Birla Institute of Technology, Mesra
   
Dr. Animesh Ghosh
Associate Professor, Pharmaceutical Sciences and Tech
M. Pharm., Ph.D.
Contact Address
Permanent Address Quarter No: DII/39 Birla Institute of Technology, Mesra Ranchi - 835215, Jharkhand, India
Local Address Department of Pharmaceutical Sciences & Technology Birla Institute of Technology, Mesra Ranchi - 835215, Jharkhand, India
Phone (Office) 06512275290
Phone Residence 09007175618/09470339587
Email Id aghosh@bitmesra.ac.in
Joined Institute on : 30-Nov-2009
  Work Experience
 
Teaching : 8 Years

Research : 12 Years

  Research Areas
 

Modification of Natural Polymer and its application in Drug Delivery, Pharmacokinetics, Improvement of Bioavailability, Pharmaceutical cocrystals

  Award and Honours
 

BIRAC-SRISTI-GYTI Award 2017 (Awradee: Dr. Subham Banerjee, completed his PhD under the joint guidance of Animesh Ghosh (BIT, Mesra) and Dr. Pronobesh Chattopadhyay (DRL, Tezpur))

   Publications
 
2017
49. Mandal, B, Rameshbabu, A. P, Soni, S.R, Ghosh, A, Dhara, Pal, S., (2017) In Situ Silver Nanowire Deposited Cross-Linked Carboxymethyl Cellulose: A Potential Transdermal Anticancer Drug Carrier. ACS Appllied Material Interfaces. 9. pp. 36583-36595. 
48. Soni, S. R, Ghosh, A*. (2017). Exploring pullulan-poly(vinyl alcohol) interpenetrating network microspheres as controlled release drug delivery device. Carbohydrate Polymers. 174. pp. 812-822.
47. Ranjan, S., Devarapalli, R., Kundu, S., Vangala, V.R*., Ghosh, A*., Reddy, C.M*. (2017). Three new hydrochlorothiazide cocrystals: Structural analyses and solubility studies. Journal of Molecular Structure. 1133. pp. 405-410.
46. Kumar, P.M., Ghosh, A*. (2017). Development and evaluation of silver sulfadiazine loaded microsponge based gel for partial thickness (second degree) burn wounds. European Journal of Pharmaceutical Sciences. 96. pp. 243-254.
 
2016
45. Isaac, J., Ganguly, S., Ghosh, A*. (2016). Co-milling of telmisartan with poly(vinyl alcohol) – An alkalinizer free green approach to ensure its bioavailability. European Journal of Pharmaceutics and Biopharmaceutics. 101, pp. 43-52.
44. Kaity, S., Ghosh, A*. (2016). Facile preparation of acrylamide grafted locust bean gum-poly(vinyl alcohol) interpenetrating polymer network microspheres for controlled oral drug delivery. Journal of Drug Delivery Science and Technology. 33, pp. 1-12.
43. Banerjee, S., Chattopadhyay, P., Ghosh, A., Bhatnagar, A., Veer, V. (2015). Pharmacokinetic and biodistribution study of eserine and pralidoxime chloride in rabbits following a single application of a transdermal patch. European Journal of Drug Metabolism and Pharmacokinetics.41, pp. 219-230.
 
2015 
42. Kumar, P.M., Ghosh, A*. (2015). Development and evaluation of metronidazole loaded microsponge based gel for superfacial surgical wound infections. Journal of Drug Delivery Science and Technology. 30, PP. 15-29.
41. Das, D., Ghosh, P., Ghosh, A., Haldar, C., Dhara, S., Panda, A. B., Pal, S. (2015). Stimulus-responsive, Biodegradable, Biocompatible, Covalently Crosslinked Hydrogel Based on Dextrin and Poly (N-isopropylacrylamide) for In-vitro/In-vivo Controlled Drug Release. ACS Applied Materials & Interfaces. 7, PP. 14338-14351.
40. Das, R., Das, D., Ghosh, P., Ghosh, A., Dhara, S., Panda, A.B., Pal, S. (2015). Novel pH-responsive graft copolymer based on HPMC and poly(acrylamide) synthesised by microwave irradiation:application in controlled release of ornidazole. Cellulose. 22 (1), pp. 313-327 
39. Kaity, S., Ghosh, A*. (2015). Comparative bio-safety and in vivo evaluation of native or modified locust bean gum-PVA IPN microspheres. International Journal of Biological Macromolecules. 72, pp. 883-893. 
 
2014
38. Sugandha, K., Kaity, S., Mukherjee, S., Isaac, J., Ghosh, A*. (2014). Solubility enhancement of ezetimibe by cocrystal engineering technique. Crystal Growth & Design. 14, pp. 4475-4486. 
37. Banerjee, S., Chattopadhyay, P., Ghosh, A., Pathak, M.P., Gogoi, J., Veer, V. (2014). Protection by a transdermal patch containing eserine and pralidoxime chloride for prophylaxis against (±)-Anatoxin A poisoning in rats. European Journal of Pharmaceutical Sciences. 56, pp. 28-36. 
36. Banerjee, S., Chattopadhyay, P., Ghosh, A., Bhattacharya, S.S., Kundu, A., Veer, V. (2014). Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning. Journal of Food and Drug Analysis. 22, pp. 264-270. 
35. Das, D., Das, R., Mandal, J., Ghosh, A*., Pal, S. Dextrin crosslinked with poly (lactic acid): A novel hydrogel for controlled drug release application. Journal of Applied Polymer Science. 131 (7) 40039.
 
2013
34. Kaity, S., Isaac, J., Kumar, P.M., Bose, A., Wong, T.W., Ghosh, A*. Microwave assisted synthesis of acrylamide grafted locust bean gum and its application in drug delivery. (2013) Carbohydrate Polymers, 98 (1), pp. 1083-1094. 
33. Kaity, S., & Ghosh, A*. Carboxymethylation of locust bean gum: Application in interpenetrating polymer network microspheres for controlled drug delivery. (2013) Industrial and Engineering Chemistry Research, 52 (30), pp. 10033-10045.  
32. Banerjee, S., Chattopadhyay, P., Ghosh, A., Pathak, M.P., Singh, S., Veer, V. Acute dermal irritation, sensitization, and acute toxicity studies of a transdermal patch for prophylaxis against (±) anatoxin-a poisoning. (2013) International Journal of Toxicology, 32 (4), pp. 308-313.  
31. Kaity, S., Isaac, J., Ghosh, A*. Interpenetrating polymer network of locust bean gum-poly (vinyl alcohol) for controlled release drug delivery. (2013) Carbohydrate Polymers, 94 (1), pp. 456-467. 
30. Banerjee, S., Chattopadhyay, P., Ghosh, A., Goyary, D., Karmakar, S., Veer, V. Influence of process variables on essential oil microcapsule properties by carbohydrate polymer-protein blends. (2013) Carbohydrate Polymers, 93 (2), pp. 691-697. 
29. Isaac, J., Kaity, S., Ganguly, S., Ghosh, A*. Microwave-induced solid dispersion technology to improve bioavailability of glipizide. (2013) Journal of Pharmacy and Pharmacology, 65 (2), pp. 219-229.  
28. Banerjee, S., Singh, S., Policegoudra, R., Chottopadhyay, P., Ghosh, A., Veer, V. Evaluation of mutagenic potential of a combinational prophylactic transdermal patch by Ames  test. (2013) Immuno-analyse et biologie spécialisée. 28, pp. 322-326. 
27. Banerjee, S., Chattopadhyay, P., Ghosh, A., Kaity, S., Veer, V. Development and Validation of a Reverse Phase Liquid Chromatography Method for the Simultaneous Quantification of Eserine and Pralidoxime Chloride in Drugs-in-Adhesive Matrix Type Transdermal Patches. (2013) Drug research. 63, pp. 450-456. 
 
2012
26. Pal, S., Ghorai, S., Das, C., Samrat, S., Ghosh, A., Panda, A.B. Carboxymethyl tamarind-g-poly(acrylamide)/silica: A high performance hybrid nanocomposite for adsorption of methylene blue dye. (2012) Industrial and Engineering Chemistry Research, 51 (48), pp. 15546-15556. 
25. Vijan, V., Kaity, S., Biswas, S., Isaac, J., Ghosh, A*. Microwave assisted synthesis and characterization of acrylamide grafted gellan, application in drug delivery. (2012) Carbohydrate Polymers, 90 (1), pp. 496-506. 
24. Banerjee, S., Siddiqui, L., Bhattacharya, S.S., Kaity, S., Ghosh, A., Chattopadhyay, P., Pandey, A., Singh, L. Interpenetrating polymer network (IPN) hydrogel microspheres for oral controlled release application. (2012) International Journal of Biological Macromolecules, 50 (1), pp. 198-206. 
 
2011
23. Bhattacharya, S.S., Sen, K.K., Sen, S.O., Banerjee, S., Kaity, S., Ghosh, A.K., Ghosh, A. Synthesis and characterization of poly(acrylic acid)/modified bentonite superabsorbent polymer. (2011) International Journal of Polymeric Materials and Polymeric Biomaterials, 60 (13), pp. 1015-1025.  
22. Banerjee, S., Verma, S., Pal, D., Ghosh, A.K., Bhattacharya, S.S., Chattopadhyay, P., Ghosh, A., Kaity, S. Fabrication and assessment of polyacrylate/(guar gum modifi ed bentonite) superabsorbent polymeric composite. (2011) Journal of Polymer Engineering, 31 (8-9), pp. 567-575. 
 
2010
21. Bhaumik, U., Bose, A., Chatterjee, B., Ghosh, A., Sengupta, P., Agarwal, S., Das, A., Pal, T.K. Stability-indicating HPLC method for the determination of oxcarbazepine in pharmaceutical formulation. (2010) Asian Journal of Chemistry, 22 (3), pp. 2051-2057. 
20. Banerjee, S., Chaurasia, G., Pal D, K., Ghosh, A, K., Ghosh, A., Kaity, S.  Investigation on crosslinking density for development of novel interpenetrating polymer network (IPN) based formulation. (2010) Journal of Scientific and Industrial Research. 69, pp. 777-784. 
 
2009
19. Das, A., Bhaumik, U., Chakrabarty, U.S., Sarkar, A.K., Ghosh, A., Bose, A., Chatterjee, B., Pal, T.K. Comparative bioavailability study of amisulpride tablets in healthy Indian volunteers. (2009) Drug Research, 59 (4), pp. 166-170. 
18. Sengupta, P., Bhaumik, U., Ghosh, A., Sarkar, A.K., Chatterjee, B., Bose, A., Pal, T.K. LC-MS-MS development and validation for simultaneous quantitation of metformin, glimepiride and pioglitazone in human plasma and its application to a bioequivalence study. (2009) Chromatographia, 69 (11-12), pp. 1243-1250. 
17. Bose, A., Bhaumik, U., Ghosh, A., Chatterjee, B., Chakrabarty, U.S., Sarkar, A.K., Pal, T.K. LC-MS simultaneous determination of itopride hydrochloride and domperidone in human plasma. (2009) Chromatographia, 69 (11-12), pp. 1233-1241. 
16. Bhaumik, U., Ghosh, A., Chatterjee, B., Sengupta, P., Darbar, S., Roy, B., Nandi, U., Pal, T.K. Development and validation of a high-performance liquid chromatographic method for bioanalytical application with rimonabant. (2009) Journal of Pharmaceutical and Biomedical Analysis, 49 (4), pp. 1009-1013. 
15. Chakrabarty, U.S., Das, A., Bhaumik, U., Chatterjee, B., Ghosh, A., Bose, A., Sengupta, P., Nandi, U., Pal, T.K. Rapid and sensitive LC method for the analysis of gemifloxacin in human plasma. (2009) Chromatographia, 69 (9-10), pp. 853-858.  
 
2008
14. Bhaumik, U., Ghosh, A., Sarkar, A.K., Bose, A., Selvan, P.S., Sengupta, P., Chakraborty, U.S., Ghosh, D., Pal, T.K. Determination of ranolazine in human plasma by LC-MS/MS and its application in bioequivalence study. (2008) Journal of Pharmaceutical and Biomedical Analysis, 48 (5), pp. 1404-1410. 
13. Bhaumik, U., Ghosh, A., Chakrabarty, U.S., Mandal, U., Bose, A., Das, A., Ray, K.K., Pal, T.K. Evaluation of the bioequivalence of two faropenem formulations in healthy indian subjects. (2008) Drug Research, 58 (12), pp. 681-685.  
12. Bhaumik, U., Ghosh, A., Mandal, U., Chatterjee, B., Sarkar, A.K., Bose, A., Ray, K.K., Pal, T.K. Determination of drospirenone in human plasma by LC-tandem-MS. (2008) Chromatographia, 68 (9-10), pp. 713-720. 
11. Ghosh, A., Bhaumik, U.K., Bose, A., Mandal, U., Gowda, V., Chatterjee, B., Chakrabarty, U.S., Pal, T.K. Extended release dosage form of glipizide: Development and validation of a level a in vitro-in vivo correlation. (2008) Biological and Pharmaceutical Bulletin, 31 (10), pp. 1946-1951. 
10. Chakrabarty, U.S., Mandal, U., Bhaumik, U., Chatterjee, B., Ghosh, A., Bose, A., Pal, T.K. Bioequivalence study of two capsule formulations containing diacerein 50 mg in healthy human subjects. (2008) Drug Research, 58 (8), pp. 405-409. 
9.  Ghosh, A., Bose, A., Bhaumik, U., Mandal, U., Veeran Gowda, K., Pal, T.K. Application of response surface methodology in the formulation of sustained release matrix tablets of metformin hydrochloride. (2008) Asian Journal of Chemistry, 20 (7), pp. 5541-5556.  
8.  Veeran Gowda, K., Ghosh, A., Bhaumik, U., Agarwal, S., Senthamil Selvan, P., Sahoo, B.K., Nandi, U., Pal, T.K. Single dose bioavailability study of bilayer matrix tablets containing antihypertensive agents. (2008) Asian Journal of Chemistry, 2 (7), pp. 5681-5688. 
7.  Mandal, U., Gowda, V.K., Ghosh, A., Senthamil Selvan, P., Sam Solomon, W.D., Pal, T.K. Development of dissolution medium for glipizide. (2008) Asian Journal of Chemistry, 20 (4), pp. 2651-2656.   
6.  Mandal, U., Ghosh, A., Pal, T.K., Chattaraj, T.K. Bioequivalence study of two formulations containing 30 mg of aripiprazole in healthy human volunteers. (2008) Asian Journal of Chemistry, 20 (2), pp. 1561-1566.  
5.  Mandal, U., Gowda, V., Ghosh, A., Bose, A., Bhaumik, U., Chatterjee, B., Pal, T.K. Optimization of metformin HCl 500 mg sustained release matrix tablets using Artificial Neural Network (ANN) based on Multilayer Perceptrons (MLP) model. (2008) Chemical and Pharmaceutical Bulletin, 56 (2), pp. 150-155. 
 
2007
4. Gowda, K.V., Mandal, U., Senthamil Selvan, P., Sam Solomon, W.D., Ghosh, A., Sarkar, A.K., Agarwal, S., Nageswar Rao, T., Pal, T.K. Liquid chromatography tandem mass spectrometry method for simultaneous determination of metoprolol tartrate and ramipril in human plasma. (2007) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 858 (1-2), pp. 13-21.  
3. Mandal, U., Gowda, V., Ghosh, A., Selvan, S., Solomon, S., Pal, T.K. Formulation and optimization of sustained release matrix tablet of metformin HCl 500 mg using response surface methodology. (2007) Yakugaku Zasshi, 127 (8), pp. 1281-1290. 
2. Mandal, U., Ray, K.K., Gowda, V., Ghosh, A., Pal, T.K. In-vitro and in-vivo correlation for two gliclazide extended-release tablets. (2007) Journal of Pharmacy and Pharmacology, 59 (7), pp. 971-976.  
 
2006
1. Mandal, U., Rajan, D.S., Bose, A., Gowda, K.V., Ghosh, A., Pal, T.K. Development and validation of an HPLC method for analysis of etoricoxib in human plasma. (2006) Indian Journal of Pharmaceutical Sciences, 68 (4), pp. 485-489.  

 

  Member of Professional Bodies
 

Member, Association of Pharmaceutical Teachers of India (APTI)

  Current Sponsored Projects
 
Ongoing:
1. Title: To develop chemically modified non-toxic bio polymers for therapeutically effective controlled drug delivery system.
Total Grant amount: 36.76 L
Period: 2015 - 2018
Sponsored by: EMR, SERB-DST 
Status: Ongoing
Role: Principal Investigator
 
2. Title: Prophylactic Transdermal  Patch against  Neurotoxin Poisoning  in  Biological Warfare  Situations
Total Grant amount: 15 L
Period: 2017-2019
Sponsored by: BIRAC-SRISTI-GYTI 
Status: Ongoing
Role: Supervisor
 
Completed:
1. Title: In-vitro characterization of Microsponge loaded gel for wound healing - evaluation of safety and efficacy.
Total grant amount: 9.27 L
Period: 2011 - 2015
Sponsored by: DRDO
Status: Completed
Role: Principal Investigator
 
2. Title: Improvement of bioavailability of poorly water soluble drugs by micronization and establishment of Lavel A In vitro - In Vivo correlation.
Total Grant amount: 6.42 L
Period: 2012 - 2015
Sponsored by: UGC-MRP
Status: Completed
Role: Principal Investigator
  Text and Reference Books
 
Book Chapter:
1. Ghosh, A., & Wong, T.W. (2014). Graft Copolymers of Guar Gum vs. Alginate: Drug Delivery Applications and Implications. In C.H.Chan, C.H.Chia & S. Thomas (Eds.), Physical Chemistry of Macromolecules Macro to Nanoscales (pp. 423-440). New Jersey Apple Academic Press Inc.
2. Banerjee, S., & Ghosh, A., (2016). Organic - Inorganic Nanocomposites for Biomedical Applications. In S. Maiti and K. K. Sen (Eds.), Bio-Tragets and Drug Delivery Approaches (pp. 375-403). CRC Press, Taylor & Francis Group.
3. Soni, SR., & Ghosh, A. (2017). Grafting Onto Biopolymers: Application in Targeted Drug Delivery. In Vijay Kumar Thakur (Ed). Biopolymer Grafting: Applications (335-389). Elsevier, Amsterdam, Netherlands. 
  Patent
 
 Patent Applied:
1. Pronobesh Chattopadhyay, Subham Banerjee, Animesh Ghosh, Vijay Veer. Matrix Type Transdermal Patch Formulations. (2013). Indian Patent Application No: 3033/DEL/2013.
2. Jinu Isaac, Animesh Ghosh, Swastika Ganguly, Santanu Kaity. Delivery of telmisartan by making formulations containing nanocrystals or disordered crystals of it and a process without use of alkalanizers or solvents for the preparation thereof. (2014). Indian Patent Application No: 830/KOL/2014.
  Fellow
 

 PhD Scholar

(Awarded)

1. Santanu Kaity 

2. Subham Banerjee 

3. Jinu Isaac

Thesis Submitted

1. P. Mahesh Kumar

Ongoing

1. Saundray Raj Soni

2. Nimmy Kumari