014 , b033; doi:10.3390/ecsoc-18-b033
  • Swastika Ganguly, Sony Jacob and S. Murugesan, Molecular Modelling studies, synthesis and evaluation of some (N,N-bis 3,5 dimethyl pyrazole-1-yl)methyl] aniline analogs as possible HIV-1 RT inhibitors, Proceedings of DST sponsored iInternational seminar on Recent Advances in Clinical Research with a special emphasis on BA/Be study organized by Bioequivalence Study Centre , Department of Pharmaceutical Technology, Jadavpur University, Kolkata-India held on 11th -15th September 2014.
  • Jinu Issac, Swastika Ganguly, Santanu Kaity and Animesh Ghosh, Enhancement of bioavailability of telmisartan by comilling with poly(vinyl alcohol), Proceedings of DST sponsored International seminar on Recent Advances in Clinical Research with a special emphasis on BA/Be study organized by Bioequivalence Study Centre , Department of Pharmaceutical Technology, Jadavpur University, Kolkata-India held on 11th -15th September 2014.
  • Biplab Debnath , Swastika Ganguly,In silico design of isatin analogs as possible anti HIV agents with broad spectrum chemotherpeutic properties, Proceedings of International Conference on Drugs for the Future: Infectious Diseases(DFID-2014) at NIPER, Hyderabad on 27th-28th March 2014,p 64.
  • Swastika Ganguly, Surabhi Mishra and Biplab Debnath, Molecular modelling studies of novel 1, 2-diarylimidazoles as possible nnrtis with broad spectrum properties, Proceedings of National Seminar on Challenges, Opportunities and futuristic trend in Pharmacy Education at IIT, BHU on 3rd-4th March,2014, PC-P1.
  • Sankrityayan Ira, Gupta Ankita, Swastika Ganguly, In silico design of 1,2-diarylimidazoles as possible antiHIV agents with broad spectrum chemotherapeutic properties, Proceedings of 2nd Pharm. Tech. IAPST International Conference on New Insights into Diseases and Recent Therapeutic Approaches , Jadavpur University, Kolkata-32, 2014, p-69.
  • Ashok P, Subhash Chander, S. Ganguly,Rafael-Balana Fouce and S. Murugesan,Synthesis and evaluation of beta carboline derivatives as antilesihmanial agents,Proceedings of 2nd UK –India MedChem Congress,organized by IICT, Hyderabad, 22-23 March 2013
  • Ashok P, Murugesan S and S. Ganguly, Design and comparative docking studies of novel 1-phenyl-2,3,4,9 tetrahydro-1H-pyrido{3,4-b]indole-3-carboxylic analogs as inhibitors of HIV-1-Reverse transcriptase, Proceedings of World Conference on HIV and AIDS 2012, pg 51.
  • Jinu Issac, Santanu Kaity, Swastika Ganguly and Animesh Ghosh,  Bioavailabilty enhancement of Glipizide by microwave induced solid dispersion”, Proceedings for DST sponsored International Seminar on Clinical Research  and Regulatory Affairs-Present scenario on 16th July 2012 held at Dr. K.P. Basu Memorial hall, Jadavpur University organized by Bioequivalence Centre, Dept. of Pharmaceutical; Technology, Jadavpur University, Kolkata-32
  • Ashok P, Kakumanu Kishore Babu,S. Murugesan and S. Ganguly, “ Design and docking studies of some novel 2-substituted Tetrahydro- β carbolines as Human Immunodeficiency Virus Type-1 Reverse Transcriptase Inhibitors” Proceedings for the 10th Annual Symposium of International Consortium on Antivirals(ICAV) , 2012, pg 56.
  • Baskar L, Papiya Mitramazumder, Dinakar Sasmal, Venkatesan Jayaprakash, Swastika Ganguly and Ashok K. Pattnaik, “Docking studies of some N-1 substituted imidazoles on M1, M2 and M3 receptors: An antidiarrheal efficacy”Proceedings of 63rd  Indian Pharmaceutical Congress, 2011, B30.
  • Swastika Ganguly and Debarun Chatterjee," Docking studies of 1,2 disubstituted imidazoles as possible antiHIV, antimycobacterial and antifungal agents," Proceedings of 63rd Indian Pharmaceutical Congress, 2011, B32.
  • Swastika Ganguly and Arpita Upadhyay," In silico design of 1,4-diarylimidazole -2-thione analogues for possible anticancer activity acting on EGFR receptor", Proceedings of 63rd India Pharmaceutical Congress, 2011, B35.
  • Patel Hardik S. and Swastika Ganguly, “Molecular modeling studies of 3-(4-chlorophenyl)-4-(1H imidazole-1-yl)-5-phenyl-4,5-dihydrp-1H pyrazole derivatives as possible HIV-1-RT inhibitors” Proceedings of 63rd  Indian Pharmaceutical Congress, 2011, B36.
  • Kakumanu Kishore babu, S. Murugesan and S. Ganguly, “ Design and Docking studies of some novel H1N1 neuraminidase inhibitors”, Proceedings of National Conference on Chemical Sciences in New Millennium , Pacific University, Udaipur, Rajasthan, 8th January 2012.
  • Swastika Ganguly and Shweta Sinha," Modelling studies of novel bisimidazoles as possible antiHIV and anti-mycobacterial agents", Proceedings of 3rd Indian Pharmaceutical Association Convention, 2011, 62.
  • Swastika Ganguly and B.S. Nagaraj, “In-silico design of 1,2-disubstituted imidazoles as possible antiHIV with broad spectrum chemotherapeutic agents” Proceedings of 62nd Indian Pharmaceutical Congress, 2010, B272.
  • R.Kuhu, T. Balaraju, A. Kesharwani, S. Ganguly and A. Sharon, “Targeting Drug Discovery by catalyzing 3D HIV Integrase modelProceedings of BIT’s 1st World Congress of Virus and Infections -2010 (WCVI-2010), page 462.
  • L.Baskar, P. Mitramazumder,D. Sasmal and Swastika Ganguly, “ An in vitro evaluation of the antimicrobial efficacy of some N-substituted imidazoles”Proceedings of Pharmacon 2010, Department of Pharmaceutical Sciences,      April9-10, 2010, pg 34.
  • S.M. Firdous, Swastika Ganguly, Raju Koneri, Anupam Kanti Bag, “Protective effect of Ipornea staphylina on carbon tetrachloride induced hepatotoxicity and Gentamicin induced nephrotoxicity in rats”, Proceedings of Pharmacon 2010, Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi ,April 9-10, 2010, pg 17.
  • I.Poonilavarasan, Swastika Ganguly, S.R. Trinath and A. Rajasekaran, “Synthesis and anticonvulsant activity of Quinazoline drivatives”, Proceedings of TexoPharma Virtus 09, 2009.
  • L. Baskar, Papiya Mitra Mazumder, D. Sasmal and S.Ganguly, “Antidiarrheal and  spasmolytic activities of some N-substituted 2-methylimidazoles”, Proceedings of  TexoPharma Virtus 09,organized by college of Pharmacy, Mother Theresa PG and Research Institute of Health Sciences, Pondicherry, 2009.
  • L. Baskar, Papiya Mitra Mazumder, D. Sasmal and S.Ganguly, “H2 receptor antagonism and antiulcer activity of some N-substituted 2-methylimidazoles”, Proceedings of 61st Indian Pharmaceutical Congress, 2009, 226.
  • Suresh Kumar K, Ganguly S, Clerq ED, Rajasekaran A, “Synthesis, antiviral and cytotoxic evaluation of non nucleoside-3-(benzylideneamino)-2-phenylquinazoline-4(3H)ones”, Proceedings of 61st Indian Pharmaceutical Congress, 2009, 226.
  • Vatsal V. Vithlani, S. Ganguly, N. Panigrahi and P. Mitramazumder, “Design, Synthesis and evaluation of some novel 1-[2-hydroxyethyl]-2-methyl-5-nitroimidazoles as antiHIV agents”, Proceedings of 61st Indian Pharmaceutical Congress, 2009, 274.
  • Poonilavarasan Ilangovan, Swastika Ganguly and Vijay Pandi, “Synthesis  and Pharmacological activities of  Quinazolinone derivatives”, Proceedings of 61st  Indian Pharmaceutical Congress, 2009, 287.
  • Pankaj K. Gupta, Swastika Ganguly and N. Panigrahi, “Binding Mode Analysis of Some Novel 1-(2-Diarylmethoxy)ethyl)-2-methyl-5-nitroimidazole analogs”, Proceedings of the 14th Annual national Convention of Association of Pharmaceutical Teachers of India,organized by Lachoo Memorial College of Sciences and Technology, Pharmacy Wing, 2009, SA55.
  • A. Rajasekaran, I.Poonilavarasan, D. Kalaiyarasi and Swastika Ganguly, “Synthesis, Characterization and Antimicrobial Evaluation of Quinazoline Schiff Bases”, Proceedings of National Level Seminar on Stereochemical Adventures in the synthesis of challenging drug molecules at , 2009, 21-22.
  • Papiya Mitra Mazumder, Swastika Ganguly, D. Sasmal and L. Baskar, “LD 50 Determination and Behavorial Studies of certain novel 1-substituted-2-methylimidazole derivatives: A blind screening ”, Proceedings of 60th Indian Pharmaceutical Congress, 2008, 372.
  • Amresh Kumar and Swastika Ganguly, “Synthesis and evaluation of some azole analogs as potential antifungal agents”, Proceedings of 60th Indian Pharmaceutical Congress, 2008, 245.
  • A.V. Patil, S. Ganguly and S.J. Surana, “Synthesis, Docking and in vivo antiulcer activity of novel 2-(1H-Benzo(D)imidazol-2-yl-sulfinyl)methyl 3-substituted quinazoline-4- (3H)-one derivatives”, Proceedings of 60th Indian Pharmaceutical Congress, 2008, 208.
  • Murugesan S. and Swastika Ganguly, “Docking Studies of Some Novel 1, 2, 3, 4- Tetrahydroisoquinoline analogs as HIV -1- non nucleosidal Reverse Transcriptase Inhibitors”, Proceedings of 60th Indian Pharmaceutical Congress, 2008, 197.
  • R. Kuhu, S. Ganguly and S. Murugesan, “Pharmacophoric Distance Mapping Study of Some Non Nucleosidal Reverse Transcriptase Inhibitors” , Proceedings of 60th Indian Pharmaceutical Congress, 2008, 195.
  • L. Baskar, Papiya Mitramazumder, D. Sasmal and Swastika Ganguly,” Behavorial studies of certain novel 1-substituted 2-methylimidazole derivatives: A blind screening” held in the APTI 13th Annual National Convention at SLT Institute of Pharmaceutical Sciences,Guru Ghasidas University, Bilaspur, from 3rd-4th October,2008.
  • Avinash Patil , Swastika Ganguly , Sanjay Surana , Sanjay Pekamwar, Abhay Sangamwar, Gastric H+ / K+ Atpase as drug target” presented in the International Conference on Drug Discovery and Nanotechnology held in the Department of Chemistry , Yesvant Mahavidyalaya, Nanded , Maharashtra from 27-29 January 2008.
  • V. Gopalakrishnan and Swastika Ganguly, “3DQSAR studies of novel 1-substituted 2-methyl-5-nitroimidazole derivatives as HIV-1 Non Nucleoside Reverse Transcriptase Inhibitors” Proceedings of 26th Annual Conference of Indian Council of Chemists, 2007, 263.
  • S. Murugesan and Swastika Ganguly, “Flexible docking study of some novel quinoline and isoquinoline analogs” Proceedings of 26th Annual Conference of Indian Council of Chemists, 2007 ,262.
  • Baskar, G. Nagalakshmi, Papiya Mitra Mazumder, D Sasmal, Swastika Ganguly, S. Murugesan, “Wound healing and an antimicrobial efficacy of Ixora cocinea Linn root extracts”, L. Proceedings of 59th Indian Pharmaceutical Congress, BHU, Varanasi, 20th – 23rd December, 2007.
  • Satish Upadhayay, Jagadeswaran M, Rishi Tiwari, Kamalakrishnan, S. Ganguly and Sivakumar T, “An u.v. spectrophotometric determination of letrozole in bulk and solid dosage form” presented in 59th Indian Pharmaceutical Congress, BHU, Varanasi, 20th to 24th December 2007.
  • Rahul Patil, Thangabalan B, Rajavel R, Dinesh Thakur, Ganesh M, S. Ganguly and Sivakumar T, “New validated RP-HPLC method for the estimation of Oxaprozonin bulk and solid dosage Form” presented in 59th Indian    Pharmaceutical Congress, BHU, Varanasi, 20th to 24th December 2007.
  • Ganesh M, Rahul Patil, Thangabalan B, Dinesh Thakur, S. Ganguly and Sivakumar T, “UV Spectrophotometric determination of Oxaprozin in pure and pharmaceutical formulation” presented in 59th Indian Pharmaceutical Congress, BHU, Varanasi, 20th to 24th December 2007.
  • A. Patil, S. Ganguly, S. Suranaand J. Hundiwale, “Synthesis of Benzimidazole derivatives as an antiulcer agents” presented in 59th Indian Pharmaceutical Congress, BHU, Varanasi, 20th to 24th December 2007.
  • S. Banerjee, S. Ganguly and R. Chandra, “Synthesis, antifungal activity and  Molecular Modeling studies of some novel 1-substituted 2-methylimidazole analogs”, presented in 59th Indian Pharmaceutical Congress, BHU, Varanasi, 20th to 24th December 2007.
  • L. Baskar, G. Nagalakshmi, Papiya MitraMazumder, D. Sasmal, Swastika Ganguly and S. Murugesan, “ A comparative invitro antimicrobial efficacy of certain 2-substituted oxazole derivatives: Synthesis and depiction” presented in APTI Annual National Convention held at University Institute of Pharmaceutical Sciences, Punjab University, Chandigarh from 25-27 October 2007.
  • Ganesh M, Aruna M, Jagdeswaran M, M. Vinoba, Kamalakannan, Swastika Ganguly and Sivakumar T, “Development and Validation of New RP-HPLC analytical techniques for Letrozole in Bulk and its Solid dosage” presented in the “Trends in Pharmaceutical Sciences -2007” Silver Jubilee Celebration of Department of Pharmacy held in  Annamalai University, Tamil Nadu on 30th-31st October 2007.

 

  Member of Professional Bodies
 

 ·         Life member of IPA, APTI, ISTE.

·         Executive member of IPA Jharkhand Branch of India.

·         Active Member of Review committee of UGC SAP Project.

·         Registered Pharmacist of Jharkhand State Registration Tribunal, Ranchi

 

  Current Sponsored Projects
 

 Title: In silico design, synthesis, and evaluation of  newer azoles as HIV-1-RT inhibitors, UGC, New Delhi (13.83 Lacs, Duration: 2013-2016)(As Principal Investigator)

 

 

Status: Ongoing. The project has just initiated .

 

 

Title: Study of physico-technological principles of preparation of new  magnetic nanostructures `for multifunctional biomedical applications, DST, New Delhi(9 lacs, Duration: 2012-2015)(As Co-Principal Investigator)

  Text and Reference Books
 

 Book Chapters: 02

 

  1. Swastika Ganguly, QSAR in Drug Design, Ed., B. K. Razdan, CBS Publishers, New Delhi, 2012 ,1st Edition,  pg 235-254.
  2. Swastika Ganguly, Molecular Modelling in Drug Design,Ed., B. K. Razdan, CBS Publishers, New Delhi, 2012 , 1st Edition, pg 256-282.

 

  Patent
 

Patents filed : Six

                                               

Serial

number

Ref. no.

Application Type

Application Number

Title/Remarks

1

ORDINARY APPLICATION

75/KOL/2012

THIAZOLIDINE-2,4-DIONE DERIVATIVES,THEIR SYNTHESIS AND USES

2.

ORDINARY APPLICATION

655/KOL/2013

NOVEL THIAZOLIDINE-DIONE ANALOGS AS AN ANTIMICROBIAL AGENTS

3.

ORDINARY APPLICATION

1226/KOL/2013

ISATIN(1H-INDOLE-2,3-DIONE)DERIVATIVES,THEIR SYNTHESIS AND USES

4.

ORDINARY APPLICATION

1323/KOL/2013

NOVEL BENZIMIDAZOLES AS ANTIMICROBIALS

5.

ORDINARY APPLICATION

1351/KOL/2014

NOVEL IMIDAZOLES AS ANTIMICROBIALS

6.

ORDINARY APPLICATION

830/KOL/2014

DELIVERY OF TELMISARTAN…..,

PREPARATION THEREOF

 

  Fellow
 

 Fellow of Institution of Chemists