Birla Institute of Technology, Mesra
Dr. Gopal Pramanik
Assistant Professor, Pharmaceutical Sciences and Tech
PhD 		Contact Address
Permanent Address South Shibpur, Debnibas, Fresergunj Coastal, South 24 PGS, West Bengal, India 743357
Local Address Department of Pharmaceutical Sciences & Technology Birla Institute of Technology Mesra Ranchi - 835 215 (Jharkhand) FAX: 0651-2275290
Phone (Office) 0651-2274326
Phone Residence +91-9775843573
Email Id gopal.pramanik@bitmesra.ac.in
Joined Institute on : 27-Feb-2024
  Work Experience
 
Teaching : 1.5 Years

Research : 18 Years

Individual: 18.5 Years
  Professional Background
Professional Appointments:
Feb 2022 to now: Assistant Professor, Division of Pharmacology, Department of Pharmaceutical Sciences and Technology, BIT, Mesra, Ranchi, Jharkhand, India
Jul-Dec 2022: Postdoctoral Researcher, Department of Physiology, Charles University,  Prague, Czech Republic, with Prof. John Jefferys, University of  Oxford, UK and Charles University, Prague, Czech Republic
Jul 2015-June 2021: Postdoctoral Researcher, Department of Medicine,  Stanford University, CA, USA, with Prof. Matthew Wheeler, Prof. Anthony J.  Ricci, Prof. Stefan Heller, Prof. Euan Ashley, Prof. Mirna Mustapha
Mar-Jul 2015: Assistant Professor at Shinshu University, Matsimoto, Nagano, Japan
Aug 2007- Dec 2011: Researcher, Institute of Physiology, Faculty of Medicine, Otto-von-Guericke-University, Magdeburg, Germany with Prof. Volkmar Lessmann
March 2005-May 2007: Researcher, School of Biological Sciences, Nanyang Technological University, Singapore with Prof. Koh Cheng Gee
Education:
2012-2015: PhD in Neuroscience, National Institute for Physiological Sciences (NIPS), The Graduate University for Advanced Studies, Japan.
PhD Thesis: Analysis of Cell Adhesion Molecules in Synapse Formation and Synaptic Transmission (Prof. Katsuhiko Tabuchi, PhD supervisor).
2002-2004: MTech in Biotechnology and Biochemical Engineering, Department of Biotechnology, Indian Institute of Technology Kharagpur (IIT Kharagpur), India. 
Master Thesis: Expression of recombinant human FGF8b in plants by transformation using Agrobacterium rhizogenes and Agrobacterium tumefaciens mediated vacuum infiltration; and raising polyclonal anti-FGF8b antibodies in the rabbit. (Prof. Satyahari Dey, supervisor).
1998-2002: Bachelor of Pharmaceutical Technology, Department of Pharmaceutical Technology, Jadavpur University, WB, India.
  Research Areas
 

Main research interest of my laboratory is to investigate cellular mechanisms of excitable cells in multi organs diseases. Target cells of interest are neuron, cardiomyocytes, cochlear inner hair cells and neurons, and various stem cells. We use rat and mice models. 

Pharmacology; Patch clamp electrophysiology;  In vivo electrophysiology-EEG, ECG, respiratory signals in rat model; High throughput drugs screening using Multi electrodes arrays (MEA); Live cells imaging and calcium imaging; Stem cell biology and regenerative medicine; Genetics; Brain and heart research; Hearing loss; Bioinformatics and data science; Molecular and cell biology, Biochemistry; Plant Biology; Primary cells cultures and other cell cultures. 
  Award and Honours
 
  1. Postdoctoral Research Fellowship, Charles University, Czech Republic, from June 2022-Dec 2022.
  2. Postdoctoral Research Fellowship, Stanford University, USA, from July 2015-June 2021.
  3. Research Assistantship, National Institute for Physiological Sciences, SOKENDAI (The  Graduate University of Advanced Studies), Okazaki, Japan, 2012-2013. Department of  Molecular and Cellular Physiology, Shunshu University School of Medicine, Japan,2013-2015.
  4. Symposium speaker: Gopal Pramanik (2014) Synapse formation and function regulated by structural alteration of Nrxs. S2: S2-1 Synapses, Neural Circuits, and neuropsychiatric disorder. KSBMB (Korean Society for Biochemistry and Molecular Biology) Annual Meeting. May 14, Seoul, South Korea.
  5. Travel grant to visit National Institute for Physiological Sciences, SOKENDAI (The Graduate University of Advanced Studies), Okazaki, Japan in 2012.
  6. Ministry of human resources development (MHRD), India scholarship for master degree program in Indian Institute of Technology Kharagpur, India. 2002-2004.
  7. Emami Award Winner from Indian Pharmaceutical association (IPA), State of West Bengal branch as a highest GATE (graduate aptitude test in engineering) scorer with all India rank 72 in 2002
  Publications
 
  • Jennifer C Schymick, Peter Leahy, Tina Cowan, Maura R Z Ruzhnikov, Ryan Gates, Liliana Fernandez, Pramanik G, Undiagnosed Diseases Network, Vamsi Yarlagadda, Matthew Wheeler, Jonathan A Bernstein, Gregory M Enns, Chung L.Variable clinical severity in TANGO2 deficiency: Case series and literature review.Am J Med Genet A, 2022 Feb;188(2):473-487.
  • Han KA, Ko JS, Pramanik G, Kim JY, Tabuchi K, Um JW, Ko J (2018). PTPσ Drives Excitatory Presynaptic Assembly via Various Extracellular and Intracellular Mechanisms. Journal of Neuroscience. 2018 Jul 25;38(30):6700-6721, DOI: 10.1523/JNEUROSCI.0672-18.2018.
  • Um JW, Pramanik G, Ko JS, Song MY, Lee D, Kim H, Park KS, **Südhof TC, Tabuchi K and Ko J (2014). Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins,Cell Reports, 6(6):1096-1109, DOI: 10.1016/j.celrep.2014.02.010. (**Südhof TC- Nobel Prize winner in Physiology and Medicine in 2013).
  • Tabuchi K, Hang W, Asgar NF, Pramanik G. (2014) Synapse maturation and autism: learning from neuroligin model mice. Nihon Shinkei Seishin Yakurigaku Zasshi, 34(1):1-4. Japanese, PMID: 25069265.
  • Ji Seung Ko, *Gopal Pramanik, Ji Won Um, Ji Seon Shim, Kee Hun Kim, GugYoung Chung, Minhye Kim, Ho Min Kim, Joris de Wit, Kang-Sik Park, Katsuhiko Tabuchi, Jaewon Ko (2015). PTPσ acts as a presynaptic receptor for glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission. Proceedings of the National Academy of Sciences USA. Feb 10;112(6):1874-9, DOI: 10.1073/pnas.1410138112, (*Co-first author).
  • Pramanik S., Pramanik G*. (2016) Nanotechnology for Sustainable Agriculture in India. In: Ranjan S., Dasgupta N., Lichtfouse E. (eds) Nanoscience in Food and Agriculture 3. Sustainable Agriculture Reviews, vol 23. Springer, Cham. DOI: 10.1007/978-3-319-48009- 1_10, (*Corresponding Author).