Birla Institute of Technology, Mesra
Dr. Bapi Gorain
Assistant Professor, Pharmaceutical Sciences and Tech
Ph.D. 		Contact Address
Permanent Address Sonar Para, Ward No. 4, P.O. Jhalda, Purulia 723202, West Bengal
Local Address Q. No. CII/34, Outer Campus, BIT Mesra, Ranchi 835215, Jharkhand
Phone (Office) 9088585676
Phone Residence 9088585676
Email Id bapi.gorain@bitmesra.ac.in
Joined Institute on : 19-Oct-2021
  Work Experience
 
Teaching : 8 Years

Research : 10.5 Years

Individual: 18.5 Years
  Professional Background

Ph.D. in Pharmacy (2014) from Jadavpur University, India
Master of Pharmacy, Specialization: Pharmacology, (1st Class) (2004), from Jadavpur University, India
Bachelor of Pharmacy (1st Class with Honours) (2002) from Jadavpur University, India
  Research Areas
 

Improvement of efficacy and safety of therapeutic agents

  Award and Honours
 

Enlisted as World Top 2% Scientists for a single year (2020) by Stanford University based on standardized citation indicator.
STAR award (2014) for recognition of exemplary performance at work at Crest Premedia Solutions Private Limited.
Awarded Senior Research Fellowship from ICMR (Extramural Project) (2011-2014)
Senior Research Fellowship, Defense Research and Development Organization (DRDO), 2008 - 2010.
Junior Research Fellowship, University Grants Commission (UGC), 2002-2004.
  Publications
 

2024

Malhotra, S., Jain, N., Rathee, J., Kaul, S., Nagaich, U., Pandey, M., Gorain, B. and Gupta, G., 2024. Nanoneuroscience: Cutting-edge Approach for Disease Management. Recent patents on nanotechnology, 18(2), pp.256-271.

2023

  • Karmakar, V., Gorain, B., 2023. Potential molecular pathways of angiotensin receptor blockers in the brain toward cognitive improvement in dementia. Drug Discovery Today, 29(1):103850. 
  • Hsin, Y.K., Thangarajoo, T., Choudhury, H., Pandey, M., Meng, L.W. and Gorain, B., 2023. Stimuli-responsive in situ spray gel of miconazole nitrate for vaginal candidiasis. Journal of Pharmaceutical Sciences, 112(2):562-572 
  • Pandey, M., Karmakar, V., Majie, A., Dwivedi, M., Md, S. and Gorain, B., 2023. The SH-SY5Y cell line: a valuable tool for Parkinson’s disease drug discovery. Expert Opinion on Drug Discovery, pp.1-14.
  • Rohtagi, P., Garg, U., Jain, N., Pandey, M., Amin, M.C.I.M., Gorain, B. and Kumar, P., 2023. Chitosan and hyaluronic acid-based nanocarriers for advanced cancer therapy and intervention. Biomaterials advances, p.213733. 
  • Gour, A., Dogra, A., Verma, M.K., Bhardwaj, M., Kour, D., Jamwal, A., Gorain, B., Kumar, M., Vij, B., Kumar, A., Nandi U., 2023. Ayurveda-based phytochemical composition attenuates lung inflammation and precipitates pharmacokinetic interaction with favipiravir: an in vivo investigation using disease-state of acute lung injury. Natural Product Research, 37(22):3758-3765. 
  • Jacob, S., Nair, A.B., Boddu, S.H.S., Abuhijjleh, R.K., Selvaraju, K., Babu, T., Gorain, B., Shah, J., and Morsy M.A., 2023. The emerging role of lipid nanosystems and nanomicelles in liver diseases. European Review for Medical and Pharmacological Sciences, 27(18):8651-8680.
  • Singh, G., Rathee, J., Jain, N., Nagaich, U., Kaul, S., Pandey, M. and Gorain, B., 2023. Nano-approaches and Recent Advancements in Strategies to Combat Challenges Associated with Thyroid Cancer Therapies. Recent Patents on Nanotechnology.
  • Thangarajoo, T., Hsin, Y.K., Pandey, M., Choudhury, H., Meng, L.W., Md, S., Akhter, M.H. and Gorain, B., 2023. A stimuli-responsive in situ spray hydrogel co-loaded with naringenin and gentamicin for chronic wounds. Open Chemistry, 21(1), p.20220357. 
  • Roy, P., Chakraborty, S., Pandey, N., Kumari, N., Chougule, S., Chatterjee, A., Chatterjee, K., Mandal, P., Gorain, B., Dhotre, A.V., Bansal, A.K., and Ghosh A., 2023. Study on Sulfamethoxazole–Piperazine Salt: A Mechanistic Insight into Simultaneous Improvement of Physicochemical Properties. Molecular Pharmaceutics, 20(10):5226-5239. 
  • Gorain, B., Karmakar, V., Sarkar, B., Dwivedi, M., Leong, J.T.L., Toh, J.H., Seah, E., Ling, K.Y., Chen, K.Y., Choudhury, H., and Pandey M., 2023. Biomacromolecule-based nanocarrier strategies to deliver plant-derived bioactive components for cancer treatment: A recent review. International Journal of Biological Macromolecules, 253(Pt 1):126623. 
  • Pandey, M., Ting, J.S.S., Gorain, B., Jain, N. and Mayuren, J., 2023. Miniaturized Polymeric Systems for the Intravaginal Gene Therapies: Recent update on Unconventional Delivery. Current Pharmaceutical Design, 29(40):3254-3262.
  • Choudhury, H., Pandey, M., Saravanan, V., Mun, A.T.Y., Bhattamisra, S.K., Parikh, A., Garg, S. and Gorain, B., 2023. Recent progress of targeted nanocarriers in diagnostic, therapeutic, and theranostic applications in colorectal cancer. Biomaterials Advances, p.213556.
  • Pandey, M., Lang, H.X., Loh, J.S., Ling, M.C.Y., Long, F.T.H., Mayuren, J., Candasamy, M., Gorain, B., Jain, N., Gupta, G. and Dua, K., 2023. Dendrimer platform against prostate cancer: Recent update on new horizon of treatment. Journal of Drug Delivery Science and Technology, p.104589. 

2022

  • Nair, A.B., Gorain, B., Pandey, M., Jacob, S., Shinu, P., Aldhubiab, B., Almuqbil, R.M., Elsewedy, H.S. and Morsy, M.A., 2022. Tocotrienol in the Treatment of Topical Wounds: Recent Updates. Pharmaceutics, 14(11), p.2479. 
  • Gour, A., Dogra, A., Verma, M.K., Bhardwaj, M., Kour, D., Jamwal, A., Gorain, B., Kumar, M., Vij, B., Kumar, A. and Nandi, U., 2022. Ayurveda-based phytochemical composition attenuates lung inflammation and precipitates pharmacokinetic interaction with favipiravir: an in vivo investigation using disease-state of acute lung injury. Natural Product Research, pp.1-8. 
  • Gadhave, D., Khot, S., Tupe, S., Shinde, M., Tagalpallewar, A., Gorain, B. and Kokare, C., 2022. Nose-to-brain delivery of octreotide acetate in situ gel for pituitary adenoma: Pharmacological and in vitro cytotoxicity studies. International Journal of Pharmaceutics, 629, p.122372.
  • Jain, N., Pandey, M., Sharma, P., Gupta, G., Gorain, B. and Dua, K., 2022. Recent developments in plant?derived edible nanoparticles as therapeutic nanomedicines. Journal of Food Biochemistry, p.e14479.
  • Choudhury, H., Pandey, M., Mohgan, R., Jack, J.J.S., David, R.N., Yi, N.W., Liang, C.T., Ting, S., Kesharwani, P. and Gorain, B., 2022. Dendrimer-based delivery of macromolecules for the treatment of brain tumor. Biomaterials Advances, p.213118. 
  • Sengupta, P., Choudhury, H., Dutta, S., Jacob, S., Kesharwani, P. and Gorain, B., Current Strategies in Breast Cancer Therapy: Role of Epigenetics and Nanomedicine. Particle & Particle Systems Characterization, p.2100276.
  • Md, S., Alhakamy, N.A., Sharma, P., Ansari, M.S. and Gorain, B., 2022. Nanocarrier-based co-delivery approaches of chemotherapeutics with natural P-glycoprotein inhibitors in the improvement of multidrug resistance cancer therapy. Journal of Drug Targeting, pp.1-18. 
  • Md, S., Abdullah, S., Alhakamy, N.A., Shaik, R.A., Ansari, A.R., Riadi, Y., Ahmad, J., Ali, R., Gorain, B. and Karim, S., 2022. Sustained-release ginseng/sodium alginate nano hydrogel formulation, characterization, and in vivo assessment to facilitate wound healing. Journal of Drug Delivery Science and Technology, 74, p.103565. 
  • Pandey, M., Jain, N., Kanoujia, J., Hussain, Z. and Gorain, B., 2022. Advances and Challenges in Intranasal Delivery of Antipsychotic Agents Targeting the Central Nervous System. Frontiers in pharmacology, p.904. 
  • Pandey, M., Choudhury, H., Vijayagomaran, P.A., Lian, P.N.P., Ning, T.J., Wai, N.Z., Xian-Zhuang, N., Le Er, C., Rahmah, N.S.N., Kamaruzzaman, N.D.B., Mayuren, J., Mayuren, C., Gorain, B., Chawla, P.A., Mohd Amin, M.C.I., 2022. Recent update on Bacteria as a delivery carrier in cancer therapy: from evil to allies. Pharmaceutical research, pp.1-20. 
  • Pandey, M., Choudhury, H., Ying, J.N.S., Ling, J.F.S., Ting, J., Ting, J.S.S., Zhia Hwen, I.K., Suen, H.W., Samsul Kamar, H.S., Gorain, B. and Jain, N., 2022. Mucoadhesive Nanocarriers as a Promising Strategy to Enhance Intracellular Delivery against Oral Cavity Carcinoma. Pharmaceutics, 14(4), p.795. 
  • Bandaru, R., Rout, S.R., Kamble, O.S., Samal, S.K., Gorain, B., Sahebkar, A., Ahmed, F.J., Kesharwani, P. and Dandela, R., 2022. Clinical progress of therapeutics and vaccines: Rising hope against COVID-19 treatment. Process Biochemistry, 118, pp.154-170. 
  • Gorain, B., Pandey, M., Leng, N.H., Yan, C.W., Nie, K.W., Kaur, S.J., Marshall, V., Sisinthy, S.P., Panneerselvam, J., Molugulu, N., Kesharwani, P., Choudhury, H. 2022. Advanced drug delivery systems containing herbal components for wound healing. International Journal of Pharmaceutics, p.121617.
  • Verma, R.K., Pandey, M., Chawla, P., Choudhury, H., Mayuren, J., Bhattamisra, S.K., Gorain, B., Raja, M.A.G., Amjad, M.W. and Rahman, S.O., 2022. An insight into the role of Artificial Intelligence in the early diagnosis of Alzheimer’s disease. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders). 
  • Stephen, S., Gorain, B., Choudhury, H. and Chatterjee, B., 2022. Exploring the role of mesoporous silica nanoparticle in the development of novel drug delivery systems. Drug delivery and translational research, 12(1):pp.105-23. 

2021

  • Gorain, B., Al-Dhubiab, B.E., Nair, A., Kesharwani, P., Pandey, M. and Choudhury, H., 2021. Multivesicular liposome: A lipid-based drug delivery system for efficient drug delivery. Current Pharmaceutical Design, 27(43), pp.4404-4415.
  • Jeckson, T.A., Neo, Y.P., Sisinthy, S.P., Foo, J.B., Choudhury, H. and Gorain, B.*, 2021. Formulation and characterisation of deferoxamine nanofiber as potential wound dressing for the treatment of diabetic foot ulcer. Journal of Drug Delivery Science and Technology, 66, p.102751.
  • Gorain, B., Al-Dhubiab, B.E., Nair, A., Kesharwani, P., Pandey, M. and Choudhury, H., 2021. Multivesicular Liposome: A Lipid-based Drug Delivery System for Efficient Drug Delivery. Current Pharmaceutical Design, 27(43), pp.4404-4415.
  • Nair, A.B., Al-Dhubiab, B.E., Shah, J., Gorain, B., Jacob, S., Attimarad, M., Sreeharsha, N., Venugopala, K.N. and Morsy, M.A., 2021. Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box–Behnken Design and In Vitro Evaluation. Pharmaceutics, 13(10), p.1692.
  • Alhakamy, N.A., Md, S., Alam, M.S., Shaik, R.A., Ahmad, J., Ahmad, A., Kutbi, H.I., Noor, A.O., Bagalagel, A., Bannan, D.F. and Gorain, B., 2021. Development, Optimization, and Evaluation of Luliconazole Nanoemulgel for the Treatment of Fungal Infection. Journal of Chemistry, 2021.
  • Jeckson, T.A., Neo, Y.P., Sisinthy, S.P. and Gorain, B., 2021. Delivery of therapeutics from layer-by-layer electrospun nanofiber matrix for wound healing: An update. Journal of Pharmaceutical Sciences, 110(2), pp.635-653.
  • Dalal, R., Shah, J., Gorain, B., Choudhury, H., Jacob, S., Mehta, T.A., Shah, H. and Nair, A.B., 2021. Development and Optimization of Asenapine Sublingual Film Using QbD Approach. AAPS PharmSciTech, 22(7), pp.1-20.
  • Gadhave, D., Tupe, S., Tagalpallewar, A., Gorain, B., Choudhury, H. and Kokare, C., 2021. Nose-to-brain delivery of amisulpride-loaded lipid-based poloxamer-gellan gum nanoemulgel: In vitro and in vivo pharmacological studies. International Journal of Pharmaceutics, 607, p.121050.
  • Patnaik, S., Gorain, B., Padhi, S., Choudhury, H., Gabr, G.A., Md, S., Mishra, D.K. and Kesharwani, P., 2021. Recent update of toxicity aspects of nanoparticulate systems for drug delivery. European Journal of Pharmaceutics and Biopharmaceutics, 161, pp.100-119.
  • Wong, Y.L., Pandey, M., Choudhury, H., Lim, W.M., Bhattamisra, S.K. and Gorain, B., 2021. Development of In-Situ Spray for Local Delivery of Antibacterial Drug for Hidradenitis Suppurativa: Investigation of Alternative Formulation. Polymers, 13(16), p.2770.
  • Dutta, S., Gorain, B., Choudhury, H., Roychoudhury, S. and Sengupta, P., 2021. Environmental and occupational exposure of metals and female reproductive health. Environmental Science and Pollution Research, pp.1-26.
  • Singh, S., Numan, A., Somaily, H.H., Gorain, B., Ranjan, S., Rilla, K., Siddique, H.R. and Kesharwani, P., 2021. Nano-enabled strategies to combat methicillin-resistant Staphylococcus aureus. Materials Science and Engineering: C, p.112384.
  • Chin, L.Y., Tan, J.Y.P., Choudhury, H., Pandey, M., Sisinthy, S.P. and Gorain, B., 2021. Development and optimization of chitosan coated nanoemulgel of telmisartan for intranasal delivery: A comparative study. Journal of Drug Delivery Science and Technology, 62, p.102341.
  • Pandey, M., Choudhury, H., Bhattamisra, S.K., Gorain, B., Su, J.S.T., Tan, C.L., Chin, W.Y. and Yip, K.Y., 2021. Potential of Stimuli-Responsive In Situ Gel System for Sustained Ocular Drug Delivery: Recent Progress and Contemporary Research. Polymers, 13(8), p.1340.
  • Jacob, S., Nair, A.B., Boddu, S.H., Gorain, B., Sreeharsha, N. and Shah, J., 2021. An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems. Pharmaceutics, 13(8), p.1206.
  • Singh, A., Mallika, T.N., Gorain, B., Yadav, A.K., Tiwari, S., Flora, S.J.S., Shukla, R. and Kesharwani, P., 2021. Quantum dot: Heralding a brighter future in neurodegenerative disorders. Journal of Drug Delivery Science and Technology, p.102700.
  • Pandey, M., Choudhury, H., Gorain, B., Tiong, S.Q., Wong, G.Y.S., Chan, K.X., They, X. and Chieu, W.S., 2021. Site-Specific Vesicular Drug Delivery System for Skin Cancer: A Novel Approach for Targeting. Gels, 7(4), p.218.
  • Shirbhate, E., Pandey, J., Patel, V.K., Kamal, M., Jawaid, T., Gorain, B., Kesharwani, P. and Rajak, H., 2021. Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention. Pharmacological Reports, pp.1-12.
  • Verma, R.K., Pandey, M., Chawla, P., Choudhury, H., Mayuren, J., Bhattamisra, S.K., Gorain, B., Raja, M.A.G., Amjad, M.W. and Rahman, O., 2021. An insight into the role of Artificial Intelligence in the early diagnosis of Alzheimer's disease. CNS & Neurological Disorders Drug Targets.
  • Shah, R., Soni, T., Shah, U., Suhagia, B.N., Patel, M.N., Patel, T., Gabr, G.A., Gorain, B. and Kesharwani, P., 2021. Formulation development and characterization of lumefantrine nanosuspension for enhanced antimalarial activity. Journal of Biomaterials Science, Polymer Edition, 32(7), pp.833-857.
  • Dubey, S.K., Pradhan, R., Hejmady, S., Singhvi, G., Choudhury, H., Gorain, B. and Kesharwani, P., 2021. Emerging innovations in nano-enabled therapy against age-related macular degeneration: A paradigm shift. International Journal of Pharmaceutics, 600, p.120499.
  • Chaudhary, S., Nair, A.B., Shah, J., Gorain, B., Jacob, S., Shah, H. and Patel, V., 2021. Enhanced Solubility and Bioavailability of Dolutegravir by Solid Dispersion Method: In Vitro and In Vivo Evaluation—a Potential Approach for HIV Therapy. AAPS PharmSciTech, 22(3), pp.1-12.
  • Kumbhar, S.A., Kokare, C.R., Shrivastava, B., Gorain, B. and Choudhury, H., 2021. Antipsychotic potential and safety profile of TPGS-based mucoadhesive aripiprazole nanoemulsion: Development and optimization for nose-to-brain delivery. Journal of pharmaceutical sciences, 110(4), pp.1761-1778.
  • Gour, A., Manhas, D., Bag, S., Gorain, B. and Nandi, U., 2021. Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS?CoV?2. Phytotherapy Research.
  • Stephen, S., Gorain, B., Choudhury, H. and Chatterjee, B., 2021. Exploring the role of mesoporous silica nanoparticle in the development of novel drug delivery systems. Drug delivery and translational research, pp.1-19.
  • Bhanderi, M., Shah, J., Gorain, B., Nair, A.B., Jacob, S., Asdaq, S.M.B., Fattepur, S., Alamri, A.S., Alsanie, W.F., Alhomrani, M. and Nagaraja, S., 2021. Optimized Rivastigmine Nanoparticles Coated with Eudragit for Intranasal Application to Brain Delivery: Evaluation and Nasal Ciliotoxicity Studies. Materials, 14(21), p.6291.
  • Pandey, M., Choudhury, H., Chetty Annan, N., Bhattamisra, S.K., Gorain, B. and Mohd Amin, M.C.I., 2021. Budesonide-Loaded Pectin/Polyacrylamide Hydrogel for Sustained Delivery: Fabrication, Characterization and In Vitro Release Kinetics. Molecules, 26(9), p.2704.
  • Elbehairi, S.E.I., Alfaifi, M.Y., Shati, A.A., Fahmy, U.A., Gorain, B. and Md, S., 2021. Encapsulation of Ellagic Acid in Di-Block Copolymeric Micelle for Non-Small Cell Lung Cancer Therapy. Science of Advanced Materials, 13(1), pp.66-72.
  • Yeo, E., Chieng, C.J.Y., Choudhury, H., Pandey, M. and Gorain, B., 2021. Tocotrienols-rich naringenin nanoemulgel for the management of diabetic wound: Fabrication, characterization and comparative in vitro evaluations. Current Research in Pharmacology and Drug Discovery, 2, p.100019.
  • Pandey, M., Choudhury, H., Abdul-Aziz, A., Bhattamisra, S.K., Gorain, B., Carine, T., Wee Toong, T., Yi, N.J. and Win Yi, L., 2021. Promising drug delivery approaches to treat microbial infections in the vagina: a recent update. Polymers, 13(1), p.26.
  • Pandey, M., Choudhury, H., Abdul-Aziz, A., Bhattamisra, S.K., Gorain, B., Su, J.S.T., Tan, C.L., Chin, W.Y. and Yip, K.Y., 2021. Advancement on sustained antiviral ocular drug delivery for herpes simplex virus keratitis: Recent update on potential investigation. Pharmaceutics, 13(1), p.1.

2020

  • Akrawi SH, Gorain B, Nair AB, Choudhury H, Pandey M, Shah JN, Venugopala KN. 2020. Development and optimization of naringenin-loaded chitosan-coated nanoemulsion for topical therapy in wound healing. Pharmaceutics. 2020, 12(9):893.
  • Tan, Z.M., Lai, G.P., Pandey, M., Srichana, T., Pichika, M.R., Gorain, B., Bhattamishra, S.K. and Choudhury, H., 2020. Novel approaches for the treatment of pulmonary tuberculosis. Pharmaceutics, 12(12), p.1196.
  • Cheng, S.N., Tan, Z.G., Pandey, M., Srichana, T., Pichika, M.R., Gorain, B. and Choudhury, H., 2020. A critical review on emerging trends in dry powder inhaler formulation for the treatment of pulmonary aspergillosis. Pharmaceutics, 12(12), p.1161.
  • Pandey, M., Choudhury, H., Verma, R.K., Chawla, V., Bhattamisra, S.K., Gorain, B., Raja, M.A. and Amjad, M.W., 2020. Nanoparticles based intranasal delivery of drug to treat Alzheimer’s disease: a recent update. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders), 19(9), pp.648-662.
  • Hejmady, S., Pradhan, R., Alexander, A., Agrawal, M., Singhvi, G., Gorain, B., Tiwari, S., Kesharwani, P. and Dubey, S.K., 2020. Recent advances in targeted nanomedicine as promising antitumor therapeutics. Drug discovery today.
  • Gorain, B., Choudhury, H., Nair, A.B., Dubey, S.K. and Kesharwani, P., 2020. Theranostic application of nanoemulsions in chemotherapy. Drug discovery today, 25(7), pp.1174-1188.
  • Choudhury H, Pandey M, Wen LP, Cien LK, Xin H, Yee AN, Lee NJ, Gorain B, Amin MC, Pichika MR. Folic acid conjugated nanocarriers for efficient targetability and promising anticancer efficacy for treatment of breast cancer: A review of recent updates. Current Pharmaceutical Design. 2020. 
  • Gorain B, Choudhury H, Nair AB, Dubey SK, Kesharwani P. Theranostic application of nanoemulsion in chemotherapy. Drug Discovery Today. 2020. 
  • Singh PK, Gorain B, Choudhury H, Singh SK, Whadwa P, Sahu S, Gulati M, Kesharwani P. Macrophage targeted amphotericin B nanodelivery systems against visceral leishmaniasis. Materials Science and Engineering: B. 2020;258:114571. 
  • Kumbhar SA, Kokare CR, Shrivastava B, Gorain B. Screening of nanoemulsion components for asenapine maleate using validated RP-HPLC method. Annales Pharmaceutiques Françaises 2020: 78(5): 379-385.
  • Kumbhar, S.A., Kokare, C.R., Shrivastava, B., Gorain, B. and Choudhury, H., 2020. Preparation, characterization, and optimization of asenapine maleate mucoadhesive nanoemulsion using Box-Behnken design: In vitro and in vivo studies for brain targeting. International Journal of Pharmaceutics, 586, p.119499. 
  • Gorain, B., Choudhury, H., Molugulu, N., Athawale, R.B. and Kesharwani, P., 2020. Fighting strategies against the novel coronavirus pandemic: impact on global economy. Frontiers in Public Health, 8.
  • Nair, A.B., Gandhi, D., Patel, S.S., Morsy, M.A., Gorain, B., Attimarad, M. and Shah, J.N., 2020. Development of HPLC Method for Quantification of Sinigrin from Raphanus sativus Roots and Evaluation of Its Anticancer Potential. Molecules, 25(21), p.4947.
  • Hussain Z, Pandey M, Choudhury H, Ying PC, Xian TM, Kaur T, Jia GW, Gorain B. Hyaluronic acid functionalized nanoparticles for simultaneous delivery of curcumin and resveratrol for management of chronic diabetic wounds: Fabrication, characterization, stability and in vitro release kinetics. Journal of Drug Delivery Science and Technology. 2020:101747. 
  • Choudhury H, Pandey M, Lim YQ, Low CY, Lee CT, Marilyn TC, Loh HS, Lim YP, Lee CF, Bhattamishra SK, Kesharwani P. Silver nanoparticles: Advanced and promising technology in diabetic wound therapy. Materials Science and Engineering: C. 2020:110925. 
  • Pandey M, Choudhury H, Fern JL, Kee AT, Kou J, Jing JL, Her HC, Yong HS, Ming HC, Bhattamisra SK, Gorain B. 3D printing for oral drug delivery: a new tool to customize drug delivery. Drug Delivery and Translational Research. 2020:1-6. 
  • Gorain B, Rajeswary DC, Pandey M, Kesharwani P, Kumbhar SA, Choudhury H. Nose to Brain Delivery of Nanocarriers Towards Attenuation of Demented Condition. Current Pharmaceutical Design. 2020. 
  • Verma LT, Singh N, Gorain B, Choudhury H, Tambuwala MM, Kesharwani P, Shukla R. Recent advances in self-assembled nanoparticles for drug delivery. Current Drug Delivery. 2020. 
  • Choudhury H, Maheshwari R, Pandey M, Tekade M, Gorain B, Tekade RK. Advanced nanoscale carrier-based approaches to overcome biopharmaceutical issues associated with anticancer drug ‘Etoposide’. Materials Science and Engineering: C. 2020: 106, 110275. 
  • Aldawsari HM, Gorain B, Alhakamy NA, Md S. Role of therapeutic agents on repolarisation of tumour-associated macrophage to halt lung cancer progression. Journal of drug targeting. 2020:28 (2), 166-175. 

2019

  • Choudhury H, Zakaria NF, Tilang PA, Tzeyung AS, Pandey M, Chatterjee B, Alhakamy NA, Bhattamishra SK, Kesharwani P, Gorain B, Md S. Formulation development and evaluation of rotigotine mucoadhesive nanoemulsion for intranasal delivery. Journal of Drug Delivery Science and Technology. 2019;54:101301. 
  • Choudhury H, Chellappan DK, Sengupta P, Pandey M, Gorain B. Adenosine receptors in modulation of central nervous system disorders. Current Pharmaceutical Design. 2019, 25, 1-20. 
  • Bapat RA, Dharmadhikari S, Chaubal TV, Amin MC, Bapat P, Gorain B, Choudhury H, Vincent C, Kesharwani P. The potential of dendrimer in delivery of therapeutics for dentistry. Heliyon. 2019;5(10):e02544.
  • Gorain B, Choudhury H, Yee GS, Bhattamisra SK. Adenosine receptors as novel targets for the treatment of various cancers. Current Pharmaceutical Design. 2019, 25, 1-14. 
  • Chatterjee B, Gorain B, Mohananaidu K, Sengupta P, Mandal UK, Choudhury H. Targeted drug delivery to the brain via intranasal nanoemulsion: available proof of concept and existing challenges. International Journal of Pharmaceutics. 2019; 565: 258-268. 
  • Choudhury H, Gorain B, Pandey M, Kaur R, Kesharwani P. Strategizing biodegradable polymeric nanoparticles to cross the biological barriers for cancer targeting. International Journal of Pharmaceutics. 2019; 565: 509-522. 
  • Choudhury H, Pandey M, Yin TH, Kaur T, Jia GW, Tan SL, Weijie H, Yang EK, Keat CG, Bhattamishra SK, Kesharwani P, Md S, Molugulu N, Pichika MR, Gorain B*. Rising horizon in circumventing multidrug resistance in chemotherapy with nanotechnology. Materials Science and Engineering: C. 2019; 101: 596-613. 
  • Kesharwani P, Choudhury H, Meher JG, Pandey M, Gorain B. Dendrimer-entrapped gold nanoparticles as promising nanocarriers for anticancer therapeutics and imaging. Progress in Materials Science. 2019; 103:484-508. 
  • Gadhave D, Gorain B, Tagalpallewar A, Kokare C. Intranasal teriflunomide microemulsion: An improved chemotherapeutic approach in glioblastoma. Journal of Drug Delivery Science and Technology. 2019; 51: 276-289. 
  • Zeeshan F, Madheswaran T, Pandey M, Gorain B. Three-dimensional (3-D) printing technology exploited for the fabrication of drug delivery systems. Current pharmaceutical design. 2018; 24(42): 5019-5028. 
  • Tripathi PK, Gorain B, Choudhury H, Srivastava A, Kesharwani P. Dendrimer entrapped microsponge gel of dithranol for effective topical treatment. Heliyon. 2019;5(3):e01343.
  • Bhattamisra SK, Siang TC, Rong CY, Annan NC, Sean EH, Xi LW, Lyn OS, Shan LH, Choudhury H, Pandey M, Gorain B. Type-3c Diabetes Mellitus, Diabetes of Exocrine Pancreas-An Update. Current diabetes reviews. 2019; 15(5):382-394.
  • Bapat RA, Joshi CP, Bapat P, Chaubal TV, Pandurangappa R, Jnanendrappa N, Gorain B, Khurana S, Kesharwani P. The use of nanoparticles as biomaterials in dentistry. Drug discovery today. 2019; 24(1): 85-98. 

2018

  • Gorain B, Choudhury H, Pandey M, Kesharwani P. Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy. Materials Science & Engineering C. 2018; 91:868-880. 
  • Gorain B, Choudhury H, Pandey M, Kesharwani P, Abeer MM, Tekade RK, Hussain Z. Carbon nanotube scaffolds as emerging nanoplatform for myocardial tissue regeneration: A review of recent developments and therapeutic implications. Biomedicine & Pharmacotherapy 2018;104:496-508. 
  • Pandey M, Choudhury H, Yeun OC, Yin HM, Lynn TW, Tine CL, Wi NS, Yen KC, Phing CS, Kesharwani P, Bhattamisra SK, Gorain B. Perspectives of nanoemulsion strategies in the improvement of oral, parenteral and transdermal chemotherapy. Current Pharmaceutical Biotechnology. 2018;19(4):276-92. 
  • Kumar RV, Sriramaneni R, Pandey M, Chaudhury H, Gorain B, Gupta G. Current updates on pharmacological roles of Glucagon-Like Peptide 1 (GLP-1) in obesity. Panminerva Medica. 2018; 60(4):224-225. 
  • Choudhury H, Pandey M, Chin PX, Phang YL, Cheah JY, Ooi SC, Mak KK, Pichika MR, Kesharwani P, Hussain Z, Gorain B. Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends. Drug Delivery and Translational Research. 2018:1-9. 
  • Bapat RA, Chaubal TV, Joshi CP, Bapat PR, Choudhury H, Pandey M, Gorain B, Kesharwani P. An overview of application of silver nanoparticles for biomaterials in dentistry. Materials Science and Engineering: C. 2018; 91:881-898. 
  • Pandey M, Choudhury H, Yi CX, Mun CW, Ping GK, Rou GX, Singh BJ, Jhee AN, Chin LK, Kesharwani P, Gorain B. Recent Updates on Novel Approaches in Insulin Drug Delivery: A Review of Challenges and Pharmaceutical Implications. Current Drug Targets. 2018; 19(15):1782-1800. 
  • Pandey M, Choudhury H, Gunasegaran T, Nathan SS, Shadab Md, Gorain B, Tripathy M, Hussain Z. Hyaluronic Acid Modified Betamethasone Encapsulated Polymeric Nanoparticles: Fabrication, Characterization, in Vitro Release Kinetics and Dermal Targeting. Drug Delivery and Translational Research. 2018:1-14. 
  • Choudhury H, Pandey M, Hua CK, Mun CS, Jing JK, Kong L, Ern LY, Ashraf NA, Kit SW, Yee TS, Pichika MR, Gorain B, Kesharwani P. An update on natural compounds in the remedy of diabetes mellitus: A systematic review. Journal of Traditional and Complementary Medicine. 2018;8(3): 361-376. 
  • Kesharwani P, Gorain B, Low SY, Tan SA, Ling EC, Lim YK, Chin CM, Lee PY, Lee CM, Ooi CH, Choudhury H. Nanotechnology based approaches for anti-diabetic drugs delivery. Diabetes Research and Clinical Practice. 2018;136:52-77. 

2017

  • Choudhury H, Gorain B, Tekade RK, Pandey M, Karmakar S, Pal TK. Safety against nephrotoxicity in paclitaxel treatment: Oral nanocarrier as an effective tool in preclinical evaluation with marked in vivo antitumor activity. Regulatory Toxicology and Pharmacology. 2017;91:179-89. 
  • Choudhury H, Gorain B, Pandey M, Kumbhar SA, Tekade RK, Iyer AK, Kesharwani P. Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy. International journal of pharmaceutics. 2017;529(1-2):506-22. 
  • Choudhury H, Gorain B, Pandey M, Chatterjee LA, Sengupta P, Das A, Molugulu N, Kesharwani P. Recent update on nanoemulgel as topical drug delivery system. Journal of pharmaceutical sciences. 2017;106(7):1736-51. 
  • Gorain B, Tekade M, Kesharwani P, Iyer AK, Kalia K, Tekade RK. The use of nanoscaffolds and dendrimers in tissue engineering. Drug discovery today. 2017;22(4):652-64. 
  • Choudhury H, Gorain B, Chatterjee B, K Mandal U, Sengupta P, K Tekade R. Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route. Current pharmaceutical design. 2017;23(17):2504-31. 
  • Sengupta P, Chatterjee B, Mandal UK, Gorain B, Pal TK. Development and validation of a high throughput LC–MS/MS method for simultaneous quantitation of pioglitazone and telmisartan in rat plasma and its application to a pharmacokinetic study. Journal of pharmaceutical analysis. 2017;7(6):381-7. 
  • Choudhury H, Gorain B, Paul A, Sarkar P, Dan S, Chakraborty P, Pal TK. Development and validation of an LC-MS/MS-ESI method for comparative pharmacokinetic study of ciprofloxacin in healthy male subjects. Drug research. 2017;67(02):94-102. 

2016

  • Gorain B, Choudhury H, Tekade RK, Karan S, Jaisankar P, Pal TK. Comparative biodistribution and safety profiling of olmesartan medoxomil oil-in-water oral nanoemulsion. Regulatory Toxicology and Pharmacology. 2016;82:20-31. 

2015

  • Chall S, Mati SS, Gorain B, Rakshit S, Bhattacharya SC. Toxicological assessment of PEG functionalized f-block rare earth phosphate nanorods. Toxicology Research. 2015;4(4):966-75. 

2014

  • Gorain B, Choudhury H, Kundu A, Sarkar L, Karmakar S, Jaisankar P, Pal TK. Nanoemulsion strategy for olmesartan medoxomil improves oral absorption and extended antihypertensive activity in hypertensive rats. Colloids and Surfaces B: Biointerfaces. 2014;115:286-94.  
  • Choudhury H, Gorain B, Karmakar S, Biswas E, Dey G, Barik R, Mandal M, Pal TK. Improvement of cellular uptake, in vitro antitumor activity and sustained release profile with increased bioavailability from a nanoemulsion platform. International journal of pharmaceutics. 2014;460(1-2):131-43. 
  • Gorain B, Chakraborty S, Pal MM, Sarkar R, Samanta SK, Karmakar S, Sen T. Arylamine N-acetyl Transferase (NAT) in the blue secretion of Telescopium telescopium: xenobiotic metabolizing enzyme as a biomarker for detection of environmental pollution. SpringerPlus. 2014;3(1):666.
  • Dan S, Choudhury H, Sarkar P, Gorain B, Barik A, Ghosh B, Pal TK. A randomized two-way crossover comparative pharmacokinetic study of two different tablet formulations containing ilaprazole in healthy human Indian volunteers. Archives of Medicine and Health Sciences. 2014;2(2):160.
  • Dan S, Ghosh B, Gorain B, Pal TK. Mandatory Registration of the Research Ethics Committees in India. Applied Clinical Research, Clinical Trials & Regulatory Affairs. 2014;1,88-92.
  • Choudhury H, Gorain B, Das A, Ghosh B, Pal T. Development and validation of a sensitive HPLC-MS/MS-ESI method for determination of febuxostat: Application to pharmacokinetic study. Current Analytical Chemistry. 2014;10(4):528-36. 

2013

  • Gorain B, Choudhury H, Biswas E, Barik A, Jaisankar P, Pal TK. A novel approach for nanoemulsion components screening and nanoemulsion assay of olmesartan medoxomil through a developed and validated HPLC method. RSC Advances. 2013;3(27):10887-93. 
  • Gorain B, Choudhury H, Halder D, Sarkar AK, Sarkar P, Biswas E, Ghosh B, Pal TK. A comparative pharmacokinetic study of a fixed dose combination for essential hypertensive patients: a randomized crossover study in healthy human volunteers. Drug research. 2013;63(04):177-84. 
  • Choudhury H, Gorain B, Karmakar S, Pal TK. Development and validation of RP-HPLC method: scope of application in the determination of oil solubility of paclitaxel. Journal of chromatographic science. 2013;52(1):68-74. 
  • Gorain B, Choudhury H, Nandi U, Das A, Dan S, Pal TK. Development and validation of an HPLC method for simultaneous detection and quantification of paracetamol and etodolac in human plasma and its application to a pharmacokinetic study. Journal of AOAC International. 2013;96(3):573-9. 
  • Nandi U, Das A, Roy B, Choudhury H, Gorain B, Pal TK. Development and validation of an HPLC?UV method for simultaneous determination of zidovudine, lamivudine, and nevirapine in human plasma and its application to pharmacokinetic study in human volunteers. Drug testing and analysis. 2013;5(6):485-91. 

2012

  • Senthil Kumar KT, Puia Z, Samanta SK, Barik R, Dutta A, Gorain B, Roy DK, Adhikari D, Karmakar S, Sen T. The Gastroprotective role of Acanthus ilicifolius–A study to unravel the underlying mechanism of anti-ulcer activity. Scientia pharmaceutica. 2012;80(3):701-18. 

2011

  • Nandi U, Gorain B, Choudhury H, Roy B, Pal TK. Development and validation of a high-performance liquid chromatographic method with ultraviolet detection for quantitation of lornoxicam in human plasma: Application to bioequivalence study. J Pharm Res. 2011;4:3203-5.

2008

  • Kumar KM, Gorain B, Roy DK, Samanta SK, Pal M, Biswas P, Roy A, Adhikari D, Karmakar S, Sen T. Anti-inflammatory activity of Acanthus ilicifolius. Journal of ethnopharmacology. 2008;120(1):7-12. 
  Member of Professional Bodies
 
  • Life membership with The Indian Pharmaceutical Association, India since 2017.
  • Registered pharmacist with West Bengal Pharmacy Council, Kolkata, India since 2003.
  Current Sponsored Projects
 

1. Start-up Research Grant entitled "Mechanistic insight of healing diabetic wound by different varieties of honey via regulating the expression of adenosine monophosphate-activated protein kinase (AMPK), hypoxia inducible factor-1α (HIF-1α) and inflammatory cytokines with special emphasis on identification of active component in honey" from Science and Engineering Research Board (SERB), New Delhi.
Role: Principal Investigator
2. Seed Money Project entitled "Wound healing potential of naringin via regulating the expression of adenosine monophosphate-activated protein kinase (AMPK) and hypoxia inducible factor-1α (HIF-1α) in experimentally induced diabetic animals" from Birla Institute of Technology, Mesra, Ranchi
Role: Principal Investigator
3. "Protein nanoparticles integrated biodegradable microneedle patch: Preclinical investigation on extended therapeutic effect of apremilast through localized intradermal delivery for Psoriasis" from Indian Council of Medical Research, Govt. of India, New Delhi, India.
Role: Co-investigator
  Text and Reference Books
 

Book chapters:

  • Pandey, M., Gorain, B., Kushwaha, S.P., Gulati, N., Mayuren, J. and Butt, A.M., 2023. Antibody–drug conjugate: Emerging trend for targeted treatment. Polymer-Drug Conjugates, pp.347-387.
  • Gorain, B., Choudhury, H., Nair, A.B. and Al-Dhubiab, B.E., 2023. Dendrimers: an effective drug delivery and therapeutic approach. In Design and Applications of Theranostic Nanomedicines (pp. 125-142). Woodhead Publishing.
  • Choudhury, H., Gorain, B., Pandey, M., Nirmal, J. and Kesharwani, P., 2022. Surface engineering of nanoparticles for imparting multifunctionality. In Nanoparticle Therapeutics (pp. 181-210). Academic Press.
  • Kokare, C.R., Khot, S.V., Gorain, B. and Kesharwani, P., 2021. Characterization of dendrimers. In Dendrimer-based nanotherapeutics (pp. 125-141). Academic Press.Gorain, B., Choudhury, H., Sengupta, P., Verma, R.K., and Pandey, M. (2021) Extrapolation from clinical trial to practice: Current pharmacotherapy on obesity. In Obesity and its Impact on Health, p.125. Springer
  • Gorain, B., Pandey, M., Choudhury, H., Jain, G.K. and Kesharwani, P., (2021) Dendrimer for solubility enhancement. In Dendrimer-Based Nanotherapeutics (pp. 273-283). Academic Press.
  • Choudhury, H., Sisinthy, S.P., Gorain, B. and Kesharwani, P. (2021) History and introduction of dendrimers. In Dendrimer-Based Nanotherapeutics (pp. 1-14). Academic Press.
  • Kumbhar, S.A., Gorain, B., Choudhury, H. and Kesharwani, P., (2021) Safety and toxicity issues of dendrimers. In Dendrimer-Based Nanotherapeutics (pp. 143-162). Academic Press.
  • Choudhury, H., Gorain, B. and Kesharwani, P. (2021) Physiology of the biological barriers. In Theory and Applications of Nonparenteral Nanomedicines (pp. 79-95). Academic Press.
  • Gorain, B., Sisinthy, S. P., Choudhury, H., & Kesharwani, P. (2021) Nanomedicine for inflammatory bowel disease. In Theory and Applications of Nonparenteral Nanomedicines (pp. 209-233). Academic Press.
  • Gorain, B., Choudhury, H., Sisinthy, S.P., & Kesharwani, P. (2020) Polymeric micelle-based drug delivery systems for tuberculosis treatment. In Nanotechnology Based Approaches for Tuberculosis Treatment. pp. 175-191.
  • Gorain, B., Sengupta, P., Dutta, S., Pandey, M., Choudhury, H. (2020) Pharmacology of Histamine, Its Receptors and Antagonists in the Modulation of Physiological Functions. In Frontiers in Pharmacology of Neurotransmitters (pp 213-240). Springer, Singapore.
  • Gorain B, Choudhury H, Pandey M, Kokare C, Khurana RK, Sehdev A, Kesharwani P. Polyester, Polyhydroxyalkanoate Nanoparticles as a Promising Tool for Anticancer Therapeutics. In Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics 2019 (pp. 101-121). Academic Press. 
  • Gorain B, Choudhury H, Pandey M, Nair AB, Amin MC, Molugulu N, Deb PK, Tripathi PK, Khurana S, Shukla R, Kohli K. Dendrimer-Based Nanocarriers in Lung Cancer Therapy. In Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer 2019 (pp. 161-192). Academic Press.
  • Gorain B, Bhattamishra SK, Choudhury H, Nandi U, Pandey M, Kesharwani P. Overexpressed Receptors and Proteins in Lung Cancer. In Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer 2019 (pp. 39-75). Academic Press.
  • Choudhury H, Pandey M, Gorain B, Chatterjee B, Madheswaran T, Md S, Mak KK, Tambuwala M, Chourasia MK, Kesharwani P. Nanoemulsions as Effective Carriers for the Treatment of Lung Cancer. In Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer 2019 (pp. 217-247). Academic Press.
  • Aung HH, Sivakumar A, Gholami SK, Venkateswaran SP, Gorain B. An Overview of the Anatomy and Physiology of the Lung. In Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer 2019 (pp. 1-20). Academic Press.
  • Tambe V, Maheshwari R, Chourasiya Y, Choudhury H, Gorain B, Tekade RK. Clinical Aspects and Regulatory Requirements for Nanomedicines. In Basic Fundamentals of Drug Delivery 2019 (pp. 733-752). Academic Press.
  • Tekade M, Maheshwari N, Choudhury H, Gorain B, Deb PK, Tekade RK, Sharma MC. Up-to-Date Implications of Nanomaterials in Dental Science. In Biomaterials and Bionanotechnology 2019 (pp. 301-336). Academic Press.
  • Gorain B, Choudhury H, Pandey M, Amin MC, Singh B, Gupta U, Kesharwani P. Dendrimers as Effective Carriers for the Treatment of Brain Tumor. In Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors 2018 (pp. 267-305). Academic Press.
  • Choudhury H, Gorain B, Madheswaran T, Pandey M, Kesharwani P, Tekade RK. Drug Complexation: Implications in Drug Solubilization and Oral Bioavailability Enhancement. In Dosage Form Design Considerations 2018 (pp. 473-512). Academic Press.
  • Gorain B, Choudhury H, Pandey M, Madheswaran T, Kesharwani P, Tekade RK. Drug–Excipient Interaction and Incompatibilities. In Dosage Form Design Parameters 2018 (pp. 363-402). Academic Press.
     
  Member, Editorial Board
 

 

  • International Journal of Pharmaceutical Investigation (https://jpionline.org/editorial-team/)