Birla Institute of Technology, Mesra
   
Dr. Animesh Ghosh
Associate Professor, Pharmaceutical Sciences and Tech
M. Pharm., Ph.D.
Contact Address
Permanent Address Quarter No: CII/68 Outer Campus Birla Institute of Technology, Mesra Ranchi - 835215, Jharkhand, India
Local Address Department of Pharmaceutical Sciences & Technology Birla Institute of Technology, Mesra Ranchi - 835215, Jharkhand, India
Phone (Office) 06512275290
Phone Residence 09007175618/09470339587
Email Id aghosh@bitmesra.ac.in
Joined Institute on : 30-Nov-2009
  Work Experience
 
Teaching : 11 Years

Research : 15 Years

  Research Areas
 

Solid State Pharmaceutics, Pharmaceutical Cocrystals, Solid Dosage Form of Pharmaceutical Cocrystals, Bioavailability  Study, modification of biopolymer for controlled drug delivery system. 

  Award and Honours
 

BIRAC-SRISTI-GYTI Award 2017 (Awradee: Dr. Subham Banerjee, completed his PhD under the joint guidance of Animesh Ghosh (BIT, Mesra) and Dr. Pronobesh Chattopadhyay (DRL, Tezpur))

   Publications
 
1    Bhattacharya, Biswajit; Das, Susobhan; Lal, Garima; Soni, Saundray Raj; Ghosh, Animesh; Reddy, C Malla; Ghosh, Soumyajit;     Screening, crystal structures and solubility studies of a series of multidrug salt hydrates and cocrystals of fenamic acids with trimethoprim and sulfamethazine    Journal of Molecular Structure    1199        127028    2020
2    Roy, Parag; Ghosh, Animesh;     Mechanochemical cocrystallization to improve the physicochemical properties of chlorzoxazone    CrystEngComm                2020
3    Roy, Arpita; Samanta, Subhendu; Singha, Koushik; Maity, Pritiprasanna; Kumari, Nimmy; Ghosh, Animesh; Dhara, Santanu; Pal, Sagar;     Development of a Thermoresponsive Polymeric Composite Film Using Cross-Linked β-Cyclodextrin Embedded with Carbon Quantum Dots as a Transdermal Drug Carrier    ACS Applied Bio Materials    3    5    3285-3293    2020
4    Kumari, Nimmy; Ghosh, Animesh;     Cocrystallization: Cutting Edge Tool for Physicochemical Modulation of Active Pharmaceutical Ingredients    Current Pharmaceutical Design                2020
5    Bera, Sumit; Maity, Subhasis; Ghosh, Balaram; Ghosh, Animesh; Giri, Tapan K;     Development and Characterization of Solid Dispersion System for Enhancing the Solubility and Dissolution Rate of Dietary Capsaicin    Current Drug Therapy    15    2    143-151    2020
6    Roy, Anupam; Sarkar, Biswatrish; Celik, Cagla; Ghosh, Animesh; Basu, Utpal; Jana, Malabendu; Jana, Arundhati; Gencay, Ayse; Ildiz, N; Dam, P;     Can concomitant use of zinc and curcumin with other immunity-boosting nutraceuticals be the arsenal against COVID-19?    Phytotherapy Research: PTR                2020
7    Roy, Parag; Ghosh, Animesh;     Progress on cocrystallization of poorly soluble NME's in the last decade    CrystEngComm                2020
8    Patra, Priyapratim; Soni, Saundray Raj; Seesala, Venkata Sundeep; Dhara, Santanu; Ghosh, Animesh; Pal, Sagar;     Synthesis of a novel copolymer using glycogen and poly (lactide) as a carrier of dual drugs—ornidazole and ofloxacin    Journal of Polymer Science Part A: Polymer Chemistry    57    15    1697-1703    2019
9    Patra, Priyapratim; Seesala, Venkata Sundeep; Soni, Saundray Raj; Roy, Rakesh Kumar; Dhara, Santanu; Ghosh, Animesh; Patra, Niladri; Pal, Sagar;     Biopolymeric pH-responsive fluorescent gel for in-vitro and in-vivo colon specific delivery of metronidazole and ciprofloxacin    European Polymer Journal    114        255-264    2019
10    Kumari, Nimmy; Bhattacharya, Biswajit; Roy, Parag; Michalchuk, Adam AL; Emmerling, Franziska; Ghosh, Animesh;     Enhancing the Pharmaceutical Properties of Pirfenidone by Mechanochemical Cocrystallization    Crystal Growth & Design    19    11    6482-6492    2019
11    Soni, Saundray Raj; Ghosh, Animesh;     Thermo-and ultrasound-responsive polysaccharides for controlled drug delivery    Polysaccharide Carriers for Drug Delivery            217-270    2019
12    Soni, Saundray Raj; Kumari, Nimmy; Bhunia, Bibhas K; Sarkar, Biswatrish; Mandal, Biman B; Ghosh, Animesh;     Synthesis and characterization of a non-cytotoxic and biocompatible acrylamide grafted pullulan–Application in pH responsive controlled drug delivery    International journal of biological macromolecules                2018
13    Soni, Saundray Raj; Kumari, Nimmy; Bhunia, Bibhas K; Sarkar, Biswatrish; Mandal, Biman B; Ghosh, Animesh;     In vitro and in vivo evaluation of pirfenidone loaded acrylamide grafted pullulan-poly (vinyl alcohol) interpenetrating polymer networks    Carbohydrate Polymers                2018
14    Soni, Saundray Raj; Bhunia, Bibhas K; Kumari, Nimmy; Dan, Subhashis; Mukherjee, Sudipta; Mandal, Biman B; Ghosh, Animesh;     Therapeutically Effective Controlled Release Formulation of Pirfenidone from Nontoxic Biocompatible Carboxymethyl Pullulan-Poly (vinyl alcohol) Interpenetrating Polymer Networks    ACS Omega    3    9    11993-12009    2018
15    Bhattacharya, Biswajit; Mondal, Amit; Soni, Saundray Raj; Das, Susobhan; Bhunia, Surojit; Raju, K Bal; Ghosh, Animesh; Reddy, C Malla;     Multidrug salt forms of norfloxacin with non-steroidal anti-inflammatory drugs: solubility and membrane permeability studies    CrystEngComm                2018
16    Kundu, Sudeshna; Kumari, Nimmy; Soni, Saundray Raj; Ranjan, Subham; Kumar, Rajan; Sharon, Ashoke; Ghosh, Animesh;     Enhanced Solubility of Telmisartan Phthalic Acid Cocrystals within the pH Range of a Systemic Absorption Site    ACS Omega    3    11    15380-15388    2018
17    Soni, Saundray R; Ghosh, Animesh;     Grafting onto biopolymers: application in targeted drug delivery    Biopolymer Grafting            335-389    2018
18    Kumar, P Mahesh; Ghosh, Animesh;     Development and evaluation of silver sulfadiazine loaded microsponge based gel for partial thickness (second degree) burn wounds    European Journal of Pharmaceutical Sciences    96        243-254    2017
19    Ranjan, Subham; Devarapalli, Ramesh; Kundu, Sudeshna; Vangala, Venu R; Ghosh, Animesh; Reddy, C Malla;     Three new hydrochlorothiazide cocrystals: Structural analyses and solubility studies    Journal of Molecular Structure    1133        405-410    2017
20    Soni, Saundray Raj; Ghosh, Animesh;     Exploring pullulan-poly (vinyl alcohol) interpenetrating network microspheres as controlled release drug delivery device    Carbohydrate Polymers                2017
21    Mandal, Barun; Rameshbabu, Arun Prabhu; Soni, Saundray Raj; Ghosh, Animesh; Dhara, Santanu; Pal, Sagar;     In-situ Silver Nanowires Deposited Cross linked Carboxymethyl Cellulose: A Potential Transdermal Anticancer Drug Carrier    ACS Applied Materials & Interfaces                2017
22    Isaac, Jinu; Ganguly, Swastika; Ghosh, Animesh;     Comilling of telmisartan with poly (vinyl alcohol)–an alkalanizer free green approach to ensure its bioavailability    European Journal of Pharmaceutics and Biopharmaceutics                2016
23    Kaity, Santanu; Ghosh, Animesh;     Facile preparation of acrylamide grafted locust bean gum-poly (vinyl alcohol) interpenetrating polymer network microspheres for controlled oral drug delivery    Journal of Drug Delivery Science and Technology                2016
24    Banerjee, Subham; Chattopadhyay, Pronobesh; Ghosh, Animesh; Bhatnagar, Aseem; Veer, Vijay;     Pharmacokinetic and biodistribution study of eserine and pralidoxime chloride in rabbits following a single application of a transdermal patch    European journal of drug metabolism and pharmacokinetics    41    3    219-230    2016
25    Kaity, Santanu; Ghosh, Animesh;     Comparative bio-safety and in vivo evaluation of native or modified locust bean gum-PVA IPN microspheres    International journal of biological macromolecules    72        883-893    2015
26    Das, Raghunath; Das, Dipankar; Ghosh, Paulomi; Ghosh, Animesh; Dhara, Santanu; Panda, AB; Pal, Sagar;     Novel pH-responsive graft copolymer based on HPMC and poly (acrylamide) synthesised by microwave irradiation: application in controlled release of ornidazole    Cellulose    22    1    313-327    2015
27    Ghosh, Animesh; Banerjee, Subham; Kaity, Santanu; W Wong, Tin;     Current pharmaceutical design on adhesive based transdermal drug delivery systems    Current pharmaceutical design    21    20    2771-2783    2015
28    Das, Dipankar; Ghosh, Paulomi; Ghosh, Animesh; Haldar, Chanchal; Dhara, Santanu; Panda, Asit Baran; Pal, Sagar;     Stimulus-responsive, Biodegradable, Biocompatible, Covalently Crosslinked Hydrogel Based on Dextrin and Poly (N-isopropyl acrylamide) for In-vitro/In-vivo Controlled Drug Release    ACS applied materials & interfaces                2015
29    Mahesh Kumar, P; Ghosh, Animesh;     Development and evaluation of metronidazole loaded microsponge based gel for superficial surgical wound infections    Journal of Drug Delivery Science and Technology    30        15-29    2015
30    Das, Dipankar; Das, Raghunath; Mandal, Jayanta; Ghosh, Animesh; Pal, Sagar;     Dextrin crosslinked with poly (lactic acid): A novel hydrogel for controlled drug release application    Journal of Applied Polymer Science    131    7        2014
31    Banerjee, Subham; Chattopadhyay, Pronobesh; Ghosh, Animesh; Bhattacharya, Shiv Sankar; Kundu, Amit; Veer, Vijay;     Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning    Journal of Food and Drug Analysis                2014
32    Banerjee, Subham; Chattopadhyay, Pronobesh; Ghosh, Animesh; Pathak, Manash Pratim; Gogoi, Jyotchna; Veer, Vijay;     Protection by a transdermal patch containing eserine and pralidoxime chloride for prophylaxis against (±)-Anatoxin A poisoning in rats    European Journal of Pharmaceutical Sciences    56        28-36    2014
33    Sugandha, Kumari; Kaity, Santanu; Mukherjee, Samrat; Isaac, Jinu; Ghosh, Animesh;     Solubility Enhancement of Ezetimibe by a Cocrystal Engineering Technique    Crystal Growth & Design    14    9    4475-4486    2014
34    Banerjee, Subham; Chattopadhyay, Pronobesh; Ghosh, Animesh; Datta, Pinaki; Veer, Vijay;     Aspect of adhesives in transdermal drug delivery systems    International Journal of Adhesion and Adhesives    50        70-84    2014
35    GHOSH, ANIMESH; WONG, TINWUI;     GRAFT COPOLYMERS OF GUAR GUM VERSUS ALGINATE: DRUG DELIVERY APPLICATIONS AND IMPLICATIONS    Physical Chemistry of Macromolecules: Macro to Nanoscales            423    2014
36    Kaity, Santanu; Isaac, Jinu; Ghosh, Animesh;     Interpenetrating polymer network of locust bean gum-poly (vinyl alcohol) for controlled release drug delivery    Carbohydrate polymers    94    1    456-467    2013
37    Isaac, Jinu; Kaity, Santanu; Ganguly, Swastika; Ghosh, Animesh;     Microwave?induced solid dispersion technology to improve bioavailability of glipizide    Journal of Pharmacy and Pharmacology    65    2    219-229    2013
38    Kaity, Santanu; Ghosh, Animesh;     Carboxymethylation of locust bean gum: Application in interpenetrating polymer network microspheres for controlled drug delivery    Industrial & Engineering Chemistry Research    52    30    10033-10045    2013
39    Kaity, Santanu; Isaac, Jinu; Kumar, P Mahesh; Bose, Anirbandeep; Wong, Tin Wui; Ghosh, Animesh;     Microwave assisted synthesis of acrylamide grafted locust bean gum and its application in drug delivery    Carbohydrate polymers    98    1    1083-1094    2013
40    Banerjee, Subham; Chattopadhyay, Pronobesh; Ghosh, Animesh; Goyary, Danswrang; Karmakar, Sanjeev; Veer, Vijay;     Influence of process variables on essential oil microcapsule properties by carbohydrate polymer–protein blends    Carbohydrate polymers    93    2    691-697    2013
41    Banerjee, Subham; Chattopadhyay, Pronobesh; Ghosh, Animesh; Pathak, Manash Pratim; Singh, Shweta; Veer, Vijay;     Acute Dermal Irritation, Sensitization, and Acute Toxicity Studies of a Transdermal Patch for Prophylaxis Against (±) Anatoxin-A Poisoning    International journal of toxicology            1.09158E+15    2013
42    Banerjee, Subham; Siddiqui, Lubna; Bhattacharya, Shiv Sankar; Kaity, Santanu; Ghosh, Animesh; Chattopadhyay, Pronobesh; Pandey, Anurag; Singh, Lokendra;     Interpenetrating polymer network (IPN) hydrogel microspheres for oral controlled release application    International journal of biological macromolecules    50    1    198-206    2012
43    Vijan, Veena; Kaity, Santanu; Biswas, Soumen; Isaac, Jinu; Ghosh, Animesh;     Microwave assisted synthesis and characterization of acrylamide grafted gellan, application in drug delivery    Carbohydrate polymers    90    1    496-506    2012
44    Pal, Sagar; Ghorai, S; Das, C; Samrat, S; Ghosh, A; Panda, Asit Baran;     Carboxymethyl tamarind-g-poly (acrylamide)/silica: a high performance hybrid nanocomposite for adsorption of methylene blue dye    Industrial & Engineering Chemistry Research    51    48    15546-15556    2012
45    Bhattacharya, Shiv Sankar; Sen, Kalyan Kumar; Sen, Suma Oommen; Banerjee, Subham; Kaity, Santanu; Ghosh, Ashoke Kumar; Ghosh, Animesh;     Synthesis and characterization of poly (acrylic acid)/modified bentonite superabsorbent polymer    International Journal of Polymeric Materials    60    13    1015-1025    2011
46    Banerjee, Subham; Verma, Sushma; Pal, Dilipkumar; Ghosh, Ashoke Kumar; Bhattacharya, Shiv Sankar; Chattopadhyay, Pronobesh; Ghosh, Animesh; Kaity, Santanu;     Fabrication and assessment of polyacrylate/(guar gum modified bentonite) superabsorbent polymeric composite    Journal of polymer Engineering    31    08-Sep    567-575    2011
47    Banerjee, Subham; Chaurasia, Gaurav; Pal, DK; Ghosh, Ashoke Kumar; Ghosh, Animesh; Kaity, Santanu;     Investigation on crosslinking density for development of novel interpenetrating polymer network (IPN) based formulation    Journal of Scientific and Industrial Research    69    10    777-784    2010
48    Banerjee, SUBHAM; Ray, SOMASREE; Maiti, SABYASACHI; Sen, KALYAN KUMAR; Bhattacharyya, UK; Kaity, S; Ghosh, ANIMESH;     Interpenetrating polymer network (IPN): a novel biomaterial    Int. J. Appl. Pharm    2    1    28-34    2010
49    Kaity, Santanu; Maiti, Sabyasachi; Ghosh, Ashoke Kumar; Pal, Dilipkumar; Ghosh, Animesh; Banerjee, Subham;     Microsponges: A novel strategy for drug delivery system    Journal of advanced pharmaceutical technology & research    1    3    283    2010
50    Sengupta, Pinaki; Bhaumik, Uttam; Ghosh, Animesh; Sarkar, Amlan Kanti; Chatterjee, Bappaditya; Bose, Anirbandeep; Pal, Tapan Kumar;     LC–MS–MS development and validation for simultaneous quantitation of Metformin, Glimepiride and Pioglitazone in human plasma and its application to a bioequivalence study    Chromatographia    69    11-Dec    1243-1250    2009
51    Bhaumik, Uttam; Ghosh, Animesh; Chatterjee, Bappaditya; Sengupta, Pinaki; Darbar, Soumendra; Roy, Bikash; Nandi, Utpal; Pal, Tapan K;     Development and validation of a high-performance liquid chromatographic method for bioanalytical application with rimonabant    Journal of pharmaceutical and biomedical analysis    49    4    1009-1013    2009
52    Chakrabarty, Uday Sankar; Das, Ayan; Bhaumik, Uttam; Chatterjee, Bappaditya; Ghosh, Animesh; Bose, Anirbandeep; Sengupta, Pinaki; Nandi, Utpal; Pal, Tapan K;     Rapid and sensitive LC method for the analysis of gemifloxacin in human plasma    Chromatographia    69    09-Oct    853-858    2009
53    Bose, Anirbandeep; Bhaumik, Uttam; Ghosh, Animesh; Chatterjee, Bappaditya; Chakrabarty, Uday Sankar; Sarkar, Amlan Kanti; Pal, Tapan Kumar;     LC–MS Simultaneous Determination of Itopride Hydrochloride and Domperidone in Human Plasma    Chromatographia    69    11-Dec    1233-1241    2009
54    Das, Ayan; Bhaumik, Uttam; Chakrabarty, Uday S; Sarkar, Amlan Kanti; Ghosh, Animesh; Bose, Anirbandeep; Chatterjee, Bappaditya; Pal, Tapan K;     Comparative bioavailability study of amisulpride tablets in healthy Indian volunteers    Arzneimittelforschung    59    4    166-170    2009
55    Bhaumik, Uttam; Ghosh, Animesh; Sarkar, Amlan Kanti; Bose, Anirbandeep; Selvan, P Senthamil; Sengupta, Pinaki; Chakraborty, Uday Sankar; Ghosh, Debotri; Pal, Tapan Kumar;     Determination of ranolazine in human plasma by LC–MS/MS and its application in bioequivalence study    Journal of pharmaceutical and biomedical analysis    48    5    1404-1410    2008
56    Mandal, Uttam; Gowda, Veeran; Ghosh, Animesh; Bose, Anirbandeep; Bhaumik, Uttam; Chatterjee, Bappaditya; Pal, Tapan Kumar;     Optimization of metformin HCl 500 mg sustained release matrix tablets using Artificial Neural Network (ANN) based on Multilayer Perceptrons (MLP) model    Chemical and Pharmaceutical Bulletin    56    2    150-155    2008
57    Ghosh, Animesh; Bhaumik, Uttam Kumar; Bose, Anirbandeep; Mandal, Uttam; Gowda, Veeran; Chatterjee, Bappaditya; Chakrabarty, Uday Sankar; Pal, Tapan Kumar;     Extended release dosage form of glipizide: development and validation of a level A in vitro-in vivo correlation    Biological and Pharmaceutical Bulletin    31    10    1946-1951    2008
58    Bhaumik, Uttam; Ghosh, Animesh; Mandal, Uttam; Chatterjee, Bappaditya; Sarkar, Amlan Kanti; Bose, Anirbandeep; Ray, Kamala Kanta; Pal, Tapan Kumar;     Determination of Drospirenone in Human Plasma by LC–Tandem-MS    Chromatographia    68    09-Oct    713-720    2008
59    Chakrabarty, Uday S; Mandal, Uttam; Bhaumik, Uttam; Chatterjee, Bappaditya; Ghosh, Animesh; Bose, Anirban; Pal, Tapan K;     Bioequivalence study of two capsule formulations containing diacerein 50 mg in healthy human subjects    Arzneimittelforschung    58    8    405-409    2008
60    Sengupta, Pinaki; Das, Ayan; Chatterjee, Bappaditya; Bhaumik, Uttam; Ghosh, Animesh; Bose, Anirbandeep; Pal, TK;     Simultaneous quantitation of rosiglitazone and glibenclamide in human plasma by LC-MS/MS; method development and validation    RESEARCH JOURNAL OF BIOTECHNOLOGY            414-418    2008
61    Bhaumik, Uttam; Ghosh, Animesh; Chakrabarty, Uday S; Mandal, Uttam; Bose, Anirbandeep; Das, Ayan; Ray, Kamala Kanta; Pal, Tapan K;     Evaluation of the bioequivalence of two faropenem formulations in healthy Indian subjects    Arzneimittel-Forschung    58    12    681-685    2008
62    Gowda, K Veeran; Mandal, Uttam; Senthamil Selvan, P; Sam Solomon, WD; Ghosh, Animesh; Sarkar, Amlan Kanti; Agarwal, Sangita; Nageswar Rao, T; Pal, Tapan Kumar;     Liquid chromatography tandem mass spectrometry method for simultaneous determination of metoprolol tartrate and ramipril in human plasma    Journal of Chromatography B    858    1    13-21    2007
63    Mandal, Uttam; Gowda, Veeran; Ghosh, Animesh; Selvan, Senthamil; Solomon, Sam; Pal, Tapan Kumar;     Formulation and optimization of sustained release matrix tablet of metformin HCl 500 mg using response surface methodology    Yakugaku zasshi    127    8    1281-1290    2007
64    Mandal, U; Ray, KK; Gowda, Veeran; Ghosh, A; Pal, TK;     In?vitro and in?vivo correlation for two gliclazide extended?release tablets    Journal of pharmacy and pharmacology    59    7    971-976    2007
 
  Member of Professional Bodies
 

Member, Association of Pharmaceutical Teachers of India (APTI)

  Current Sponsored Projects
 
As PI:
1. Title:To modulate the aqueous solubility of poorly water-soluble pharmaceuticals by crystal engineering technique and understand the mechanistic approach of solubilization.
Period: 2019 - 2022
Sponsored by: AICTE-RPS
Status: Ongoing
 
2. Title: Prophylactic Transdermal  Patch against  Neurotoxin Poisoning  in  Biological Warfare  Situations
Period: 2017-2021
Sponsored by: BIRAC-SRISTI-GYTI 
Status: Ongoing
 
3. Title: To develop chemically modified non-toxic bio polymers for therapeutically effective controlled drug delivery system.
Period: 2015 - 2018
Sponsored by: EMR, SERB-DST 
Status: Completed
 
4. Title: Improvement of bioavailability of poorly water soluble drugs by micronization and establishment of Lavel A In vitro - In Vivo correlation.
Period: 2012 - 2015
Sponsored by: UGC-MRP
Status: Completed
 
5. Title: In-vitro characterization of Microsponge loaded gel for wound healing - evaluation of safety and efficacy.
Period: 2011 - 2015
Sponsored by: DRDO
Status: Completed
 
As Co-PI
1. Bioploymer based nano-layer fortification of self-assembled micronutrients over pre-conditioned rice: Retention of fortified nutrients and scale up studies.  
Period: 2019 - 2021
Sponsored by: ICMR
Status: Ongoing
  Text and Reference Books
 
Book Chapter:
1. Ghosh, A., & Wong, T.W. (2014). Graft Copolymers of Guar Gum vs. Alginate: Drug Delivery Applications and Implications. In C.H.Chan, C.H.Chia & S. Thomas (Eds.), Physical Chemistry of Macromolecules Macro to Nanoscales (pp. 423-440). New Jersey Apple Academic Press Inc.
2. Banerjee, S., & Ghosh, A., (2016). Organic - Inorganic Nanocomposites for Biomedical Applications. In S. Maiti and K. K. Sen (Eds.), Bio-Tragets and Drug Delivery Approaches (pp. 375-403). CRC Press, Taylor & Francis Group.
3. Soni, SR., & Ghosh, A. (2017). Grafting Onto Biopolymers: Application in Targeted Drug Delivery. In Vijay Kumar Thakur (Ed). Biopolymer Grafting: Applications (335-389). Elsevier, Amsterdam, Netherlands. 
  Patent
 
Patent Title: MATRIX TYPE TRANSDERMAL PATCH FORMULATIONS
Patent No: 319521
Date of Grant: 30.08.2019
  Fellow
 

 PhD Scholar

(Awarded)

1. Santanu Kaity 

2. Subham Banerjee 

3. Jinu Isaac

4. P. Mahesh Kumar

5. Saundray Raj Soni

Ongoing

1. Nimmy Kumari

2. Parag Roy