Birla Institute of Technology, Mesra
   
DR. MANIK GHOSH
Assistant Professor , Pharmaceutical Sciences and Tech
M. Pharm., Ph.D., R.Ph.
Contact Address
Residence Address RahdeKrishna Mandir, Ashalata Bhawan, Mishra Toli, Khunti - 835210
Permanent Address Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi - 835215
Phone (Office) 00916512276247
Phone Residence 00916512276247
Email Id manik@bitmesra.ac.in
   Joined Institute on : 13-Aug-2006

  Work Experience
 
Teaching : 14.0 Years

Research : 15.0 Years

Individual: 15.0 Years


  Professional Background
 
  • Assistant Professor, Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi (14/08/2006 to Till Date) – Employee Code: 08949
  • Lecturer, Royal College of Pharmacy & Health Sciences, Berhampur (Under Biju Patnaik University of Technology, Rourkela) (20/12/2004 to 12/08/2006) 
  • Lecturer, Maharaja Surajmal College of Pharmacy, Bharatpur, Rajasthan (Under Rajasthan University, Jaipur) (29/05/2004 to 19/12/2004) 

  Research Areas
 
  • Pharmaceutical Chemistry
  • Analytical & Bioanalytical Studies
  • Phytochemistry
  • Computer Aided Drug Design (Molecular Modeling & Docking Studies)
  • Antiviral and Anticancer Research
  • Microwave assisted synthesis of Ionic Liquids

  Award and Honours
 
  • Associate Faculty, FDP101x & FDP201x organized by IIT Bombay, Aug-Nov 2017
  • SAP Award of Excellence - AICTE approved FDP by IIT Bombay on "Use of ICT in Education for Online and Blended Learning" by IIT Bombay (IITBombayX: FDPICT001x): May 02 - Aug 13, 2016
  • USC Programa de Excelencia Investigadora PEIN : INDIA scholarship as Academic Staff in Organic Chemistry, Faculty of Science, Universidad de Santiago de Compostela, Lugo, Spain: Jan-Feb, 2013
  • Special Appreciation Prize in Oral Session of AICTE Sponsored National Seminar on “Emerging Trends in Pharmaceutical Education & Research” Royal College of Pharmacy & Health Sciences, Berhampur, Orissa: July 20 – 22, 2007

   Publications
 
  1. Suddhasattya Dey, Souvik Basak, Anjan De, Shahreja Parvez, Tabassum Hossain, Achintya Saha, Manik Ghosh, Tanushree Karmakar, Simultaneous Pharmacokinetics Estimation of Nateglinide and Pioglitazone by RP-HPLC: Computational Study to Unlock the Synergism, Journal of Chromatographic Science, , bmz116, (https://doi.org/10.1093/chromsci/bmz116)
  2. Suddhasattya Dey, Manik Ghosh*. Bioactivity-guided isolation of Laccaic Acid-A: A potent anti-cancer agent from Laccifer lacca (Kerr).  Indian Journal of Traditional Knowledge 2019; 18(4): 677-685. (http://nopr.niscair.res.in/handle/123456789/50640) ISSN: 0975-1068 (Online); 0972-5938 (Print)
  3. Kamal Kant, Uma Ranjan Lal, Manik Ghosh*. Antibacterial Activity with Bacterial Growth Kinetics and GC-MS Studies on Leaf and Tuber Extracts of Arisaema tortuosum (Wall.) Schott. Indian Journal of Pharmaceutical Education and Research, 53(3[2]), S280-S287, 2019 (https://doi.org/10.5530/ijper.53.3s.98)
  4. Shruti Nayan, Chanchal Kumar Mishra, Divya Priyadarshini, Kishanta Kumar Pradhan, Manik Ghosh, Ashok Pattnaik. Wound Healing Activity of Gel Formulated Leaves Extract of Neolamarckia cadamba (Roxb) Bosser. Indian Journal of Pharmaceutical Education and Research, 53(3[2]), S416-S422, S287, 2019 (https://doi.org/10.5530/ijper.53.3s.114)
  5. Gourav Kumar, Manik Ghosh, Dev Pandey. Method development for optimized green synthesis of gold nanoparticles from Millettia pinnata and their activity in Non-small cell lung cancer cell lines. IET Nanobiotechnology, 13 (6):626-633, 2019 (https://doi.org/10.1049/iet-nbt.2018.5410)
  6. Kamal Kant, Uma Ranjan Lal, Anoop Kumar, Manik Ghosh*. A merged molecular docking, ADME-T and dynamics approaches towards the genus of Arisaema as herpes simplex virus type 1 and type 2 inhibitors.  Computational Biology and Chemistry 78 (2019) 217–226. (https://doi.org/10.1016/j.compbiolchem.2018.12.005)
  7. Suddhasattya Dey, Manik Ghosh*. A LC/MS-MS Guided Isolation of Laccaic Acid-A: A Potent Antimicrobial Agent. Indian J of Pharmaceutical Education and Research. 2018;52(4 Suppl 2):S287-S295. (https://doi.org/10.5530/ijper.52.4s.109)
  8. Padma Charan Behera, Manik Ghosh*. Evaluation of antioxidant, antimicrobial, and antiurolithiatic potential of different solvent extracts of Aerva lanata linn flowers. Pharmacognosy Magazine 2018; 14(53): 53-57. (https://doi.org/10.4103/pm.pm_60_17)
  9. Manuela Donalisio, Valeria Cagno, Andrea Civra, Davide Gibellini, Giuseppina Musumeci, Massimo Rittà, Manik Ghosh, David Lembo. The traditional use of Vachellia nilotica for sexually transmitted diseases is substantiated by the antiviral activity of its bark extract against sexually transmitted viruses. Journal of Ethnopharmacology 2018; 213: 403–408. (https://doi.org/10.1016/j.jep.2017.11.039)
  10. Suddhasattya Dey, Shreya Shah, Manik Ghosh, Neha Karki, Souvik Basak and Nanda Gopal Sahoo. A Novel, Quick Column Switching RP-HPLC Guided Metabolite Profiling of Albendazole-Praziquantel in Rat Plasma: Designing New Combination Dosage Regimen with Higher Therapeutic Window. Current Analytical Chemistry, 2018 (http://dx.doi.org/10.2174/1573411014666171206152945)
  11. Kamal Kant, Uma Ranjan Lal, Manik Ghosh*. In silico prediction and wet lab validation of Arisaema tortuosum (Wall.) schott extracts as antioxidant and anti-breast cancer source: A comparative study. Pharmacognosy Magazine 2017; 13(52): 786-790. (https://doi.org/10.4103/pm.pm_69_17)
  12. Kamal Kant, Uma Ranjan Lal, Manik Ghosh*. Computational breakthrough of natural lead hits from the genus of Arisaema against human respiratory syncytial virus. Pharmacognosy Magazine 2017; 13(52): 780-785. (https://doi.org/10.4103/pm.pm_459_16)
  13. Manik Ghosh*, Andrea Civra, Massimo Rittà, Valeria Cagno, Siva Ganesh Mavuduru, Preeti Awasthi, David Lembo, Manuela Donalisio. Ficus religiosa L. bark extracts inhibit infection by herpes simplex virus type 2 in vitro. Archives of Virology 2016; (http://dx.doi.org/10.1007/s00705-016-3032-3) ISSN: 0304-8608 (Print); 1432-8798 (Online)
  14. Padma Charan Behera, Bama Prasad Bag & Manik Ghosh*. Anti-urolithiatic activity of hydrogenated naphthol isolated from Aerva lanata (L.) Juss. flower extract. Indian Journal of Traditional Knowledge 2016; 15(3): 453-459.
  15. Valeria Cagno, Andrea Civra, Ravi Kumar, Subhankar Pradhan, Manuela Donalisio, Barij Nayan Sinha, Manik Ghosh*, David Lembo*. Ficus religiosa L. bark extracts inhibit Human Rhinovirus and Respiratory Syncytial Virus infection in vitro. Journal of Ethnopharmacology 2015, 176:252-257. (http://dx.doi.org/10.1016/j.jep.2015.10.042) ISSN: 0378-8741 (Print)
  16. Chandradeep Singh, Pushpani Sharma, Trishna Bal, Manik Ghosh, Ram Dubey and Soumyajit Das. Preparation and evaluation of Radiosensitizing agent Nimorazole in topical emulgel. Der Pharmacia Lettre 2015, 7(9):132-142. (http://scholarsresearchlibrary.com/dpl-vol7-iss9/DPL-2015-7-9-132-142.pdf) ISSN: 0975-5071
  17. A. Kumar, R.K. Dubey, K. Kant, D. Sasmal, M. Ghosh, and N. Sharma. Determination of Deltamethrin in Mice Plasma and Immune Organs by Simple Reversed-Phase HPLC. Acta Chromatographica (http://dx.doi.org/10.1556/1326.2016.28.2.4) ISSN: 1233-2356 (Print) ISSN: 2083-5736 (Online)
  18. Ramkumar Dubey; Manik Ghosh*; Barij Nayan Sinha; Venkateswari Muthukrishnan. Simultaneous Determination and Pharmacokinetics of Metolazone, Losartan and Losartan Carboxylic Acid in Rat Plasma by HPLC–ESI–MS-MS. Journal of Chromatographic Science 2015; (http://dx.doi.org/10.1093/chromsci/bmv047) ISSN 0021-9665 (Print) ISSN 1945-239X (Online) 
  19. Soumyajit Das, Ramkumar Dubey, Subhradip Roychowdhury, Manik Ghosh*, Barij Nayan Sinha, Kishanta Kumar Pradhan, Trishna Bal, Venkateswari Muthukrishnan, Julio A. Seijas, Abhijit Pujari. A rapid and sensitive determination of hypoxic radiosensitizer agent nimorazole in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. Biomedical Chromatography, 2015; (http://dx.doi.org/10.1002/bmc.3461) ISSN 0269-3879 (Print) ISSN 1099-0801 (Online)
  20. Ramkumar Dubey, Manik Ghosh*. Simultaneous Determination and Pharmacokinetic Study of Losartan, Losartan Carboxylic Acid, Ramipril, Ramiprilat, and Hydrochlorothiazide in Rat Plasma by a Liquid Chromatography/Tandem Mass Spectrometry Method. Sci. Pharm. 2015; 83(1): 107–124. (http://dx.doi.org/10.3797/scipharm.1410-15) ISSN 0036-8709 (Print) ISSN 2218-0532 (Online)
  21. Siva Ganesh M, Preeti Awasthi, Ajay Kumar Timiri and Manik Ghosh*. A novel approach for rationale selection of medicinal plants against viruses via molecular docking studies. The Pharmstudent 2015: 18-30. ISSN 0379-556X (Print)/ ISSN 2347-6001 (Online)
  22. Ladli Kumari, Papiya Mitra Mazumder, Manik, UR Lal and R Dubey. High performance thin layer chromatography fingerprint profile, isolation, its antioxidant activity and spectroscopic characterization of marker compound of Murraya koenigii. Journal of Pharmacognosy and Phytochemistry 2014; 3(4): 86-92. (http://www.phytojournal.com/vol3Issue4/19.1.html) E-ISSN: 2278-4136; P-ISSN: 2349-8196
  23. Aditi Paul; Trishna Bal; Ram Dubey; Manik Ghosh. A Statistical Approach Towards Development and Optimization of Conventional Immediate Release Tablet of Nimorazole by Wet Granulation Technique. Iranian Journal of Pharmaceutical Sciences 2013; 9(4): 23-38. (http://www.ijps.ir/pdf_10244_dc013890be33e6456e30a2cbd206c798.html) ISSN: 1735-2444
  24. Preeti Awasthi, Siva G Mavuduru, Manik Ghosh*. Ayurveda: Combating Viral Diseases since Ages. PHARMBIT, Jul – Dec 2013; XXVIII (2): 25-30.  (http://www.bitmesra.ac.in/cms.aspx?this=1&mid=672&cid=480) ISSN: 0973-6204
  25. Ratna Ghosh, Reshma Xalxo and Manik Ghosh. Estimation of Heavy Metal in Vegetables From Different Market Sites of Tribal Based Ranchi City Through ICP-OES and to Assess Health Risk. Current World Environment 2013, 8(3): 435-444. (http://dx.doi.org/10.12944/CWE.8.3.13) ISSN: 0973-4929, Online ISSN: 2320-8031
  26. Manoj Goyal, Manik Ghosh, B.P. Nagori, D. Sasmal. Analgesic and anti-inflammatory studies of cyclopeptide alkaloid fraction of leaves of Ziziyphus nummularia. Saudi Journal of Biological Sciences 2013, 20(4): 365-371. (http://dx.doi.org/10.1016/j.sjbs.2013.04.003) ISSN: 1319-562X
  27. Mukul Chandra Gope, Ratna Ghosh, Manik Ghosh, Rupali Patra. Relative Efficiencies of the Dietary Proteins of Plant and Animal Origin : A Comparative Study. PHARMBIT, Jan – Dec 2011; XXIII & XXIV (1& 2): 53-56. (http://www.bitmesra.ac.in/cms.aspx?this=1&mid=672&cid=480) ISSN: 0973-6204
  28. Ratna Ghosh, Reshma Xalxo, Mukul Chandra Gope, Sougata Mishra,  Bindu Kumari, Manik Ghosh. Estimation of Heavy Metals in locally available Vegetables collected from Road Side Market Sites (1-4) of different areas of Ranchi City. PHARMBIT, Jan – Dec 2011; XXIII & XXIV (1& 2): 68-73. http://www.bitmesra.ac.in/cms.aspx?this=1&mid=672&cid=480) ISSN: 0973-6204
  29. Manik*, B.N. Sinha and D. Sasmal. Psychopharmacological and Anticonvulsant effects of Litsea polyantha Juss. bark extract in mice: Role of serotonergic pathways. Asian Journal of Chemistry 2011, 23(1): 315-318. ISSN: 0970-7077
  30. Manik Ghosh* and B.N. Sinha. GC-MS Studies on the Bark Extracts of Litsea polyantha Juss. Middle East Journal of Scientific Research 2010, 5 (6): 441-444. (http://www.idosi.org/mejsr/mejsr5(6).htm) ISSN: 1990-9233 EISSN : 1999-8147
  31. Suddhasattya Dey, Y.Vikram Reddy, Bala Krishna, Sudhhir Kumar Sahoo, P.N. Murthy, Dhiraj Kumar, Juneid Alam and Manik Ghosh. Spectrophotometric Estimation of Gemifloxacin in bulk and Pharmaceutical dosage form by UV Spectrophotometry. International Journal of Chemical and Analytical Science 2010, 1(6), 130-133. (http://ijcas.info/article/download/2772/1458) ISSN: 0976-1209
  32. Arjun Patra, S. Jha, P.N. Murthy, Manik, A. Sharone. Isolation and characterization of stigmast-5-en-3ß-ol (ß-sitosterol) from the leaves of Hygrophila spinosa T. Anders. International Journal of Pharma Sciences and Research, 2010, 1(2), 95-100. (http://www.ijpsr.info/docs/IJPSR-10-01-02-03.pdf) ISSN: 0975-9492
  33. Trishna Bal, Ramadevi Pulella, Shikha Prasad, Rajni Gupta, P. N. Murthy, Manik Ghosh. Preparation and In-vitro Evaluation of Varapamil hydrochloride Microcapsules. PHARMBIT, Jul – Dec 2009; XX (2): 119-125. ISSN: 0973-6204
  34. Ayushman Tiwari, Manik Ghosh, Sridhar Narayan, Pradeep Kumar and Rakesh K Sindhu. Simultaneous analysis of Paracetamol and Tramadol – Analytical method development & validation. Der Pharma Chemica, 2009, 1(2): 72-78. (http://derpharmachemica.com/second-issue/9.DPC-1_2_72-78.html) ISSN: 0975-413X
  35. Manik*, B. N. Sinha and S. R. Swain. Sub-chronic Toxicity Studies of the Alcoholic Extract of Litsea polyantha Juss. Bark. Pharmacologyonline, May-August 2009; 2: 1106-1110. (http://pharmacologyonline.silae.it/files/archives/2009/vol2/109_exN35_Manik.pdf) ISSN: 1827-8620
  36. J. Sahoo, P. N. Murthy, S. Biswal and Manik*. Formulation of Sustained-Release Dosage Form of Verapamil Hydrochloride by Solid Dispersion Technique Using Eudragit RLPO or Kollidon®SR. AAPS PharmSciTech, March 2009;10(1): 27-33. (http://dx.doi.org/10.1208/s12249-008-9175-0) ISSN: 1530-9932
  37. Ratna Gope and Manik “Assessment of Dietary Micronutrients in Institutionalized Geriatric” PHARMBIT, Jan-Jun 2008; XVII (1): 69-73. ISSN: 0973-6204
  38. Abhimanyu Dev & Manik. “Gene Knockout” PHARMBIT, Jul – Dec 2007; XVI (2): 105-109. ISSN: 0973-6204
  39. Manik. “Biostatistics Analysis Tools from Microsoft Excel” Pharmawave: The Technical Journal of Pharmacy & Health, 2007; 2/07: 71-81.
  40. Manik & B N Sinha. “Software on Inflammatory Diseases” PHARMBIT Jan – Jun 2007; XV (1); 30-38. ISSN: 0973-6204

  Member of Professional Bodies
 
  • Registered Pharmacist (Jharkhand State) – JH-10
  • Life Member, The Association of Pharmaceutical Teachers of India (APTI) - JKD/LM-16 (Secretary, APTI, Jharkhand State Branch)
  • Life Member, Indian Pharmaceutical Association (IPA) – JHA/LM/0028
  • Life Member, Indian Pharmacy Graduates’ Association (IPGA) - LM-1743 
  • LIfe Member, Pharmaceutical Society, Birla Institute of Technology

  Current Sponsored Projects
 
  • Principal Investigator, ICAR Extramural Research Projects (Agricultural Engineering Division) on "Evaluation of Antiviral and Anticancer potentials of Lac exudate / dye" (22.43 Lakhs)
  • Principal Investigator, Seed Money Scheme, Birla Institute of Technology, Mesra on "Development of Anticancer Formulations from lac based on in-vitro studies on selected Cancer cell lines" (0.80 Lakh)
  • Principal Investigator, UGC Sponsored Research Project on “Estimation of Heavy Metals Toxicity in Vegetables & Medicinal Plants collected from Road Side Market and Organized Market Sites of different areas of Ranchi City” (0.80 Lakh)
  • Co-Investigator, UGC Sponsored Research Project on "Formulation Development and Evaluation of Antiviral Drugs” (0.80 Lakh)

  Text and Refrence Books
 

Book: Studies on Anticancer Agents from Natural Sources. The Tabernaemontana Divaricata (L.) R. Br. ex Roem. & Schult.
by Manik Ghosh and Mavuduru Siva Ganesh
Publisher: GRIN Verlag GmbH
ISBN-10: 3668047588
ISBN-13: 978-3668047587
 
Book: Studies on some semi-synthetic piperine analogous as Central Nervous System Depressants
by Manik Ghosh, Barij Nayan Sinha and Mushtari Akhter
Publisher: GRIN Verlag GmbH
ISBN-10: 3656923892
ISBN-13: 978-3656923893
 
Book: Pharmaceutical Regulatory Affairs (PRA): INTRODUCTION TO REGULATORY AFFAIRS (Module Book 1)
by Manik Ghosh
Kindle Edition
Publisher: PRANATI (Amazon Digital Services, Inc.)
Language: English
ASIN: B014DNO6OA
 
Book: Pharmaceutical Regulatory Affairs (PRA): REGULATORY ACTS AND LAWS (Module Book 2)
by Manik Ghosh
Kindle Edition
Publisher: PRANATI (Amazon Digital Services, Inc.)
Language: English
ASIN: B014DMB60I

Book: Antioxidant Guided Chemical Investigations of Picrorhiza Kurroa
by Kamal Kant, Vijai Kant Agnihotri and Manik Ghosh
Publisher: LAP LAMBERT Academic Publishing
ISBN-10: 3659706256
ISBN-13: 978-3659706257

Chapter: Plant Based Natural Products and Drug Discovery
by Alakh N Sahu, Arjun Patra, Manik Ghosh and Jitendra Kumar
Book: Environmental & Health Research
Publisher: SEDER, Varanasi
ISBN-13:978-81-909022-8-1

Chapter: Litsea polyantha JUSS. – Folklore of Jharkhand
by Manik Ghosh, Barij Nayan Sinha and Julio A. Seijas
Book: Ethnomedicinal Plants; Phytochemistry & Pharmacological Profiles
Publisher; AGROBIOS (India), Jodhpur
ISBN-978-81-7754-662-0


Visit:
http://www.amazon.in/Manik-Ghosh/e/B014G6I37U
http://www.amazon.com/Manik-Ghosh/e/B014G6I37U



  Fellow
 

Mrs. Rojalini Samanta: PHD/PH/10051/2017 - ongoing

Mr. Suddhayasattya Dey: PHD/PH/10003/2016 - ICAR - Senior Research Fellow: 2016 - 2019 (Submitted)

Mr. Kamal Kant: PHD/PH/10051/2012 - UGC - Basic Science Research Senior Research Fellow: 2013 – 2019 (Ph.D. Awarded)

Mr. Padma Charan Behera; PHD/PH/1053/2011 - UGC - Rajiv Gandhi National Fellow: 2012 – 2019 (Ph.D. Awarded) 

Mr. Ram Kumar Dubey: PHD/PH/1051/2011 BIT Mesra - Institute Fellow: 2012 – 2016 (Ph.D. Awarded)


  Member, Editorial Board
 

Chief Editor, PHARMBIT (ISSN: 0973-6204) - Scientific Journal of Pharmaceutical Society, BIT Mesra

Member, Editorial Board, Journal of Natural Remedies (Print ISSN: 0972-5547; Online: 2320-3358)

Reviewing Editor, World Research Journal of Pharma Technology (ISSN: 2454-5546)

Editor, Pharmaceutical Drug Regulatory Affairs Journal (PDRAJ)